Tag:

biomarkers

Dementia
In an older-age vascular cohort, carotid stenosis is associated with processing speed and executive function cognitive deficits, which correlate with p-tau217

by myneuronews November 17, 2025

by myneuronews November 17, 2025

Study Overview The research focused on understanding the relationship between carotid stenosis and cognitive deficits …

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Traumatic brain injury
Biomarkers for prediction of chronic traumatic encephalopathy-like pathology following repeated mild traumatic brain injury in rats are partially sex- and age-dependent

by myneuronews November 16, 2025

by myneuronews November 16, 2025

Study Overview The research embarked on an investigation into the long-term effects of repeated mild …

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Dementia
Loss of C9orf72 impacts the peripheral neuromuscular system via immune dysregulation and accelerates the progression of amyotrophic lateral sclerosis in SOD-1 mutant mice

by myneuronews November 15, 2025

by myneuronews November 15, 2025

Impact of C9orf72 Loss on Neuromuscular Systems The loss of the C9orf72 gene has been …

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Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Metabolomic Profiling Metabolomic profiling involves the comprehensive analysis of metabolites—small molecules that are the end …

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Functional neurological disorders
Multisite, Multiancestry Genome-Wide Association Study Meta-Analysis of Functional Seizure Disorder in a Hospital Sample of 675,680 Patients

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Study Summary The recent study presents an extensive analysis of functional seizure disorder, conducted through …

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Dementia
Dynamic functional connectivity and transcriptomic signatures reveal stage-dependent brain network dysfunction in Alzheimer’s disease spectrum

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Study Overview The research focused on understanding the intricate relationship between brain network connectivity and …

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Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Biomarkers in cerebrospinal fluid analysis Cerebrospinal fluid (CSF) serves as a crucial medium for assessing …

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Traumatic brain injury
Objective Markers for Diagnosing Concussions: Beyond Blood Biomarkers and the Role of Real-Time Diagnostic Tools

by myneuronews November 13, 2025

by myneuronews November 13, 2025

Diagnostic Innovations Recent advancements in concussion diagnostics have shown promise in enhancing the speed and …

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Functional neurological disorders
Diagnosis and treatment of functional visual disorder

by myneuronews November 11, 2025

by myneuronews November 11, 2025

Understanding Functional Visual Disorder Functional Visual Disorder (FVD) is a complex condition where individuals experience …

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Functional neurological disorders
Phenotyping Functional Gait Disorder: An Exploratory Analysis of Existing Frameworks

by myneuronews November 11, 2025

by myneuronews November 11, 2025

Phenotyping Functional Gait Disorder Functional Gait Disorder (FGD) represents a unique challenge in the field …

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Bioequivalence of Two Perampanel Oral Suspension Formulations in Healthy Subjects: A Randomized Crossover Study
Study Overview The investigation focused on comparing the bioequivalence of two formulations of perampanel oral…
In an older-age vascular cohort, carotid stenosis is associated with processing speed and executive function cognitive deficits, which correlate with p-tau217
Study Overview The research focused on understanding the relationship between carotid stenosis and cognitive deficits…
Functional Neurological Disorder, Sleep, and Dreaming: A Large Online Questionnaire-Based Study
Background on Functional Neurological Disorder Functional Neurological Disorder (FND) encompasses a range of neurological symptoms…
Treatments for Functional Neurological Disorder: A Practical Guide for Program Development
Overview of Functional Neurological Disorder Functional Neurological Disorder (FND) presents a unique challenge in both…
On-tools for rehabilitation and cognitive care: Development of a brief intervention for chronic cognitive difficulties after mild traumatic brain injury
Study Overview The investigation focused on addressing the often-overlooked cognitive challenges faced by individuals who…

Clinical Outcomes in the Patient With Traumatic Brain Injury and Comorbid Obesity: A Scoping Review
Very few studies exist examining the effects of mild traumatic brain injury (mTBI) in patients with obesity, which is notable given that mTBI represents ~80% of all recorded TBIs. Given that approximately 40% of US adults have an obese body mass index (with predictions that this proportion will continue to increase), it would be prudent […]
2Innate immune signaling mediates differential acute and long-term outcomes of repeated vs. single TBI in Drosophila
Traumatic brain injuries (TBIs) are a global source of hospitalization, long-term disability, and death. However, age, sex, and other demographics differ widely among patients and the variable characteristics of TBIs further obscure injury outcomes. Here, we used Drosophila melanogaster to assess the effects of mild, repeated TBI (multi-day, MD) compared to single, severe TBI (single-day, […]
C-FLAIR: Fluid-attenuated Inversion Recovery with Controlled Artifact Suppression in Brain MRI
Background The T2-weighted fluid-attenuated inversion recovery (FLAIR) sequence is part of the routine brain MRI protocol. In regions with strong inhomogeneities in the static magnetic (B(0)) field and/or the radiofrequency (RF) field, inadequate magnetization inversion results in artifacts that may mimic or obscure pathologic features. Purpose To reduce artifacts on FLAIR images by using an […]
Long intervals between repetitive concussions reduce risk of cognitive impairment and limit microglial activation, astrogliosis, and tauopathy in adolescent rats
Although previous studies have demonstrated the effects of concussions do not accumulate as the time interval between injuries increases, little is known about the relationship between this interval and the effects of repetitive concussions. The objective of this study is to explore the relationship between the time interval and changes in behavior and histology following […]
On-tools for rehabilitation and cognitive care: Development of a brief intervention for chronic cognitive difficulties after mild traumatic brain injury
CONCLUSION/IMPLICATIONS: Through a multistep process that incorporated stakeholder input and a review of the empirical literature, we developed an evidence-informed intervention that fills a gap in current care for cognitive PPCSs. Future studies are needed to evaluate the efficacy of this intervention for individuals with chronic cognitive difficulties after mTBI. (PsycInfo Database Record (c) 2025 […]