Role of sirtuin 2 in the brain is cell-type and context-dependent: Implications for therapeutic targeting
Role of Sirtuin 2 in Neuronal Function Sirtuin 2 (SIRT2) is a member of the sirtuin family of proteins, which […]
ALDH2 deficiency exacerbates acrolein-mediated neuropathology in multiple sclerosis
Study Overview This research explores the role of ALDH2 deficiency in the context of multiple sclerosis (MS) and its interaction
ALDH2 deficiency exacerbates acrolein-mediated neuropathology in multiple sclerosis Read Post »
Challenges and Innovation for Diagnosing and Treatment of Secondary Progressive Multiple Sclerosis
Challenges in Diagnosis Diagnosing secondary progressive multiple sclerosis (SPMS) presents a multitude of challenges, primarily due to the complex and
FreeSurfer-Based MRI Volumetry Reveals Thalamic and Hippocampal Atrophy as Significant Correlates of Disability in Multiple Sclerosis
Study Overview The research aimed to delve into the relationship between brain structure and the level of disability in individuals
Systemic implications of osteoarthritis: from local degeneration to systemic metabolic Dysregulation
Systemic Effects of Osteoarthritis Osteoarthritis, traditionally perceived as a localized joint disorder, has increasingly been recognized for its broader systemic
Growth hormone deficiency following traumatic brain injury in adults: Still much of a clinical enigma
Growth Hormone Role in Brain Injury Growth hormone (GH) plays a critical role in various physiological processes, including growth, metabolism,
Functional Neurologic Disorder: A Practical Guide for Individuals and Families
Understanding Functional Neurologic Disorder Functional Neurologic Disorder (FND) represents a complex interplay between the mind and body, leading to a
Functional Neurologic Disorder: A Practical Guide for Individuals and Families Read Post »
Myelin antigen-specific effector CD8+ T cells induce chronic CNS autoimmunity in a CD4+ T cell-dependent manner
Study Overview The investigation aimed to elucidate the mechanisms by which myelin antigen-specific effector CD8+ T cells contribute to the
Signaling pathways driving multiple sclerosis: From mechanisms to natural‑product interventions
Signaling Pathways in Multiple Sclerosis Multiple sclerosis (MS) is a complex autoimmune disease characterized by the immune system’s attack on
Radiofrequency and pulsed magnetic fields attenuate LPS-induced neuroinflammation and demyelination via PI3K/AKT/HIF-1alpha-mediated neurovascular protection
Therapeutic Mechanisms of Radiofrequency and Pulsed Fields The therapeutic mechanisms underlying the effects of radiofrequency (RF) and pulsed magnetic fields