Tag:

biomarkers

Functional neurological disorders
Investigating Resting-State Brain Activity in Adolescents with High-Functioning Autism Spectrum Disorder: Linking Fractional Amplitude of Low-Frequency Fluctuation to Clinical Symptoms

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Resting-State Brain Activity in Adolescents Resting-state brain activity refers to the spontaneous brain fluctuations that …

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Functional neurological disorders
Mapping neurological symptoms and muscle tension representations in impaired gray matter volume of Wilson disease

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Neurological Symptoms in Wilson Disease Wilson disease, a genetic disorder characterized by excessive copper accumulation …

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Functional neurological disorders
Investigating Resting-State Brain Activity in Adolescents with High-Functioning Autism Spectrum Disorder: Linking Fractional Amplitude of Low-Frequency Fluctuation to Clinical Symptoms

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Resting-State Brain Activity in Adolescents Resting-state brain activity in adolescents, particularly those diagnosed with high-functioning …

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Functional neurological disorders
Mapping neurological symptoms and muscle tension representations in impaired gray matter volume of Wilson disease

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Neurological Symptoms in Wilson Disease Wilson disease is a genetic disorder that leads to excessive …

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Dementia
Identification of diagnostic DNA methylation markers in the blood of Japanese Alzheimer’s disease patients using methylation capture sequencing

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Study Overview The research aimed to uncover specific DNA methylation markers present in the blood …

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Movement Disorders
Identifying kinematic biomarkers of the dystrophic phenotype in a zebrafish model of Duchenne muscular dystrophy

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Kinematic Biomarkers Identification Identifying kinematic biomarkers in the context of Duchenne muscular dystrophy (DMD) is …

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Functional neurological disorders
Neuroglobin: A promising candidate to treat neurological diseases

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Neuroglobin Functionality and Mechanism Neuroglobin, a heme-containing protein predominantly expressed in the brain, plays a …

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Functional neurological disorders
Pain Management Strategies for Patients Receiving Extended-Release Buprenorphine for Opioid Use Disorder: A Scoping Review

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Overview of Pain Management Strategies Pain management in patients receiving extended-release buprenorphine for opioid use …

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Traumatic brain injury
Advances in Circulating Biomarkers for Neurodegenerative Diseases, Traumatic Brain Injuries, and Central Nervous System Tumors

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Advancements in Biomarker Discovery Significant progress has been made in the realm of biomarker discovery, …

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Traumatic brain injury
The Acute Effects of Non-concussive Head Impacts on Brain Microstructure, Chemistry and Function in Male Soccer Players: A Pilot Randomised Controlled Trial

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Study Overview This pilot randomized controlled trial set out to investigate the immediate effects of …

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Aldehydic load as an objective imaging biomarker of mild traumatic brain injury
Mild traumatic brain injury (mTBI) is neurological impairment induced by biomechanical forces without structural brain damage, currently without an objective diagnostic tool. Downstream injury stems from oxidative damage leading to the production of neurotoxic aldehydes. A collagen-based 3D corticomimetic in vitro model of concussion was developed, confirming aldehyde production following impact. Total aldehyde levels were […]
Plasma levels of biomarkers associated with vasodilation and neuroinflammation in pediatric patients with head trauma and their relationship with clinical characteristics of patients
CONCLUSION: Evaluation of pediatric patients with head trauma together with these neuropeptides may provide great benefits in deciding whether to perform radiography such as CT. However, due to the relatively low sensitivities in ROC analysis and small sample size, further studies are warranted before they may be used as a screening test to distinguish CT-positive […]
Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures
Service members and law enforcement personnel are frequently exposed to blast overpressure during training and combat due to the use of heavy weaponry such as large-caliber rifles, explosives, and ordnance. The cumulative effects of these repeated low-level (
Trajectories of fear avoidance behavior and recovery after mild traumatic brain injury: Findings from the Toronto Concussion Study
CONCLUSION: Early fear avoidance behavior often decreases, but when it does not, it is associated with worse recovery from mTBI. These findings may inform the timing and design of interventions targeting fear avoidance behavior in patients with mTBI. (PsycInfo Database Record (c) 2025 APA, all rights reserved).
Proposed Reformulation of Brain Injury Criteria (BrIC) Using Head Rotation-Induced Brain Injury Thresholds Simulated and Derived Directly from A Subhuman Primate Finite Element Model
Recent studies have found that Brain Injury Criteria (BrIC) grossly overpredicts instances of real-world, severe traumatic brain injury (TBI). However, as it stands, BrIC is the leading candidate for a rotational head kinematics-based brain injury criteria for use in automotive regulation and general safety standards. This study attempts to understand why BrIC overpredicts the likelihood […]