Tag:

biomarkers

Traumatic brain injury
CCL5/RANTES signaling in inflammation dysregulation after mild traumatic brain injury

by myneuronews January 8, 2026

by myneuronews January 8, 2026

CCL5/RANTES Role in Brain Injury CCL5, also known as RANTES (Regulated upon Activation, Normal T …

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Traumatic brain injury
A Longitudinal Study of Error-Related Neural Responses in Adolescents Following Mild Traumatic Brain Injury (mTBI)

by myneuronews January 8, 2026

by myneuronews January 8, 2026

Study Overview The study investigates the neural responses associated with error monitoring in adolescents who …

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Traumatic brain injury
Stability of salivary microRNA measures across an NCAA Division I football season: Implications for microRNA as a biomarker of concussion

by myneuronews January 8, 2026

by myneuronews January 8, 2026

Study Overview The focus of this research is on salivary microRNAs and their stability throughout …

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Traumatic brain injury
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion

by myneuronews January 8, 2026

by myneuronews January 8, 2026

Study Overview The investigation focused on the relationship between brain creatine concentrations and both sex …

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Functional neurological disorders
Update on functional vestibular and gait disorders

by myneuronews January 8, 2026

by myneuronews January 8, 2026

Current Understanding of Vestibular and Gait Disorders Vestibular and gait disorders have increasingly garnered attention …

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Functional neurological disorders
Structural brain alterations and predictors of clinical improvement in functional cognitive disorder after concussion

by myneuronews January 7, 2026

by myneuronews January 7, 2026

Structural Brain Alterations Recent research has illuminated the intricate relationship between structural brain alterations and …

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Dementia
Plasma extracellular vesicles and phosphorylated tau 181 as early biomarkers of cognitive impairment in Alzheimer’s dementia

by myneuronews January 6, 2026

by myneuronews January 6, 2026

Study Overview The focus of this research is on exploring the potential of plasma extracellular …

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Functional neurological disorders
Functional neurological disorder: an evolutionary perspective

by myneuronews January 5, 2026

by myneuronews January 5, 2026

Evolutionary Perspectives on FND The concept of Functional Neurological Disorder (FND) can be significantly enriched …

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Dementia
GASDERMIN D-mediated pyroptosis as a therapeutic target in TAU-dependent frontotemporal dementia mouse model

by myneuronews January 4, 2026

by myneuronews January 4, 2026

Study Overview The research focuses on the role of GASDERMIN D in the context of …

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Functional neurological disorders
Patient-reported outcomes and acceptability of suggestion and hypnosis-based therapy for functional neurological disorder within an NHS service

by myneuronews January 4, 2026

by myneuronews January 4, 2026

Patient Experiences and Feedback In examining the experiences and feedback provided by patients undergoing suggestion …

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Real-world assessment of current migraine prophylaxis in Egypt: a multicenter national study
Study Overview The research conducted aimed to evaluate the existing practices regarding migraine prophylaxis across…
Treatment of Alzheimer’s disease from gut-brain interactions based on theory of “spleen deficiency leading to obstruction of nine orifices”
Understanding Gut-Brain Interactions The relationship between the gut and the brain is increasingly recognized as…
Update on functional vestibular and gait disorders
Current Understanding of Vestibular and Gait Disorders Vestibular and gait disorders have increasingly garnered attention…
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
Study Overview The investigation focused on the relationship between brain creatine concentrations and both sex…
Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
Study Overview This study investigates the effects of stearidonic acid ethanolamide (SDA-EA) on inflammation following…

Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]
Explosive shock wave exposure leads to age-accelerated motor and sensory decline in C. elegans
CONCLUSIONS: Defined shock wave exposure is sufficient to provoke long-term neuronal functional decline in C. elegans , accompanied by structural deterioration and premature neurodegeneration. This tractable model enables lifelong phenotyping and mechanistic dissection of how an acute shock wave insult progresses to chronic neuronal dysfunction, and provides a scalable platform for identifying molecular and pharmacological […]
Injury-induced CTE-like pathology emerges in a human multicellular in vitro brain model and reveals mitochondrial and neurovascular regulation
Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease linked to repetitive mild head impacts, but no human-based experimental system exists to study injury-induced CTE-like pathology. Here, we establish a long-lived, human multicellular in vitro brain platform in which controlled mechanical injury induces key cellular features of CTE-like pathology. Injured cultures developed persistent tau phosphorylation, […]
Potential Role of Serum Cytokines and Chemokines as Biomarkers of Injury Severity and Functional Outcomes Following Pediatric Traumatic Brain Injury
Traumatic brain injury (TBI) is one of the leading causes of death and neurological disability worldwide. The search for biomarkers that indicate TBI severity and prognosis with greater accuracy is ongoing. This study aimed to evaluate the significance of several neuroinflammatory cytokines and chemokines, assessing their potential as biomarkers in pediatric TBI (pTBI). This was […]
Biomarkers
CONCLUSION: These findings highlight the potential of AEV-derived inflammatory and complement proteins as biomarkers of neuroinflammation and cognitive decline in TBI-exposed aging populations. The persistence of inflammatory abnormalities in AEVs years after TBI suggests a chronic neuroinflammatory response that may underlie increased AD risk. Future work will examine interactions between inflammatory and neurodegenerative AEV biomarkers […]