External validation of KFLC index threshold for multiple sclerosis diagnosis in a French cohort
Study Overview This research aims to assess the performance of the KFLC index threshold in diagnosing multiple sclerosis (MS) within […]
Anti-MAG Neuropathy: Disease Overview, Gait Characteristics, and Rehabilitation Needs
Disease Mechanism and Pathophysiology Anti-MAG neuropathy is characterized by the presence of anti-myelin-associated glycoprotein (MAG) antibodies, which play a critical
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External validation of KFLC index threshold for multiple sclerosis diagnosis in a French cohort
Study Overview The research focused on the KFLC (kappa free light chain) index and its application as a biomarker in
Anti-MAG Neuropathy: Disease Overview, Gait Characteristics, and Rehabilitation Needs
Disease Mechanism Anti-MAG neuropathy is characterized by the presence of antibodies against myelin-associated glycoprotein (MAG). These antibodies result in a
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Decoding the PI3K/Akt/mTOR-JAK/STAT signaling axis in multiple sclerosis: mechanistic crosstalk and therapeutic opportunities
Mechanistic Pathways of PI3K/Akt/mTOR and JAK/STAT The interplay between the PI3K/Akt/mTOR and JAK/STAT signaling pathways plays a crucial role in
TREM2 in neurodegenerative diseases and acute neurological injuries: mechanisms to targeted therapies
Trem2 Function in Neurodegenerative Diseases TREM2, or Triggering Receptor Expressed on Myeloid Cells 2, plays a crucial role in the
A qualitative approach to extract diagnostic patterns of cognitive impairment in Parkinson’s disease
Diagnostic Patterns in Parkinson’s Disease In individuals with Parkinson’s disease (PD), cognitive impairment can manifest in various ways, leading to
Gut microbiota and gut-derived metabolites in defining multiple sclerosis phenotypic continuum
Gut Microbiota Role The gut microbiota plays a fundamental part in maintaining human health, impacting various physiological processes through the
FcRn inhibitors in the treatment of CIDP
FcRn Inhibitors Mechanism of Action FcRn inhibitors target the neonatal Fc receptor (FcRn), a crucial protein responsible for regulating the
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Characterizing functional connectivity alterations in functional/ dissociative seizures using resting-state and naturalistic fMRI
Study Overview This research investigates the alterations in brain connectivity associated with functional and dissociative seizures, focusing specifically on how