Tag:

Alzheimer’s disease

Functional neurological disorders
Apolipoprotein E (APOE) and Alzheimer’s disease risk in a Ugandan population: A pilot case-control study

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Apolipoprotein E Genotypes and Alzheimer’s Disease The study investigated the relationship between different genotypes of …

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Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological Tau Phosphorylation Mechanisms Tau protein is a key player in maintaining the structural integrity …

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Dementia
Unraveling sex differences in Alzheimer’s disease and related endophenotypes with brain proteomes

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Research Context The study of Alzheimer’s disease (AD) has gained considerable momentum as researchers explore …

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Traumatic brain injury
Using baseline MRI radiomic features to predict the efficacy of repetitive transcranial magnetic stimulation in Alzheimer’s patients

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview This study investigates the potential of baseline MRI radiomic features to forecast the …

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Traumatic brain injury
Using baseline MRI radiomic features to predict the efficacy of repetitive transcranial magnetic stimulation in Alzheimer’s patients

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview This study investigates the potential of baseline MRI radiomic features to predict the …

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Functional neurological disorders
Cholinergic degeneration in prodromal and early Parkinson’s: a link to present and future disease states

by myneuronews May 6, 2025

by myneuronews May 6, 2025

Cholinergic Pathways in Parkinson’s Disease In the context of Parkinson’s disease, understanding the role of …

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Traumatic brain injury
Collision Sports and Neurodegenerative Disease: Inclusion of Moderating Risk Factors

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Impact of Collision Sports on Neurodegenerative Risk Participation in collision sports can have significant implications …

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Dementia
Association of Alzheimer’s Disease and Related Dementias (ADRD) With Days at Home Among Medicare Beneficiaries After a Heart Failure Hospitalization

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Association With Days at Home The amount of time spent at home after a hospitalization …

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Functional neurological disorders
Brain-wide microglia replacement using a nonconditioning strategy ameliorates pathology in mouse models of neurological disorders

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Microglia Replacement Strategy The study introduces an innovative approach to addressing neurological disorders through the …

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Functional neurological disorders
Silencer variants are key drivers of gene upregulation in Alzheimer’s disease

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Silencer Variants and Gene Regulation Recent advancements in genetic research have shed light on the …

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An update on hypophysitis
Study Overview Recent research has focused on the complexities of hypophysitis, an inflammation of the…
Identification of expanded and interrupted ATXN2 repeat expansions in Parkinson’s disease and Lewy Body Dementia cohorts
Study Overview This research investigates the presence and significance of expanded and interrupted repeat expansions…
Intracranial Injury Caused by Transorbital Penetrating Trauma: An E-Scooter Brake Handle as an Unusual Culprit
Study Overview In recent years, the popularity of e-scooters has surged, bringing with it a…
The Influence of Aerobic Exercise Therapy on Patient-Reported Outcome Measures Following Concussion: A Scoping Review
Study Overview The rising recognition of concussion as a significant public health concern has sparked…
A Bioinformatic Study of Genetics Involved in Determining Mild Traumatic Brain Injury Severity and Recovery
Genetic Factors in Traumatic Brain Injury Traumatic brain injury (TBI) represents a significant public health…

Smart technologies and the future of concussion prevention in ice hockey
BACKGROUND: Concussions in ice hockey remain a major concern, especially among young players. Current helmets mainly protect against skull fractures but offer limited shielding from brain acceleration forces.
Intracranial Injury Caused by Transorbital Penetrating Trauma: An E-Scooter Brake Handle as an Unusual Culprit
Transorbital penetrating intracranial injuries are a rare but life-threatening subset of penetrating head traumas. While isolated cases caused by bicycle brake handles have been reported, often with fatal outcomes, this is the first documented case of such an injury caused by an electric scooter (e-scooter) brake handle. The objective is to present the unique management […]
The Influence of Aerobic Exercise Therapy on Patient-Reported Outcome Measures Following Concussion: A Scoping Review
Background/Objectives: The purpose of this scoping review was to identify the effects of exercise therapy on patient-reported outcome measure(s) (PROM(s)) after concussion, and to highlight the current knowledge gaps in the literature. Methods: A search of EMBASE, MEDLINE, SCOPUS, BIOSIS, and Cochrane Libraries was performed on 1 December 2023 (from database inception) and updated on […]
A Bioinformatic Study of Genetics Involved in Determining Mild Traumatic Brain Injury Severity and Recovery
Objectives: This in silico study sought to identify specific biomarkers for mild traumatic brain injury (mTBI) through the analysis of publicly available gene and miRNA databases, hypothesizing their influence on neuronal structure, axonal integrity, and regeneration. Methods: This study implemented a three-step process: (1) data searching for mTBI-related genes in Gene and MalaCard databases and […]
Concussion-Related Cognitive and Lipid Changes in Retired UK Rugby Players Study
Long-term effects of concussions, particularly in contact sport athletes, have been linked to changes in neuronal health. Lipid dysregulation has emerged as a potential contributor to neuronal injury and may serve as a measurable biomarker of brain pathology. This study investigated cognitive scores and serum lipid biomarkers in retired rugby players with a history of […]