Tag:

biomarkers

Traumatic brain injury
PACAP a mediator of inflammation following trauma exposure and mild traumatic brain injury: Differential effects in males and females

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Overview of PACAP and Inflammation Pituitary adenylate cyclase-activating polypeptide (PACAP) is a neuropeptide that plays …

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Traumatic brain injury
Associations of Collegiate Football Career and Incident Concussion with Players’ Health: A Longitudinal Study from the CARE Consortium

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Background and Rationale In recent years, the growing concern surrounding sports-related concussions has prompted educators, …

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Traumatic brain injury
On-Field Diagnosis and Management of Sports-Related Concussion in Pediatric Athletes

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Understanding Concussion in Pediatric Athletes Concussions are a form of traumatic brain injury that occur …

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Stroke
Proteome-Wide Genetic Study in East Asians and Europeans Identified Multiple Therapeutic Targets for Ischemic Stroke

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Genetic Insights into Ischemic Stroke Ischemic stroke, a condition where blood flow to the brain …

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Functional neurological disorders
Autoimmune psychosis: Psychopathological patterns and outcome after immunotherapy

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Autoimmune Psychosis Overview Autoimmune psychosis is an emerging area of interest in neurology and psychiatry, …

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Functional neurological disorders
Neuroimaging Biomarkers of Post-acute Sequelae of Covid (PASC)

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Neuroimaging Techniques and PASC Neuroimaging techniques have emerged as powerful tools in understanding the neurological …

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Functional neurological disorders
Silencer variants are key drivers of gene upregulation in Alzheimer’s disease

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Silencer Variants and Gene Regulation Recent advancements in genetic research have shed light on the …

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Functional neurological disorders
Regulation of chronic neuroinflammation through dietary herbal products

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Role of Dietary Herbal Products in Neuroinflammation Dietary herbal products have garnered significant interest in …

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Headaches
Efficacy, safety, and tolerability of chenodeoxycholic acid (CDCA) in adult patients with cerebrotendinous xanthomatosis (RESTORE): a randomized withdrawal, double-blind, placebo-controlled, crossover phase 3 study

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Efficacy of Chenodeoxycholic Acid Chenodeoxycholic acid (CDCA) has emerged as a critical therapeutic option for …

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Stroke
Increased Risk of Myocardial Infarction in Inclusion Body Myositis: A Non-Concurrent Cohort Study

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Cardiovascular Risk Factors in Inclusion Body Myositis The relationship between inclusion body myositis (IBM) and …

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Cerebral Haemodynamic Assessment Following Sport-related Concussion (Mild Traumatic Brain Injury) in Youth and Amateur Rugby Union Players
CONCLUSION: Current GRTP protocols alone are problematic and there is a need for a more individualised approach to concussion management, utilising objective biomarker tools such as fNIRS.
Systematic vitamin K antagonist reversal with prothrombin complex concentrate in patients with mild traumatic brain injury: randomized controlled trial
CONCLUSION: In patients with recent mild-TBI receiving a VKA, systematic prompt reversal with 4f-PCC did not statistically significantly reduce ICH rate at 24 h. However, the study was prematurely stopped and does not exclude a clinically relevant benefit of the strategy tested.
Echoes of the Battlefield: Five-Year Longitudinal Cognitive Trajectories show Trend of Recovery for Deployment-related mild TBI in the LIMBIC-CENC Cohort
CONCLUSION: The findings suggest that deployment-related mild TBI and PTSD are associated with cognitive performance over time. However, results more importantly demonstrate general improvement of cognitive function in individuals with PTSD or TBI history. This is encouraging and supports an overall trajectory of recovery, rather than brain health decline.
Disclosure of possible concussions in National Rugby League Women's Premiership players
CONCLUSION: We found high rates of non-disclosure amongst NRLW players, which is inconsistent with previous research suggesting that women are more aware of their symptoms than men and more likely to disclose their concussions. Not wanting to be ruled out of the game or training session and being unsure if the symptoms were related to […]
Early Venous Thromboembolism Prophylaxis in Brain Injury Guidelines 1 and Brain Injury Guidelines 2 Traumatic Brain Injury Patients: A 5-Year Analysis
CONCLUSION: Early thromboprophylaxis for BIG 1 or BIG 2 trauma patients is safe and associated with reducing DVT risk without increasing risk of ICH progression or mortality. Future studies are needed to validate thromboprophylaxis risk-benefit ratio among BIG 1 and BIG 2 patients.