Tag:

biomarkers

Dementia
Concurrent detection of cognitive impairment and amyloid positivity with a multimodal machine learning-enabled digital cognitive assessment

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Cognitive Impairment Detection Cognitive impairment represents a spectrum of conditions that affect an individual’s cognitive …

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Headaches
Vestibular migraine vs. migraine only: integrated transcriptome-clinical profiling reveals shared inflammation and divergent metabolic pathways for targeted therapy

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Study Overview This research investigates the similarities and differences between vestibular migraine and typical migraine …

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Traumatic brain injury
Glymphatic Dysfunction Reflects Post-Concussion Symptoms: Changes Within 1 Month and After 3 Months

by myneuronews December 10, 2025

by myneuronews December 10, 2025

Study Overview The research explores the relationship between glymphatic dysfunction and post-concussion symptoms over a …

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Traumatic brain injury
Plasma and Imaging Biomarker Changes Following Rotational and Contusional Models of Traumatic Brain Injury in Adolescent Pigs

by myneuronews December 10, 2025

by myneuronews December 10, 2025

Study Overview This research investigates the biochemical and imaging alterations resulting from two distinct forms …

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Dementia
Increased Blood Levels of NfL, GFAP, and Placental Growth Factor After Radiotherapy to the Brain

by myneuronews December 9, 2025

by myneuronews December 9, 2025

Study Overview The study investigated the changes in specific biomarkers in the blood of patients …

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Traumatic brain injury
From injury to inference: Neuropsychological reasoning across divergent mild traumatic brain injury (mTBI) criteria

by myneuronews December 8, 2025

by myneuronews December 8, 2025

Neuropsychological Framework The complex interplay between brain function and behavior necessitates a robust neuropsychological framework, …

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Dementia
Differential microglial responses to structurally distinct alpha-synuclein polymorphs

by myneuronews December 6, 2025

by myneuronews December 6, 2025

Differential Responses of Microglia Microglia, the resident immune cells of the central nervous system, exhibit …

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Traumatic brain injury
Neurobehavioral disorders: efficacy of post-hospital specialty programs

by myneuronews December 5, 2025

by myneuronews December 5, 2025

Program Outcomes The effectiveness of post-hospital specialty programs aimed at treating neurobehavioral disorders is evaluated …

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Traumatic brain injury
Development of a modified weight-drop apparatus for closed-skull, repetitive mild traumatic brain injuries in a mouse model

by myneuronews December 4, 2025

by myneuronews December 4, 2025

Study Overview This research focuses on creating a refined apparatus designed to induce mild traumatic …

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Traumatic brain injury
Mechanisms of naozhenning in inhibiting neuronal ferroptosis and alleviating brain recurrent mild traumatic brain injury in a rat model

by myneuronews December 4, 2025

by myneuronews December 4, 2025

Mechanisms of Ferroptosis Inhibition Ferroptosis is a distinct form of regulated cell death characterized by …

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Admission blood glucose and neutrophil-to-lymphocyte ratio for differentiating CT-positive from CT-negative mild traumatic brain injury
This study aimed to assess the diagnostic utility of routine laboratory biomarkers in adults with mTBI. We conducted a prospective study of patients who were admitted to the neurosurgical department with mTBI, had admission laboratory data available, and a brain CT scan was performed. The cohort included 101 patients (mean age: 59 ± 23.14 years). […]
Bidirectional Relationship Between Mental Health and Sports Injury in Adolescents: A Systematic Review and Meta-analysis
CONCLUSIONS: We found evidence for a bidirectional relationship between sports injuries and mental health in adolescent athletes. Further research is needed to elucidate the mechanisms underlying this relationship. Early interventions focusing on supporting mental health after sports injury, and addressing pre-existing mental health issues to reduce the risk of subsequent injury, should be tailored towards […]
Does Timing of Concussion in Season Affect Incidence and Recovery in Division I Collegiate Football Players? A CARE Consortium Study
CONCLUSIONS: In a multi-institution cohort of collegiate football players, preseason resulted in the highest incidence of concussions, while early and late-season concussions had significantly longer time to SR compared to preseason. These temporal patterns suggest that contextual factors may influence concussion outcomes and warrant mechanistic investigation to inform future management strategies.
Ultra-high contrast MRI of the brain and spinal cord using directly acquired and synthetic BipoLAr Inversion Recovery (BLAIR) images
Ultra-high contrast (UHC) magnetic resonance imaging (MRI) is a term used to describe magnetic resonance (MR) imaging that shows abnormalities with high contrast when little or no abnormality is seen on common conventional state-of-the-art MR images. It is achieved without the use of increased static or gradient magnetic fields. UHC can be accomplished by using […]
Functional Magnetic Resonance Imaging (fMRI) and Music Therapy for Concussion: A Case Report
Effective treatments for mild traumatic brain injury (mTBI) are limited and are insufficient to address patient symptoms and recovery. We report a case of an mTBI patient with debilitating visual symptoms who experienced profound symptom relief and increased functional capacity after music therapy (MT) (passive listening to specific music pieces). After other mTBI patients reported […]