Tag:

blood-brain barrier

Functional neurological disorders
Double-edged sword effect of Sutterella in neurological disorders: implications for the gut-brain axis and neuroimmune interactions

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Sutterella and its Role in Neurological Disorders Sutterella, a genus of bacteria predominantly found in …

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Functional neurological disorders
Luminal Vascular Dysfunction Drives Rapid Blood Brain Barrier Injury in Hyperglycemic Stroke: Key Roles for Luminal Glycocalyx and Complement

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Luminal Glycocalyx and Its Role in Blood Brain Barrier Integrity The luminal glycocalyx is a …

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Functional neurological disorders
Luminal Vascular Dysfunction Drives Rapid Blood Brain Barrier Injury in Hyperglycemic Stroke: Key Roles for Luminal Glycocalyx and Complement

by myneuronews July 16, 2025

by myneuronews July 16, 2025

Luminal Vascular Dysfunction as a Mechanism In examining how luminal vascular dysfunction contributes to blood-brain …

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Functional neurological disorders
Role of ALOX5AP in the pathogenesis of cerebral small vessel disease: impact of inflammation and lipid metabolism dysregulation

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Pathophysiological Mechanisms of ALOX5AP The role of ALOX5AP (Arachidonate 5-Lipoxygenase Activating Protein) in the pathogenesis …

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Functional neurological disorders
Role of ALOX5AP in the pathogenesis of cerebral small vessel disease: impact of inflammation and lipid metabolism dysregulation

by myneuronews July 12, 2025

by myneuronews July 12, 2025

Pathophysiological Mechanisms of ALOX5AP ALOX5AP (Arachidonate 5-Lipoxygenase-Activating Protein) plays a pivotal role in the pathophysiology …

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Functional neurological disorders
Wogonin Inhibits Oxidative Stress in Hypoxia-Induced hCMEC/D3 Cells Through Suppressing CXCL8-Mediated TLR4/NF-κB Pathway

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Mechanisms of Wogonin in Oxidative Stress Wogonin, a naturally occurring flavonoid found in various plants, …

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Headaches
The efficacy and safety of intrathecal pemetrexed for leptomeningeal metastasis from non-small cell lung cancer: a single-arm meta-analysis of Chinese patients

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview This study focuses on evaluating the effectiveness and safety of intrathecal pemetrexed in …

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Traumatic brain injury
Plasma levels of biomarkers associated with vasodilation and neuroinflammation in pediatric patients with head trauma and their relationship with clinical characteristics of patients

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Biomarkers of Vasodilation and Neuroinflammation In recent studies focusing on pediatric patients with head trauma, …

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Traumatic brain injury
Neurobiomarkers for Traumatic Brain Injury: Comparison of Serum Values Within 24 Hours of Injury With Glasgow Coma Scale (GCS) Scores in a Prospective Cohort Trial

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Neurobiomarkers in Traumatic Brain Injury Neurobiomarkers represent measurable indicators located in the body, which provide …

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Traumatic brain injury
Microstructural Damage Progression in the Pia-Arachnoid Complex

by myneuronews June 29, 2025

by myneuronews June 29, 2025

Microstructural Changes Observed The study of microstructural changes within the pia-arachnoid complex reveals a complex …

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Construct Validity of the Tower of London Test: Generating a Construct Specification Equation Relating Problem Characteristics to Problem Difficulty in a Sample of Veterans with Mild Traumatic Brain Injury
The Tower of London (TOL) is a set of problem-solving tasks that are commonly used to measure cognition. No studies have developed construct specification equations (CSEs) to mathematically quantify how the characteristics of test problems relate to the difficulty of the problem in the TOL. We aimed to investigate the relationship between TOL problem characteristics […]
Functional hearing difficulties in Veterans with blast and blunt head trauma are associated with reduced fractional anisotropy in putative auditory radiations
OBJECTIVES: Veterans of recent military conflicts have experienced a high rate of mild traumatic brain injury (mTBI) due to blast exposure. A debilitating symptom often reported by such patients is an impaired ability to perceive complex sounds (e.g., impaired speech comprehension in noisy environments). In a prior report, we found a continuous measure of historical […]
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury
Traumatic brain injury (TBI) is a serious clinical and social problem. Millions of TBI cases, that require hospitalization and consequently burden social security systems, are reported each year. Analysis of the time course of changes that occur in the brain after primary injury may help indicate therapeutic goals and treatment directions that will minimize severe […]
Clinical outcomes and quality of life after endovascular embolization for vein of Galen aneurysmal malformation (VGAM): a study from a low-and middle-income country
CONCLUSION: The long-term neurological outcomes of VGAM embolization remain variable. While staged embolization was significantly associated with outcomes, other factors may contribute. Larger studies are needed to determine the optimal approach for embolization to improve outcomes.
A Proof-of-Concept Development on Speech Analysis for Concussion Detection
Speech signal analysis to support objective clinical decision-making has gained immense interest, especially in neurological disorders. This research assessed the feasibility of speech analysis on the detection of concussions. Using a speech dataset from 82 concussed and 82 healthy participants, we extracted two speech feature sets focusing on Mel Frequency Cepstral Coefficients (MFCCs) to characterize […]