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axonal degeneration

  • Traumatic brain injury

    Evolution of Axonal Injury in the Closed Head Impact Model of Engineered Rotational Acceleration in Adult Ferrets

    by myneuronews October 30, 2025
    by myneuronews October 30, 2025

    Study Overview This research examines the impact of engineered rotational acceleration on axonal injury in …

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  • Traumatic brain injury

    Blocking axon-glial mechanotransduction to prevent concussive brain injury

    by myneuronews September 30, 2025
    by myneuronews September 30, 2025

    Study Overview The research focuses on preventing concussive brain injuries through the inhibition of mechanotransduction …

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  • Traumatic brain injury

    Sensitivity of Diffusion Tensor Imaging for Assessing Injury Severity in a Rat Model of Isolated Diffuse Axonal Injury: Comparison with Histology and Neurological Assessment

    by myneuronews August 14, 2025
    by myneuronews August 14, 2025

    Study Overview This investigation centers on the evaluation of diffusion tensor imaging (DTI) as a …

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  • Traumatic brain injury

    Multimodal Magnetic Resonance Imaging with Mild Repetitive Head Injury in Awake Rats: Modeling the Human Experience and Clinical Condition

    by myneuronews June 29, 2025
    by myneuronews June 29, 2025

    Study Overview This study investigates the effects of mild repetitive head injuries on brain function …

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  • Functional neurological disorders

    Fluid Biomarkers in Demyelinating Spectrum Disorders: Past, Present, and Prospects

    by myneuronews May 14, 2025
    by myneuronews May 14, 2025

    Fluid Biomarker Applications in Demyelinating Disorders Fluid biomarkers play a crucial role in the diagnosis …

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  • Medical professionalsPost traumatic epilepsyTraumatic brain injury

    Understanding the Pathophysiology of Post-Traumatic Epilepsy

    by Ioannis Mavroudis February 14, 2024
    by Ioannis Mavroudis February 14, 2024

    Astrocytes, traditionally viewed as mere support cells, play a pivotal role in the development of …

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  • Current trends and projections for potential acupuncture needs globally and in China: evidence from the Global Burden of Disease Study 2021
    Global Acupuncture Needs Assessment The assessment of global acupuncture needs involves a multi-faceted approach that…
  • Plasma extracellular vesicles and phosphorylated tau 181 as early biomarkers of cognitive impairment in Alzheimer’s dementia
    Study Overview The focus of this research is on exploring the potential of plasma extracellular…
  • Development and Evaluation of Upper Extremity Movement Quality Outcome Measures for Individuals with Functional Movement Disorder
    Methodology for Movement Quality Assessment The study employed a comprehensive methodology for assessing upper extremity…
  • The Clinical Utility of a Novel Multimodal Assessment Battery for Acute Sport-Related Concussion
    Assessment Framework The evaluation of acute sport-related concussions necessitates a multidimensional approach that integrates various…
  • Associations of Symptomatic Head Trauma/Concussion Diagnosis with Sleep-Related Outcomes in Children
    Study Background The relationship between head trauma and its subsequent effects on children’s sleep patterns…

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Research

  • Management of the paediatric patient with acute head trauma
    Acute head trauma (AHT) leading to traumatic brain injury is an important cause of paediatric morbidity and mortality. Injury severity depends on the mechanism of trauma and age of the child. The vast majority of childhood AHT cases are mild, require no therapy, and leave no long-term sequelae. However, it is important to identify individuals […]
  • Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
    CONCLUSION: Post-concussion sex differences in creatine concentrations were detected, as higher creatine levels moderately correlated with patient-reported outcomes. Creatine may reflect altered energy dynamics in the brain. The absence of a non-injured control group limits determination of whether these differences are concussion-specific or reflective of baseline physiology.
  • Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
    Chronic neuroinflammation is recognized as a pivotal mechanism responsible for secondary damage following mild traumatic brain injury (mTBI), underscoring the critical need for therapeutic strategies capable of mitigating this pathological process. This study evaluated the anti-inflammatory properties of stearidonic acid ethanolamide (SDEA, C20H33NO2). The findings indicate that mTBI triggers persistent neuroinflammation, which is correlated with […]
  • Appropriateness of imaging requests for pediatric traumatic brain injury in the emergency department: a retrospective cross-sectional study
    CONCLUSION: A significant gap exists between clinical practice and guideline-based imaging for pediatric TBI in Chile. Reinforcing validated decision tools may help optimize imaging use and minimize unnecessary radiation exposure.
  • Preexisting Mental Health Disorders Are Associated With Acute Clinical Presentation and Longitudinal Recovery Trajectories in Adolescents With Concussion
    This secondary analysis examined the association between preexisting mental health conditions and clinical recovery trajectories in adolescents with concussion. Adolescents (13-17; n = 1238) completed clinical assessments (Post-Concussion Symptom Inventory [PCSI] ≤48 hours postinjury; PCSI/ Pediatric Quality of Life [PedsQL] for 3 months) and were categorized into control, anxiety, depression, or combined anxiety/depression groups. Acute […]

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