Tag:

biomarkers

Traumatic brain injury
Associations of Collegiate Football Career and Incident Concussion with Players’ Health: A Longitudinal Study from the CARE Consortium

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Background and Rationale In recent years, the growing concern surrounding sports-related concussions has prompted educators, …

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Functional neurological disorders
Autoimmune psychosis: Psychopathological patterns and outcome after immunotherapy

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Autoimmune Psychosis Overview Autoimmune psychosis is an emerging area of interest in neurology and psychiatry, …

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Headaches
Efficacy, safety, and tolerability of chenodeoxycholic acid (CDCA) in adult patients with cerebrotendinous xanthomatosis (RESTORE): a randomized withdrawal, double-blind, placebo-controlled, crossover phase 3 study

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Efficacy of Chenodeoxycholic Acid Chenodeoxycholic acid (CDCA) has emerged as a critical therapeutic option for …

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Functional neurological disorders
Neuroimaging Biomarkers of Post-acute Sequelae of Covid (PASC)

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Neuroimaging Techniques and PASC Neuroimaging techniques have emerged as powerful tools in understanding the neurological …

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Functional neurological disorders
Silencer variants are key drivers of gene upregulation in Alzheimer’s disease

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Silencer Variants and Gene Regulation Recent advancements in genetic research have shed light on the …

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Functional neurological disorders
Regulation of chronic neuroinflammation through dietary herbal products

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Role of Dietary Herbal Products in Neuroinflammation Dietary herbal products have garnered significant interest in …

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Traumatic brain injury
Retinal manifestations of traumatic brain injury

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Retinal Changes Associated with Traumatic Brain Injury Traumatic brain injury (TBI) can lead to various …

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Functional neurological disorders
Electroencephalographic aspects and phenotypic characteristics in children with autism

by myneuronews April 28, 2025

by myneuronews April 28, 2025

Electroencephalographic Findings in Autism Electroencephalography (EEG) has become an essential tool in understanding the neurological …

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Dementia
Resistance and resilience to Alzheimer’s disease in Down syndrome

by myneuronews April 28, 2025

by myneuronews April 28, 2025

Understanding Alzheimer’s Disease in Down Syndrome Alzheimer’s disease (AD) is a multifaceted neurodegenerative condition characterized …

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Functional neurological disorders
Milestone Review: Unlocking the Proteomics of Glycine Receptor Complexes

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Proteomic Analysis of Glycine Receptors The detailed examination of glycine receptors (GlyRs) through proteomic analysis …

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Current trends and projections for potential acupuncture needs globally and in China: evidence from the Global Burden of Disease Study 2021
Global Acupuncture Needs Assessment The assessment of global acupuncture needs involves a multi-faceted approach that…
Plasma extracellular vesicles and phosphorylated tau 181 as early biomarkers of cognitive impairment in Alzheimer’s dementia
Study Overview The focus of this research is on exploring the potential of plasma extracellular…
Development and Evaluation of Upper Extremity Movement Quality Outcome Measures for Individuals with Functional Movement Disorder
Methodology for Movement Quality Assessment The study employed a comprehensive methodology for assessing upper extremity…
The Clinical Utility of a Novel Multimodal Assessment Battery for Acute Sport-Related Concussion
Assessment Framework The evaluation of acute sport-related concussions necessitates a multidimensional approach that integrates various…
Associations of Symptomatic Head Trauma/Concussion Diagnosis with Sleep-Related Outcomes in Children
Study Background The relationship between head trauma and its subsequent effects on children’s sleep patterns…

Management of the paediatric patient with acute head trauma
Acute head trauma (AHT) leading to traumatic brain injury is an important cause of paediatric morbidity and mortality. Injury severity depends on the mechanism of trauma and age of the child. The vast majority of childhood AHT cases are mild, require no therapy, and leave no long-term sequelae. However, it is important to identify individuals […]
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
CONCLUSION: Post-concussion sex differences in creatine concentrations were detected, as higher creatine levels moderately correlated with patient-reported outcomes. Creatine may reflect altered energy dynamics in the brain. The absence of a non-injured control group limits determination of whether these differences are concussion-specific or reflective of baseline physiology.
Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
Chronic neuroinflammation is recognized as a pivotal mechanism responsible for secondary damage following mild traumatic brain injury (mTBI), underscoring the critical need for therapeutic strategies capable of mitigating this pathological process. This study evaluated the anti-inflammatory properties of stearidonic acid ethanolamide (SDEA, C20H33NO2). The findings indicate that mTBI triggers persistent neuroinflammation, which is correlated with […]
Appropriateness of imaging requests for pediatric traumatic brain injury in the emergency department: a retrospective cross-sectional study
CONCLUSION: A significant gap exists between clinical practice and guideline-based imaging for pediatric TBI in Chile. Reinforcing validated decision tools may help optimize imaging use and minimize unnecessary radiation exposure.
Preexisting Mental Health Disorders Are Associated With Acute Clinical Presentation and Longitudinal Recovery Trajectories in Adolescents With Concussion
This secondary analysis examined the association between preexisting mental health conditions and clinical recovery trajectories in adolescents with concussion. Adolescents (13-17; n = 1238) completed clinical assessments (Post-Concussion Symptom Inventory [PCSI] ≤48 hours postinjury; PCSI/ Pediatric Quality of Life [PedsQL] for 3 months) and were categorized into control, anxiety, depression, or combined anxiety/depression groups. Acute […]