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biomarkers

Traumatic brain injury
Pain Management in Mild Traumatic Brain Injury: Central Sensitization as a Multispecialty Challenge

by myneuronews June 4, 2025

by myneuronews June 4, 2025

Understanding Central Sensitization Central sensitization is a crucial phenomenon related to the heightened sensitivity to …

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Traumatic brain injury
High-resolution segmentation of the cavum septum pellucidum in young adult human brains

by myneuronews June 4, 2025

by myneuronews June 4, 2025

High-Resolution Imaging Techniques The study of the cavum septum pellucidum (CSP) in young adult human …

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Dementia
Cognitive decline in an adult with ATR-16 syndrome due to an unbalanced translocation between 11p15.5 and 16p13.3: a case report

by myneuronews June 3, 2025

by myneuronews June 3, 2025

Case Presentation This case involves a 32-year-old female patient diagnosed with ATR-16 syndrome, which manifests …

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Movement Disorders
[18F]FE-PE2I PET is a diagnostic tool in dementia with Lewy bodies

by myneuronews June 3, 2025

by myneuronews June 3, 2025

Diagnostic Efficacy The application of 18F]FE-PE2I PET imaging has shown promise as a valuable diagnostic …

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Functional neurological disorders
Microglia-drive IRF8 upregulates complement pathway in Parkinson’s disease

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Microglia and Parkinson’s Disease Pathophysiology Microglia, the resident immune cells of the central nervous system, …

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Traumatic brain injury
Abstracts of the 5th Annual Meeting of the Canadian Concussion Network/Reseau Canadien des Commotions (CCN-RCC)

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Study Overview The 5th Annual Meeting of the Canadian Concussion Network (CCN-RCC) gathered researchers, healthcare …

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Functional neurological disorders
Loss of CD98HC phosphorylation by ATM impairs antiporter trafficking and drives glutamate toxicity in Ataxia telangiectasia

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Loss of CD98HC Phosphorylation and Its Consequences Recent research has highlighted the significant role of …

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Functional neurological disorders
Microglia-drive IRF8 upregulates complement pathway in Parkinson’s disease

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Microglia and Their Role in Parkinson’s Disease Microglia are specialized immune cells in the central …

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Functional neurological disorders
Spatial navigation entropy suggests allocentric dysfunction in PPPD

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Spatial Navigation and Its Importance Spatial navigation is a fundamental cognitive ability that allows individuals …

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Traumatic brain injury
Sex-dependent blood-brain barrier alterations following repeated mild blast traumatic brain injury at varying inter-injury intervals

by myneuronews June 1, 2025

by myneuronews June 1, 2025

Study Overview The investigation focused on the impact of repeated mild blast traumatic brain injuries …

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Influence of Social Determinants of Health on Treatment Completion for Pediatric Mild Traumatic Brain Injury in a Safety Net Hospital
The negative impact of the Social Determinants of Health (SDOH) on health care outcomes in vulnerable populations, particularly pediatric patients, is a well-established phenomenon. The treatment of traumatic brain injury is not an exception. It is not clear, however, which specific social determinants of health factor is more influential on the current management of traumatic […]
Altered autonomic cardiovascular function in adults with persisting post-concussive symptoms and exercise intolerance
Alterations in autonomic cardiovascular function may result following mild traumatic brain injury (mTBI), but there is a lack of data evaluating autonomic function in adults with persisting post-concussive symptoms (PPCS). We collected resting measures of heart rate (HR), heart rate variability (HRV), blood pressure (BP) and cardiac baroreceptor sensitivity in 50 adults with PPCS (42.8 […]
Comparison of Machine Learning Models in Predicting Mental Health Sequelae Following Concussion in Youth
Youth who experience concussions may be at greater risk for subsequent mental health challenges, making early detection crucial for timely intervention. This study utilized Bidirectional Long Short-Term Memory (BiLSTM) networks to predict mental health outcomes following concussion in youth and compared its performance to traditional models. We also examined whether incorporating social determinants of health […]
Inhibition of p38 MAPK after repetitive mild TBI ameliorates immune signaling and behavioral deficits
BACKGROUND: Mild traumatic brain injury (mTBI) can cause long-term functional impairments, and repetitive mTBIs within a window of vulnerability can exacerbate these consequences compared to a single mTBI. However, current interventions for mTBI focus on alleviating symptoms, rather than targeting underlying mechanisms. Following the initial mechanical impact, increasing evidence suggests that the brain undergoes an […]
Management of sports-related concussion - a stepwise rehabilitation protocol
Early recognition and management of sports-related concussion (SRC), including removal from the sports activity, is essential for player safety and to prevent long-term symptoms. A graduated, stepwise rehabilitation protocol is implemented to allow the athlete to return to sports. In 2022, the 6th international consensus statement on concussion in sports was presented, which has now […]