Tag:

biomarkers

Functional neurological disorders
Aggressive and Refractory Attack of AQP4-IgG-Positive Neuromyelitis Optica Spectrum Disorder Treated With Ravulizumab: A Case Report

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Clinical Presentation and Diagnosis In this case report, the patient presented with symptoms characteristic of …

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Movement Disorders
EFNB3 Frameshift Variant in Weimaraner Dogs with a Condition Resembling a Congenital Mirror Movement Disorder

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Genetic Background of EFNB3 The EFNB3 gene encodes a protein belonging to the ephrin family, …

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Headaches
Clinical characteristics and efficacy of intrathecal therapy in pediatric lupus encephalopathy

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Clinical Presentation and Diagnosis Pediatric lupus encephalopathy, often associated with systemic lupus erythematosus (SLE), manifests …

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Traumatic brain injury
Prevalence of low scores in the Uniform Data Set version 3.0: Comparison of older adults with and without a self-reported history of traumatic brain injury

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Study Overview This study investigates the occurrence of low scores within the Uniform Data Set …

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Traumatic brain injury
Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Role of Lactate Metabolism in Astrocytes Lactate metabolism plays a pivotal role in cellular energy …

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Movement Disorders
Reduced orthodontic tooth movement in Ank knockout mice

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Investigating Ank Knockout Mice Research into the role of the ANK protein in orthodontics has …

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Traumatic brain injury
Genome-wide analysis of lncRNA m6A methylation in the mouse cortex after repetitive mild traumatic brain injury

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Background on lncRNA and m6A Methylation Long non-coding RNAs (lncRNAs) are an intriguing class of …

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Traumatic brain injury
Blood-Based Biomarkers for Improved Characterization of Traumatic Brain Injury: Recommendations from the 2024 National Institute for Neurological Disorders and Stroke Traumatic Brain Injury Classification and Nomenclature Initiative Blood-Based Biomarkers Working Group

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Biomarker Identification and Validation The identification and validation of biomarkers for traumatic brain injury (TBI) …

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Functional neurological disorders
Modulating autism spectrum disorder pathophysiology using a trace amine-focused approach: targeting the gut

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Trace Amines and Gut-Brain Interaction Trace amines are a class of biogenic amines that, while …

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Functional neurological disorders
HSD17B1-mediated trophoblast differentiation lowers estrogen levels in early-onset preeclampsia

by myneuronews May 20, 2025

by myneuronews May 20, 2025

HSD17B1 Role in Trophoblast Differentiation The study of HSD17B1 (Hydroxysteroid Dehydrogenase Type 1) highlights its …

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Impact of COVID-19 on Guillain Barre Syndrome (GBS) insights from an Iranian referral center
Study Overview The research focused on the implications of COVID-19 on individuals diagnosed with Guillain-Barré…
Evaluation of the Accuracy of a Mechanical Insufflation-Exsufflation Device’s Cough Peak Flow Measurement
Study Overview The study focused on assessing the accuracy of a mechanical insufflation-exsufflation device, which…
Beta-blocker interruption effects on blood pressure and heart rate after myocardial infarction: the AβYSS trial
Study Rationale The decision to investigate the effects of beta-blocker interruption following a myocardial infarction…
Clinical characteristics and efficacy of intrathecal therapy in pediatric lupus encephalopathy
Clinical Presentation and Diagnosis Pediatric lupus encephalopathy, often associated with systemic lupus erythematosus (SLE), manifests…
EFNB3 Frameshift Variant in Weimaraner Dogs with a Condition Resembling a Congenital Mirror Movement Disorder
Genetic Background of EFNB3 The EFNB3 gene encodes a protein belonging to the ephrin family,…

Behavioral, non-pharmacological intervention modalities to alleviate persistent headache attributable to traumatic brain injury: A systematic review of patient pain outcomes in the context of the mutual maintenance model
BackgroundPersistent post-traumatic headache (PPTH) is a disabling sequela of traumatic brain injury (TBI). Many individuals seek behavioral interventions to supplement pharmacological treatment. This systematic review describes behavioral interventions for treatment of PPTH and psychosocial factors related to outcomes in adults.MethodsA systematic search for behavioral interventions for adult patients who suffered headache attributable to mild TBI […]
The experiences and perspectives of participating in a nature integrative rehabilitation programme when suffering from post-concussion syndrome: responses, gains, and impact from using enriched nature environments as a rehabilitation setting and integrating nature as rehabilitation means
CONCLUSIONS: NIR supports individuals with PCS by enhancing emotional well-being, reducing symptoms, and providing coping strategies. Alongside social support, the flexibility of the activities, allowing individuals to engage according to their symptoms and capabilities, is critical for rehabilitative outcomes. Future research should explore long-term effects and refine intervention protocols for implementation in the healthcare system […]
Cost-effectiveness of Cerebrolysin as an add-on treatment for neurorecovery after traumatic brain injury
Traumatic brain injuries (TBIs) are a leading cause of death and long-term disability worldwide, with incidence and injury mechanisms varying by age group and region. Impairment of functional status, diagnoses of anxiety and depression are encountered post-TBI. Studies have shown that Cerebrolysin can have positive effects among TBI survivors. We conducted a cost-effectiveness analysis (CEA) […]
Subjective cognitive functioning in adults hospitalized after traumatic brain injury: A four-year follow-up
CONCLUSIONS: The results suggest that subjective cognitive functioning is poorer than normative values and fairly stable over four years after TBI, with a slight decrease between 4 and 24-36 months, and is similar between mild and moderate-severe TBI.
Mild Traumatic Brain Injury Impairs Fear Extinction and Network Excitability in the Infralimbic Cortex
Traumatic brain injury (TBI) is a leading cause of morbidity and disability, with mild TBI (concussions) representing over 80% of cases. Although often considered benign, mild TBI is associated with persistent neuropsychiatric conditions, including post-traumatic stress disorder, anxiety, and depression. A hallmark of these conditions is impaired fear extinction (FE), the process by which learned […]