Tag:

biomarkers

Headaches
Intranasal Empagliflozin Modulates Synaptic Plasticity in Migraine: Insights into Calcium Signaling and Epigenetic Regulation

by myneuronews August 31, 2025

by myneuronews August 31, 2025

Mechanisms of Action Empagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor, primarily functions by reducing glucose …

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Traumatic brain injury
Recurrent spaced concussions in adolescent rats disrupt cortical dopaminergic markers and induce behavioral hyperactivity and impaired object location memory

by myneuronews August 31, 2025

by myneuronews August 31, 2025

Study Overview The study investigates the effects of recurrent concussions on brain chemistry and behavior …

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Functional neurological disorders
Functional/dissociative seizures: Proposal for a new diagnostic label and definition by the ILAE task force

by myneuronews August 30, 2025

by myneuronews August 30, 2025

Functional Seizures Overview Functional seizures, also referred to as non-epileptic seizures or dissociative seizures, represent …

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Traumatic brain injury
Associations between traumatic brain injury and the prevalence of Alzheimer’s disease dementia and behavioral and psychological symptoms of dementia: A retrospective cohort study

by myneuronews August 29, 2025

by myneuronews August 29, 2025

Associations between TBI and Alzheimer’s Disease Traumatic brain injury (TBI) has garnered significant interest as …

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Traumatic brain injury
Chronic traumatic encephalopathy

by myneuronews August 29, 2025

by myneuronews August 29, 2025

Pathophysiology of Chronic Traumatic Encephalopathy Chronic traumatic encephalopathy (CTE) is a neurodegenerative condition associated with …

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Functional neurological disorders
Comorbidities Across Functional Neurological Disorder Subtypes: A Comprehensive Narrative Synthesis

by myneuronews August 28, 2025

by myneuronews August 28, 2025

Comorbidities in Functional Neurological Disorder Comorbidities associated with Functional Neurological Disorder (FND) present a complex …

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Functional neurological disorders
Management of Functional Neurological Disorder

by myneuronews August 28, 2025

by myneuronews August 28, 2025

Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) presents a unique challenge within the field …

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Functional neurological disorders
Management of Functional Neurological Disorder

by myneuronews August 28, 2025

by myneuronews August 28, 2025

Overview of Functional Neurological Disorder Functional Neurological Disorder (FND) manifests as a group of neurological …

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Functional neurological disorders
Comorbidities Across Functional Neurological Disorder Subtypes: A Comprehensive Narrative Synthesis

by myneuronews August 28, 2025

by myneuronews August 28, 2025

Comorbidity Patterns in Functional Neurological Disorder In the realm of Functional Neurological Disorder (FND), the …

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Functional neurological disorders
Functional Neurological Disorder: A Case of Twisted Toes and Dystonia

by myneuronews August 27, 2025

by myneuronews August 27, 2025

Clinical Presentation and Symptoms The clinical presentation of Functional Neurological Disorder (FND) can be exceptionally …

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Severe Headache in a Child With Rickettsial Infection: A Case Report
Case Presentation A previously healthy 10-year-old boy was brought to the pediatric emergency department due…
Polygenic risk score of Alzheimer’s disease is associated with cognitive trajectories and phenotypes of cerebral organoids
Study Overview This study investigates the relationship between polygenic risk scores (PRS) for Alzheimer’s disease…
How Neurologists Combine Clinical Signs and Subjective Factors to Diagnose Epileptic and Functional Seizures: Insights From Seizure Video Analysis
Diagnostic Approaches in Epilepsy and Seizures The diagnosis of epilepsy and seizures is a complex…
Active Rehabilitation Following Acute Mild Traumatic Brain Injury: A Systematic Review
Active Rehabilitation Approaches Active rehabilitation is a crucial component in the recovery process following an…
Connecting the Dots: The Role of Pediatric Concussion on Pubertal Hormones and Psychological Health
Pediatric Concussions: Overview and Impact Pediatric concussions are a significant public health concern, with increasing…

The cumulative effects of a collegiate athletic career on general health measures: findings from the CARE Consortium
CONCLUSIONS: Lifetime concussion history is associated with self-reported health outcomes at institutional-exit, though small effect sizes suggest limited clinical consequence. Higher contact-exposure sports and increased YoP were associated with improved scores on some clinical measures. Further longitudinal monitoring is encouraged to evaluate health-related changes over time, to support student-athletes as they transition out of collegiate […]
Symptoms of Allodynia and Pain Thresholds Amongst Those with Acute Post-Traumatic Headache Attributed to Mild Traumatic Brain Injury: A Prospective, Longitudinal Study
Background Post-traumatic headache (PTH) is a common acute and persistent symptom following mild traumatic brain injury (mTBI). Symptoms of cutaneous allodynia and presence of nociceptive sensitization might be associated with acute PTH and its persistence. The objectives of this study were to compare allodynia symptoms and cutaneous heat pain thresholds amongst males and females with […]
Efficacy of Methylphenidate in Patients With Brain Disease: A Systematic Review and Meta-Analysis
This systematic review and meta-analysis evaluated the efficacy and safety of methylphenidate in patients with brain disease. A comprehensive search up to November 4, 2024 identified 33 randomized controlled trials involving 1,369 participants with traumatic brain injury (TBI), stroke, Parkinson's disease (PD), Alzheimer's disease (AD), other dementias, and multiple sclerosis. Methylphenidate was administered at 10-80 […]
Blast-Related Mild Traumatic Brain Injury: Case Report Highlighting the Long-Term Neurocognitive Sequelae Following Blast Exposure in Veterans
Traumatic brain injury (TBI) remains a significant public health concern, particularly among military service members exposed to blast-related trauma. While mild TBIs often resolve within weeks, a subset of patients may experience lifelong, persistent, debilitating symptoms. We report a case of a previously healthy male combat medic who sustained a blast-related traumatic brain injury during […]
Smooth Pursuit Velocity After a Season of Repetitive Head Impacts in American Football Players
CONCLUSIONS AND RELEVANCE: In this study, smooth pursuit eye movement velocity was not affected during a single season of contact sports. Group differences suggest existing deficits before the season begins, possibly due to prior contact sport history. Interpretations should be tempered by the small sample size, single institution used for data collection, and the exploratory […]