Tag:

biomarkers

Functional neurological disorders
DG9 boosts PMO nuclear uptake and exon skipping to restore dystrophic muscle and cardiac function

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Mechanisms of DG9 Action DG9 has emerged as a pivotal compound in the realm of …

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Functional neurological disorders
Progress in the Management of Mediastinal Ectopic Parathyroid Adenomas: The Role of Minimally Invasive Surgery

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Advancements in Minimally Invasive Techniques In recent years, there has been an impressive evolution in …

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Functional neurological disorders
Fluid Biomarkers in Demyelinating Spectrum Disorders: Past, Present, and Prospects

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Fluid Biomarker Applications in Demyelinating Disorders Fluid biomarkers play a crucial role in the diagnosis …

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Traumatic brain injury
Correction: Cerebral Haemodynamic Assessment Following Sport-related Concussion (Mild Traumatic Brain Injury) in Youth and Amateur Rugby Union Players

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Cerebral haemodynamics in concussion Cerebral haemodynamics refers to the dynamics of blood flow within the …

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Functional neurological disorders
Research Progress on BDNF and Depression

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Understanding BDNF’s Role in Depression Brain-derived neurotrophic factor (BDNF) is a protein that plays a …

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Dementia
Validating the Amyloid Cascade Through the Revised Criteria of Alzheimer’s Association Workgroup 2024 for Alzheimer Disease

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Amyloid Cascade Hypothesis and Alzheimer Disease The Amyloid Cascade Hypothesis is a prominent concept in …

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Dementia
Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer’s Disease

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Treatment Strategy Overview In recent years, the exploration of innovative approaches to treat Alzheimer’s disease …

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Functional neurological disorders
Association of type 1 stiff-person syndrome and insulinoma: a case report and narrative review

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Clinical Presentation and Diagnosis The clinical presentation of type 1 stiff-person syndrome (SPS) characterized by …

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Traumatic brain injury
Cellular and molecular mechanisms of pathological tau phosphorylation in traumatic brain injury: implications for chronic traumatic encephalopathy

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Pathological Tau Phosphorylation Mechanisms Tau protein is a key player in maintaining the structural integrity …

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Traumatic brain injury
A systematic review and meta-analysis of sleep following mild traumatic brain injury: A synthesis of the literature according to age and time-since-injury

by myneuronews May 10, 2025

by myneuronews May 10, 2025

Effect of Age on Sleep Post-Injury The relationship between age and sleep disturbances following a …

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Impact of COVID-19 on Guillain Barre Syndrome (GBS) insights from an Iranian referral center
Study Overview The research focused on the implications of COVID-19 on individuals diagnosed with Guillain-Barré…
Evaluation of the Accuracy of a Mechanical Insufflation-Exsufflation Device’s Cough Peak Flow Measurement
Study Overview The study focused on assessing the accuracy of a mechanical insufflation-exsufflation device, which…
Beta-blocker interruption effects on blood pressure and heart rate after myocardial infarction: the AβYSS trial
Study Rationale The decision to investigate the effects of beta-blocker interruption following a myocardial infarction…
Clinical characteristics and efficacy of intrathecal therapy in pediatric lupus encephalopathy
Clinical Presentation and Diagnosis Pediatric lupus encephalopathy, often associated with systemic lupus erythematosus (SLE), manifests…
EFNB3 Frameshift Variant in Weimaraner Dogs with a Condition Resembling a Congenital Mirror Movement Disorder
Genetic Background of EFNB3 The EFNB3 gene encodes a protein belonging to the ephrin family,…

Behavioral, non-pharmacological intervention modalities to alleviate persistent headache attributable to traumatic brain injury: A systematic review of patient pain outcomes in the context of the mutual maintenance model
BackgroundPersistent post-traumatic headache (PPTH) is a disabling sequela of traumatic brain injury (TBI). Many individuals seek behavioral interventions to supplement pharmacological treatment. This systematic review describes behavioral interventions for treatment of PPTH and psychosocial factors related to outcomes in adults.MethodsA systematic search for behavioral interventions for adult patients who suffered headache attributable to mild TBI […]
The experiences and perspectives of participating in a nature integrative rehabilitation programme when suffering from post-concussion syndrome: responses, gains, and impact from using enriched nature environments as a rehabilitation setting and integrating nature as rehabilitation means
CONCLUSIONS: NIR supports individuals with PCS by enhancing emotional well-being, reducing symptoms, and providing coping strategies. Alongside social support, the flexibility of the activities, allowing individuals to engage according to their symptoms and capabilities, is critical for rehabilitative outcomes. Future research should explore long-term effects and refine intervention protocols for implementation in the healthcare system […]
Cost-effectiveness of Cerebrolysin as an add-on treatment for neurorecovery after traumatic brain injury
Traumatic brain injuries (TBIs) are a leading cause of death and long-term disability worldwide, with incidence and injury mechanisms varying by age group and region. Impairment of functional status, diagnoses of anxiety and depression are encountered post-TBI. Studies have shown that Cerebrolysin can have positive effects among TBI survivors. We conducted a cost-effectiveness analysis (CEA) […]
Subjective cognitive functioning in adults hospitalized after traumatic brain injury: A four-year follow-up
CONCLUSIONS: The results suggest that subjective cognitive functioning is poorer than normative values and fairly stable over four years after TBI, with a slight decrease between 4 and 24-36 months, and is similar between mild and moderate-severe TBI.
Mild Traumatic Brain Injury Impairs Fear Extinction and Network Excitability in the Infralimbic Cortex
Traumatic brain injury (TBI) is a leading cause of morbidity and disability, with mild TBI (concussions) representing over 80% of cases. Although often considered benign, mild TBI is associated with persistent neuropsychiatric conditions, including post-traumatic stress disorder, anxiety, and depression. A hallmark of these conditions is impaired fear extinction (FE), the process by which learned […]