Tag:

biomarkers

Functional neurological disorders
Delineating network integration and segregation in the pathophysiology of functional neurological disorder

by myneuronews May 28, 2025

by myneuronews May 28, 2025

Understanding Network Integration in FND Functional Neurological Disorder (FND) represents a complex interplay of psychological …

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Functional neurological disorders
Immune inflammatory regulation in Anti-NMDAR encephalitis: insights from transcriptome analysis

by myneuronews May 26, 2025

by myneuronews May 26, 2025

Immune Mechanisms in Anti-NMDAR Encephalitis Anti-NMDAR encephalitis is characterized by the presence of antibodies that …

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Traumatic brain injury
Response to the Letter to the Editor: “Comments on ‘Acupuncture Treatment for Chronic Post-Traumatic Headache in Individuals with Mild Traumatic Brain Injury: A Pilot Study'”

by myneuronews May 26, 2025

by myneuronews May 26, 2025

Study Overview In recent years, the exploration of acupuncture as a therapeutic option for chronic …

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Functional neurological disorders
Comprehensive Neuropsychological Assessment of Confirmed Xeroderma Pigmentosum a Variant with Neurological Manifestations: Case Report

by myneuronews May 25, 2025

by myneuronews May 25, 2025

Clinical Presentation and Symptoms The case of a patient with xeroderma pigmentosum (XP) confirmed the …

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Functional neurological disorders
Developing a disease-specific accessible transcriptional signature as a biomarker for ataxia with oculomotor apraxia type 2

by myneuronews May 24, 2025

by myneuronews May 24, 2025

Background of Ataxia with Oculomotor Apraxia Type 2 Ataxia with oculomotor apraxia type 2 (AOA2) …

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Functional neurological disorders
Alterations of White Matter Functional Networks in Pediatric Drug-Resistant Temporal Lobe Epilepsy: A Graph Theory Analysis Study

by myneuronews May 24, 2025

by myneuronews May 24, 2025

Alterations in White Matter Networks The study of white matter networks in pediatric patients suffering …

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Functional neurological disorders
A Narrative Review of Pemphigoid Diseases: Bridging Associations, Comorbidities, and Management

by myneuronews May 24, 2025

by myneuronews May 24, 2025

Overview of Pemphigoid Diseases Pemphigoid diseases are a group of rare autoimmune conditions primarily characterized …

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Traumatic brain injury
A new characterisation of acute traumatic brain injury: the NIH-NINDS TBI Classification and Nomenclature Initiative

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Definition and Classification of TBI Traumatic brain injury (TBI) is a complex and multifaceted condition …

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Dementia
Experimental evidence that readily diffusible forms of Aβ from Alzheimer’s disease brain have seeding activity

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Seeding Activity of Aβ Variants The aggregation of amyloid-beta (Aβ) peptides into plaques is a …

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Traumatic brain injury
Exercise plasma improves traumatic brain injury outcomes in mice

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Effects of Exercise Plasma on Brain Injury Research has shown that exercise can have profound …

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Neurotrauma induced retinal basement membrane COL4A1 defects are restored by adipose tissue derived mesenchymal stem cell concentrated conditioned medium
CONCLUSIONS: These findings collectively identify COL4A1 deficiency as a sensitizing factor for post-traumatic visual dysfunction and demonstrate that ASC-CCM exerts therapeutic effects by preserving retinal vascular structure and modulating inflammatory responses, positioning it as a promising candidate for treating TBI-related ocular neurovascular injury.
Hollow CuS nanocubes enhance serum metabolic profiles for rapid diagnosis and severity grading of traumatic brain injury
Traumatic brain injury (TBI) remains a significant global health burden and demands rapid, objective diagnostics that work outside imaging suites and intensive lab workflows. Here, we developed a copper sulfide (CuS) nanocube-assisted laser desorption/ionization mass spectrometry (LDI-MS) platform to acquire serum metabolic profiles (SMPs) with high sensitivity, low background in the low-m/z region, and excellent […]
Attention-Deficit/Hyperactivity Disorder Following Mild Traumatic Brain Injury in Children: A Retrospective Exploratory Study
Introduction This study examines whether attention-deficit/hyperactivity disorder (ADHD) can develop after traumatic brain injury in children. Overlapping acute symptoms can hinder early identification and diagnosis. We investigated whether demographic or acute clinical features are associated with the development of secondary ADHD (S-ADHD) following mild pediatric traumatic brain injury. Materials and methods We conducted a retrospective […]
Ultra-high contrast MRI: a new technique for recognizing secondary changes to the brain in patients with persistent symptoms following traumatic brain injury
CONCLUSION: The whiteout sign was strongly associated with being in the symptomatic group and is a potential biomarker for recognition of secondary changes to the brain in patients with persistent symptoms following TBI.
The risk of all-cause injury and site-specific injury in athletes after concussion: a systematic review and meta-analysis
CONCLUSION: A history of concussion significantly increases the risk of subsequent injuries, with the odds being highest for recurrent concussion. The persistence of this risk beyond six months suggests that clinical recovery does not equate to full functional recovery. These findings underscore the need for enhanced return-to-play protocols that incorporate objective functional assessments and targeted […]