Tag:

biomarkers

Functional neurological disorders
Fluid Biomarkers in Demyelinating Spectrum Disorders: Past, Present, and Prospects

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Fluid Biomarker Applications in Demyelinating Disorders Fluid biomarkers play a crucial role in the diagnosis …

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Traumatic brain injury
Correction: Cerebral Haemodynamic Assessment Following Sport-related Concussion (Mild Traumatic Brain Injury) in Youth and Amateur Rugby Union Players

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Cerebral haemodynamics in concussion Cerebral haemodynamics refers to the dynamics of blood flow within the …

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Functional neurological disorders
Research Progress on BDNF and Depression

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Understanding BDNF’s Role in Depression Brain-derived neurotrophic factor (BDNF) is a protein that plays a …

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Dementia
Validating the Amyloid Cascade Through the Revised Criteria of Alzheimer’s Association Workgroup 2024 for Alzheimer Disease

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Amyloid Cascade Hypothesis and Alzheimer Disease The Amyloid Cascade Hypothesis is a prominent concept in …

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Dementia
Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer’s Disease

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Treatment Strategy Overview In recent years, the exploration of innovative approaches to treat Alzheimer’s disease …

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Functional neurological disorders
Association of type 1 stiff-person syndrome and insulinoma: a case report and narrative review

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Clinical Presentation and Diagnosis The clinical presentation of type 1 stiff-person syndrome (SPS) characterized by …

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Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological Tau Phosphorylation Mechanisms Tau protein is a key player in maintaining the structural integrity …

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Traumatic brain injury
A systematic review and meta-analysis of sleep following mild traumatic brain injury: A synthesis of the literature according to age and time-since-injury

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Effect of Age on Sleep Post-Injury The relationship between age and sleep disturbances following a …

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Dementia
Unraveling sex differences in Alzheimer’s disease and related endophenotypes with brain proteomes

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Research Context The study of Alzheimer’s disease (AD) has gained considerable momentum as researchers explore …

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Movement Disorders
The prodromal individuals’ perspective on active recruitment for early detection of α-synucleinopathies

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Perspective of Prodromal Individuals The perspective of individuals in the prodromal stage of α-synucleinopathies sheds …

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Effectiveness of disease-modifying agents in ameliorating multiple sclerosis – A cross-sectional observational study
Study Overview This research was designed to assess the efficacy of disease-modifying agents (DMAs) in…
Systemic Neisseria sicca Infection Associated With Ravulizumab Therapy in Myasthenia Gravis
Study Overview The research focuses on the implications of Ravulizumab therapy in patients suffering from…
Aortic stenosis intricacies beyond the valve: A bidirectional Mendelian randomization study
Study Overview This study explores the multifaceted relationships surrounding aortic stenosis, a condition characterized by…
Effectiveness of Instrument-assisted Soft-tissue Mobilization Versus Dry Cupping on Pain and Cervical Range of Motion in Treatment of Neck Pain
Study Overview The research compares two therapeutic techniques, instrument-assisted soft tissue mobilization (IASTM) and dry…
Metabolic abnormalities of the cortico‑striato‑thalamo‑cortical circuit of rats with tic disorder
Metabolic Alterations in Tic Disorders Research into tic disorders has revealed significant metabolic changes that…

The Use of Technology to Support Cognitive Diversity Among Older Adults
Older adults represent a remarkably heterogeneous population that is diverse in many dimensions, including cognition. Cognitive diversity includes normative age-related changes in cognition, mild cognitive impairment (MCI), and more severe impairments such as dementia. The causes and nature of these cognitive impairments (CIs) are varied, extending beyond MCI and Alzheimer's disease and related dementias to […]
Subsequent Emergency Department Visits in Geriatric Mild Traumatic Brain Injury: Relationship with Fall, Payor, and Discharge Outcome
Background/Objectives: Older adults (ages ≥ 65) have experienced longer recovery, decreased independence in self-care, and reduced quality of life after diagnosis of mild traumatic brain injury (mTBI). Although the sequela following mTBI has also generated higher healthcare costs in older adults, the research on associations returning to the emergency department (ED) has been limited. This […]
Depression Symptoms Associated With Clinical Symptoms, Disability, and Functional Connectivity After Traumatic Brain Injury
CONCLUSIONS: The findings suggest that depression after TBI may not be a unitary syndrome but rather may be composed of clusters of symptoms that have different associations with TBI symptom burden, disability, and brain connectivity.
Resting-State Brain Activity Changes and Their Genetic Correlates in Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) often leads to persistent cognitive and emotional symptoms, but the underlying neurobiological mechanisms remain unclear. Although previous studies have reported alterations in resting-state brain activity in mTBI patients, the findings have been inconsistent, and the genetic basis of these changes has not been fully explored. A coordinate-based voxel-wise meta-analysis was […]
The Polytrauma Clinical Triad Among Women with a History of Intimate Partner Violence
Women with a history of intimate partner violence (IPV) are at risk for traumatic brain injury (TBI) with persistent neurobehavioral symptoms, post-traumatic stress disorder (PTSD), and chronic pain, which, together, characterize the polytrauma clinical triad. Among predominantly male Veteran samples, research has suggested that the triad may exacerbate health problems, compared with the presence of […]