Tag:

blood-brain barrier

Dementia
Loss of C9orf72 impacts the peripheral neuromuscular system via immune dysregulation and accelerates the progression of amyotrophic lateral sclerosis in SOD-1 mutant mice

by myneuronews November 15, 2025

by myneuronews November 15, 2025

Impact of C9orf72 Loss on Neuromuscular Systems The loss of the C9orf72 gene has been …

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Traumatic brain injury
AQP4 in cerebrospinal fluid correlates with severity and prognosis in moderate to severe traumatic brain injury

by myneuronews October 25, 2025

by myneuronews October 25, 2025

Background and Rationale Traumatic brain injury (TBI) is a significant public health concern, often resulting …

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Traumatic brain injury
Associations between traumatic brain injury and the prevalence of Alzheimer’s disease dementia and behavioral and psychological symptoms of dementia: A retrospective cohort study

by myneuronews August 29, 2025

by myneuronews August 29, 2025

Associations between TBI and Alzheimer’s Disease Traumatic brain injury (TBI) has garnered significant interest as …

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Traumatic brain injury
Chronic traumatic encephalopathy

by myneuronews August 29, 2025

by myneuronews August 29, 2025

Pathophysiology of Chronic Traumatic Encephalopathy Chronic traumatic encephalopathy (CTE) is a neurodegenerative condition associated with …

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Traumatic brain injury
Triamcinolone-loaded nanocarriers: a novel strategy to mitigate cognitive and emotional sequelae induced by traumatic brain injury via modulation of oxidative stress

by myneuronews August 28, 2025

by myneuronews August 28, 2025

Study Overview This research investigates the innovative use of triamcinolone-loaded nanocarriers as a strategy to …

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Dementia
High-affinity transferrin receptor binding improves brain delivery of bispecific antibodies at tracer dose

by myneuronews August 22, 2025

by myneuronews August 22, 2025

Study Overview The research focused on improving the delivery of bispecific antibodies to the brain. …

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Dementia
Vascular Contributions to Cognitive Impairment and Dementia in the United States: Prevalence and Incidence: A Scientific Statement From the American Heart Association

by myneuronews August 18, 2025

by myneuronews August 18, 2025

Vascular Contributions to Cognitive Health The relationship between vascular health and cognitive function is a …

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Headaches
Cerebral Amyloid Angiopathy-Related Inflammation: Clinical Characteristics and Treatment Experience

by myneuronews August 12, 2025

by myneuronews August 12, 2025

Clinical Characteristics Cerebral Amyloid Angiopathy-Related Inflammation (CAA-RI) manifests through a variety of clinical symptoms that …

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Functional neurological disorders
Double-edged sword effect of Sutterella in neurological disorders: implications for the gut-brain axis and neuroimmune interactions

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Sutterella and its Role in Neurological Disorders Sutterella, a genus of bacteria predominantly found in …

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Functional neurological disorders
Luminal Vascular Dysfunction Drives Rapid Blood Brain Barrier Injury in Hyperglycemic Stroke: Key Roles for Luminal Glycocalyx and Complement

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Luminal Glycocalyx and Its Role in Blood Brain Barrier Integrity The luminal glycocalyx is a …

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Efficacy and safety of relugolix therapy for symptomatic uterine fibroids: a systematic review and meta-analysis
Efficacy of Relugolix Relugolix, an oral gonadotropin-releasing hormone (GnRH) antagonist, has demonstrated notable efficacy in…
Disclosure of onset-predictive biomarker results to research participants at risk of genetic frontotemporal dementia: a European perspective
Background on Genetic Frontotemporal Dementia Genetic frontotemporal dementia (FTD) is a group of neurodegenerative disorders…
DCPat-XFE: an explainable EEG model for psychogenic nonepileptic seizure detection
Study Summary The study presents the DCPat-XFE model, designed to enhance the detection of psychogenic…
Prevalence of Vestibular Disorders in Moderate-Severe Traumatic Brain Injury (TBI): A Scoping Review
Study Overview The focus of this scoping review is to explore the prevalence of vestibular…
Association of sports and physical activity with mild traumatic brain injury and behavioral and neurocognitive function
Study Overview The article investigates the relationship between engagement in sports and physical activities and…

Prevalence of Vestibular Disorders in Moderate-Severe Traumatic Brain Injury (TBI): A Scoping Review
CONCLUSION: Vestibular dysfunction is prevalent among individuals with moderate-to-severe TBI, although the methods of assessment vary. Future studies should aim to be more consistent in documenting the severity of TBI, the evaluation of vestibular dysfunction, and determining interventions that are most beneficial for this population.
Association of sports and physical activity with mild traumatic brain injury and behavioral and neurocognitive function
CONCLUSION: Participation in soccer and/or climbing showed positive associations with mTBI, while participation in yoga showed a negative association. Sports/PA participation was related to better behavioral/emotional and neurocognitive functioning, regardless of children's injury history.
Educational Perspectives on Compassionate Concussion Care: A Scoping Review
CONCLUSION: This review highlights the implicit paradigms shaping concussion-care education and their limitations for cultivating compassion. Constructivism offers the most promise for advancing compassionate practice by fostering collaboration, reflection, and learner agency. Given the interpersonal, cognitive and contextual demands of concussion care, adopting a constructivist orientation may better prepare physicians to meet patient and caregiver […]
A challenge to improve the Quality of Care.Rehabilitation outcome measures in the Emergency Department: a scoping review
CONCLUSIONS: The use of validated outcome measures by physiotherapists in EDs is feasible and clinically valuable; however, a lack of standardization and limited high-quality evidence particularly within the Italian healthcare context highlight the need for further research to establish shared outcome sets and transferable models of care.
Gaps in Access to Cognitive Rehabilitation Referrals Among Veterans with Mild Traumatic Brain Injury
CONCLUSIONS: These results suggest that while cognitive rehabilitation services tend to be allocated to those in need, significant gaps in access exist. Findings lay the foundation for developing strategies that expand access to beneficial cognitive rehabilitation among Veterans with mTBI, reducing their cognitive symptoms and enhancing their daily function.