Study Overview This study centers on the intricate relationships between cellular profiles in the human …
astrocytes
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Traumatic brain injury
The kynurenine pathway in pediatric “mild-to-moderate” traumatic brain injury: translational insights from a prospective human study and a large-animal model
by myneuronewsby myneuronewsKynurenine Pathway Mechanisms The kynurenine pathway is a critical metabolic route for the amino acid …
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Traumatic brain injury
Targeted complement inhibition ameliorates the pathological and cognitive outcomes in repetitive mild closed head injury
by myneuronewsby myneuronewsStudy Overview The investigation into the effects of targeted complement inhibition on outcomes following repetitive …
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Dementia
Loss of C9orf72 impacts the peripheral neuromuscular system via immune dysregulation and accelerates the progression of amyotrophic lateral sclerosis in SOD-1 mutant mice
by myneuronewsby myneuronewsImpact of C9orf72 Loss on Neuromuscular Systems The loss of the C9orf72 gene has been …
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Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity
by myneuronewsby myneuronewsBiomarkers in cerebrospinal fluid analysis Cerebrospinal fluid (CSF) serves as a crucial medium for assessing …
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Traumatic brain injury
Therapeutic VEGFC treatment provides protection against traumatic-brain-injury-driven tauopathy pathogenesis
by myneuronewsby myneuronewsTherapeutic Efficacy of VEGFC The treatment of traumatic brain injury (TBI) has been a significant …
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Traumatic brain injury
Evolution of Axonal Injury in the Closed Head Impact Model of Engineered Rotational Acceleration in Adult Ferrets
by myneuronewsby myneuronewsStudy Overview This research investigates the progression of axonal injury resulting from a model of …
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Traumatic brain injury
AQP4 in cerebrospinal fluid correlates with severity and prognosis in moderate to severe traumatic brain injury
by myneuronewsby myneuronewsBackground and Rationale Traumatic brain injury (TBI) is a significant public health concern, often resulting …
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Traumatic brain injury
Association of Preinjury Beta-Blocker Exposure With Brain Injury Biomarkers Following Traumatic Brain Injury
by myneuronewsby myneuronewsStudy Overview This study investigates the connection between preinjury exposure to beta-blockers and the levels …
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Traumatic brain injury
CD300f enables microglial damage sensing, efferocytosis, and apoptotic cell metabolization after brain injury
by myneuronewsby myneuronewsMicroglial Function in Brain Injury Microglia, the primary immune cells of the central nervous system, …
