Tag:

biomarkers

Functional neurological disorders
Structural insights into heterohexameric assembly of epilepsy-related ligand-receptor complex LGI1-ADAM22

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Structural Characterization of LGI1-ADAM22 Complex The LGI1-ADAM22 complex plays a pivotal role in the synaptic …

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Functional neurological disorders
Development of a novel liquid chromatography-tandem mass spectrometry based enzymatic assay of 5,10-methylenetetrahydrofolate reductase

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Enzymatic Assay Development The development of a novel enzymatic assay for 5,10-methylenetetrahydrofolate reductase (MTHFR) taps …

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Traumatic brain injury
Biomarker evidence of neurodegeneration in mid-life former rugby players

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Neurodegeneration Biomarkers Biomarkers indicative of neurodegeneration are crucial for understanding the underlying processes affecting brain …

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Traumatic brain injury
Brain health concerns in former rugby players: clinical and cognitive phenotypes

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Context of Brain Health in Rugby The discussion around brain health in former rugby players …

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Traumatic brain injury
The chronic aftermath of recurrent intimate partner violence-related brain injuries: Insights from rat models of traumatic brain injury and non-fatal strangulation

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Research Framework The exploration of recurrent intimate partner violence (IPV) and its effects on brain …

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Movement Disorders
Distinct 11C-ER176 PET Neuroinflammatory Profiles and Tau Colocalization in Progressive Apraxia of Speech With and Without Parkinson-plus Syndrome

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Study Overview The research focuses on the complex relationship between neuroinflammation and tau pathology in …

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Traumatic brain injury
Pediatric Mild Traumatic Brain Injury and Concussion

by myneuronews June 28, 2025

by myneuronews June 28, 2025

Understanding Mild Traumatic Brain Injury in Pediatric Patients Pediatric mild traumatic brain injury (mTBI), commonly …

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Traumatic brain injury
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Clinical Phenotypes In chronic traumatic brain injury (TBI), individuals often manifest a variety of clinical …

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Dementia
Uncovering Putative Causal Non-Coding RNAs in Acute and Chronic Myeloid Leukemia: A Genome-Wide Mendelian Randomization Study

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The investigation aimed to explore the role of non-coding RNAs in the development …

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Stroke
The effects of radiation therapy on the brain: implications for management

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Effects of Radiation Therapy on Brain Function Radiation therapy, a common treatment modality for various …

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Controversies in the diagnosis of chronic inflammatory demyelinating polyneuropathy
Understanding Chronic Inflammatory Demyelinating Polyneuropathy Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is characterized by a progressive…
Interferon alfa and beta receptor confers resistance against Neospora caninum infection in mice
Study Overview This investigation focuses on the interaction between interferon-alfa and -beta receptors and their…
Advances and challenges in experimental models of posttraumatic epilepsy for therapeutic interventions
Experimental Models of Posttraumatic Epilepsy Research into posttraumatic epilepsy (PTE) has benefited significantly from various…
Anti-NMDA receptor encephalitis following SARS-CoV-2 infection in children
Study Overview The study investigates the neurological complications associated with anti-NMDA receptor encephalitis in pediatric…
Insights From a Mixed Methods Analysis of 3 Health Technologies Used in Patients With Parkinson Disease: Mixed Methods Study
Study Overview The research presented a comprehensive examination of three distinct health technologies utilized by…

Interpreting Change in Sport Concussion Assessment Tool-5th Edition (SCAT5) Scores in National Rugby League Women's Premiership Players
CONCLUSION: SCAT5 scores had low to moderate test-retest reliability across a one-year period. Reliable change scores for the SCAT5 were developed in this study for use with professional women rugby league players. When evaluating post-injury SCAT5 scores, it can be helpful to consider both what the score means compared to normative reference values and compared […]
An update on paediatric traumatic brain injury in the emergency department: a narrative review
Traumatic brain injury (TBI) affects an estimated 330,000 to 500,000 children annually in England and Wales and represents a significant burden on healthcare systems. Presentations range from mild to severe, and each case presents unique challenges to the Emergency Department (ED) clinicians. Most paediatric TBIs are mild, and several validated clinical decision rules (CDRs) such […]
The effect of neck strength and anthropometric properties on the linear and rotational accelerations experienced by academy footballers during heading: an exploratory analysis
CONCLUSION: Neck strength and anthropometric factors showed mixed associations with head accelerations during heading, explaining a small proportion of the variance in linear and rotational accelerations.
Ultra-early detection of S100B biomarkers using a nanophotonic biosensor with deep learning quantification: A clinical model based on EDAS patients
CONCLUSION: This biosensor-AI platform enables rapid (
An Analysis of Guardian Cap Use and Changes in the Concussion Rate in National Football League Preseason Practices From 2018 to 2023
CONCLUSION: Required use of the Guardian Cap NXT was associated with a 54% to 62% reduction in the overall incidence of NFL practice concussions. However, when only concussions involving a helmet shell impact were considered, there was no longer a significant relationship between Guardian Cap NXT use and the incidence of concussions.