Background and Rationale The increasing prevalence of Attention-Deficit/Hyperactivity Disorder (ADHD) among adolescents has led to …
biomarkers
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Traumatic brain injury
The kynurenine pathway in pediatric “mild-to-moderate” traumatic brain injury: translational insights from a prospective human study and a large-animal model
by myneuronewsby myneuronewsKynurenine Pathway Mechanisms The kynurenine pathway is a critical metabolic route for the amino acid …
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Traumatic brain injury
Brain Ischemia Across Injury Severity in Traumatic Brain Injury and an Association with Abusive Head Trauma
by myneuronewsby myneuronewsPathophysiology of Brain Ischemia Brain ischemia occurs when there is a deficiency of blood supply …
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Dementia
The CSF Levels of Mitochondrial Phosphoenolpyruvate Carboxykinase 2 as a Novel Biomarker in Alzheimer’s Disease
by myneuronewsby myneuronewsStudy Overview The research focuses on the role of mitochondrial phosphoenolpyruvate carboxykinase 2 (PEPCK-M) levels …
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Traumatic brain injury
2Innate immune signaling mediates differential acute and long-term outcomes of repeated vs. single TBI in Drosophila
by myneuronewsby myneuronewsStudy Overview The investigation centers around understanding how innate immune signaling influences the outcomes of …
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Dementia
In an older-age vascular cohort, carotid stenosis is associated with processing speed and executive function cognitive deficits, which correlate with p-tau217
by myneuronewsby myneuronewsStudy Overview The research focused on understanding the relationship between carotid stenosis and cognitive deficits …
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Traumatic brain injury
Biomarkers for prediction of chronic traumatic encephalopathy-like pathology following repeated mild traumatic brain injury in rats are partially sex- and age-dependent
by myneuronewsby myneuronewsStudy Overview The research embarked on an investigation into the long-term effects of repeated mild …
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Dementia
Loss of C9orf72 impacts the peripheral neuromuscular system via immune dysregulation and accelerates the progression of amyotrophic lateral sclerosis in SOD-1 mutant mice
by myneuronewsby myneuronewsImpact of C9orf72 Loss on Neuromuscular Systems The loss of the C9orf72 gene has been …
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Dementia
Dynamic functional connectivity and transcriptomic signatures reveal stage-dependent brain network dysfunction in Alzheimer’s disease spectrum
by myneuronewsby myneuronewsStudy Overview The research focused on understanding the intricate relationship between brain network connectivity and …
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Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity
by myneuronewsby myneuronewsBiomarkers in cerebrospinal fluid analysis Cerebrospinal fluid (CSF) serves as a crucial medium for assessing …
