Tag:

blood-brain barrier

Traumatic brain injury
Associations between traumatic brain injury and the prevalence of Alzheimer’s disease dementia and behavioral and psychological symptoms of dementia: A retrospective cohort study

by myneuronews August 29, 2025

by myneuronews August 29, 2025

Associations between TBI and Alzheimer’s Disease Traumatic brain injury (TBI) has garnered significant interest as …

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Traumatic brain injury
Chronic traumatic encephalopathy

by myneuronews August 29, 2025

by myneuronews August 29, 2025

Pathophysiology of Chronic Traumatic Encephalopathy Chronic traumatic encephalopathy (CTE) is a neurodegenerative condition associated with …

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Traumatic brain injury
Triamcinolone-loaded nanocarriers: a novel strategy to mitigate cognitive and emotional sequelae induced by traumatic brain injury via modulation of oxidative stress

by myneuronews August 28, 2025

by myneuronews August 28, 2025

Study Overview This research investigates the innovative use of triamcinolone-loaded nanocarriers as a strategy to …

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Dementia
High-affinity transferrin receptor binding improves brain delivery of bispecific antibodies at tracer dose

by myneuronews August 22, 2025

by myneuronews August 22, 2025

Study Overview The research focused on improving the delivery of bispecific antibodies to the brain. …

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Dementia
Vascular Contributions to Cognitive Impairment and Dementia in the United States: Prevalence and Incidence: A Scientific Statement From the American Heart Association

by myneuronews August 18, 2025

by myneuronews August 18, 2025

Vascular Contributions to Cognitive Health The relationship between vascular health and cognitive function is a …

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Headaches
Cerebral Amyloid Angiopathy-Related Inflammation: Clinical Characteristics and Treatment Experience

by myneuronews August 12, 2025

by myneuronews August 12, 2025

Clinical Characteristics Cerebral Amyloid Angiopathy-Related Inflammation (CAA-RI) manifests through a variety of clinical symptoms that …

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Functional neurological disorders
Double-edged sword effect of Sutterella in neurological disorders: implications for the gut-brain axis and neuroimmune interactions

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Sutterella and its Role in Neurological Disorders Sutterella, a genus of bacteria predominantly found in …

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Functional neurological disorders
Luminal Vascular Dysfunction Drives Rapid Blood Brain Barrier Injury in Hyperglycemic Stroke: Key Roles for Luminal Glycocalyx and Complement

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Luminal Glycocalyx and Its Role in Blood Brain Barrier Integrity The luminal glycocalyx is a …

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Functional neurological disorders
Luminal Vascular Dysfunction Drives Rapid Blood Brain Barrier Injury in Hyperglycemic Stroke: Key Roles for Luminal Glycocalyx and Complement

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Luminal Vascular Dysfunction as a Mechanism In examining how luminal vascular dysfunction contributes to blood-brain …

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Functional neurological disorders
Role of ALOX5AP in the pathogenesis of cerebral small vessel disease: impact of inflammation and lipid metabolism dysregulation

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Pathophysiological Mechanisms of ALOX5AP The role of ALOX5AP (Arachidonate 5-Lipoxygenase Activating Protein) in the pathogenesis …

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State-of-the-art preclinical techniques to study the impact of spreading depolarizations in awake rodents
Overview of Spreading Depolarizations Spreading depolarizations (SDs) refer to a wave of electrical activity that…
Wealth, income and dementia in Germany: longitudinal findings from a representative survey among the oldest old
Wealth and Income Disparities In Germany, wealth and income disparities significantly affect the elderly population,…
Unraveling functional neurological disorder in pediatric populations: A systematic review of diagnosis, treatment, and outcomes
Understanding Functional Neurological Disorder in Pediatrics Functional neurological disorder (FND) presents a complex challenge in…
Diagnostic screening for epilepsy, functional neurological disorder, and other paroxysmal disorders: A clinical survey study
Clinical Significance of Diagnostic Screening Diagnostic screening plays a critical role in the timely identification…
A pilot study evaluating early psychosocial risk and brain health outcomes in Veterans with mild TBI
Background and Rationale Traumatic brain injury (TBI), particularly mild forms, poses significant concerns for the…

The role of mouthguards in the prevention of oro-facial trauma
The role of a sports mouthguard has been well established as one of protecting teeth from trauma particularly during contact sports. The aim of this study is to review the roles of sports mouthguard at both an elite and recreational level. From the history of the first mouthguards, to a modern custom-made mouthguard, the role […]
A pilot study evaluating early psychosocial risk and brain health outcomes in Veterans with mild TBI
The goal of this pilot study was to describe the relationship between early psychosocial risk (i.e., adverse childhood experiences, neighborhood disadvantage, multiple relocations) and brain health outcomes among Veterans with mild TBI. Veterans (N = 76) with mild TBI participated at an outpatient VA. This cross-sectional study involved the collection and analysis of retrospective self-report […]
Chronic traumatic encephalopathy
Chronic traumatic encephalopathy (CTE) is a neurodegenerative disease caused by repetitive head impacts from contact sports, physical violence, and other causes. The urgency of the problem is due to the high incidence of pathology, not only in adults, but, most importantly, in the pediatric population. The paper presents a review of the literature in databases […]
Self-reported head trauma among Native Americans who inject methamphetamine: a cross-sectional study
INTRODUCTION: Traumatic brain injury (TBI) is a significant public health concern, with disparities in prevalence and care access among Native Americans. The syndemic relationship between substance use and TBI remains underexplored in Native Americans who inject methamphetamine, a population at high risk for both conditions. This study examines the association between self-reported TBI and substance […]
From Head to Toe: Investigating Postconcussion Risks for Lower Extremity Injuries in Young Athletes
CONCLUSION: This study found a significant increase in several lower extremity injuries ≤1 year after a concussion. Additional studies are warranted to better understand the different factors affecting concussion risk, which could include inadequate return-to-sport (RTS) protocols and prolonged vestibular dysfunction.