Tag:

blood-brain barrier

Traumatic brain injury
Genome-wide analysis of lncRNA m6A methylation in the mouse cortex after repetitive mild traumatic brain injury

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Background on lncRNA and m6A Methylation Long non-coding RNAs (lncRNAs) are an intriguing class of …

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Functional neurological disorders
Changes in brain functional connectivity and clinical correlations in neuromyelitis optica spectrum disorder: a longitudinal resting-state fMRI study

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Overview of Neuromyelitis Optica Spectrum Disorder Neuromyelitis Optica Spectrum Disorder (NMOSD) is a rare, autoimmune …

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Traumatic brain injury
Imaging a concussion and the ensuing immune response at the blood-brain barrier

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Understanding the Blood-Brain Barrier The blood-brain barrier (BBB) is a highly selective permeability barrier that …

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Functional neurological disorders
S100B Mitigates Cytoskeletal and Mitochondrial Alterations in a Glial Cell Model of Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Pathophysiology of Autosomal Recessive Spastic Ataxia Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS) is characterized …

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Headaches
Neurological complications of orthopoxvirus infections: neurotropism and neurovirulence

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Neurological Manifestations in Orthopoxvirus Infection Orthopoxvirus infections are associated with a variety of neurological manifestations …

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Dementia
Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer’s Disease

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Treatment Strategy Overview In recent years, the exploration of innovative approaches to treat Alzheimer’s disease …

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Traumatic brain injury
Dietary supplementation roles in concussion management: A systematic review

by myneuronews May 5, 2025

by myneuronews May 5, 2025

Supplementation Strategies in Concussion Care Various nutritional strategies have been proposed as adjuncts to traditional …

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Traumatic brain injury
Hybrid membrane-coated Cyclosporine A nanocrystals preventing secondary brain injury via alleviating neuroinflammatory and oxidative stress

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Therapeutic Approach The therapeutic strategy explored in this study focuses on utilizing hybrid membrane-coated nanocrystals …

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Medical professionals Post traumatic epilepsy Traumatic brain injury
Understanding the Pathophysiology of Post-Traumatic Epilepsy

by Ioannis Mavroudis February 14, 2024

by Ioannis Mavroudis February 14, 2024

Astrocytes, traditionally viewed as mere support cells, play a pivotal role in the development of …

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Current trends and projections for potential acupuncture needs globally and in China: evidence from the Global Burden of Disease Study 2021
Global Acupuncture Needs Assessment The assessment of global acupuncture needs involves a multi-faceted approach that…
Plasma extracellular vesicles and phosphorylated tau 181 as early biomarkers of cognitive impairment in Alzheimer’s dementia
Study Overview The focus of this research is on exploring the potential of plasma extracellular…
Development and Evaluation of Upper Extremity Movement Quality Outcome Measures for Individuals with Functional Movement Disorder
Methodology for Movement Quality Assessment The study employed a comprehensive methodology for assessing upper extremity…
The Clinical Utility of a Novel Multimodal Assessment Battery for Acute Sport-Related Concussion
Assessment Framework The evaluation of acute sport-related concussions necessitates a multidimensional approach that integrates various…
Associations of Symptomatic Head Trauma/Concussion Diagnosis with Sleep-Related Outcomes in Children
Study Background The relationship between head trauma and its subsequent effects on children’s sleep patterns…

Neuroimaging correlates of symptom burden and functional recovery following mild traumatic brain injury: A systematic review
CONCLUSIONS: Acute MRI, when contextualised with clinical data, helps delineate correlates of mTBI symptom burden and functional recovery. To strengthen inference, future neuroimaging studies should prespecify and report symptom burden and functional recovery as core endpoints.
Structural brain alterations and predictors of clinical improvement in functional cognitive disorder after concussion
Functional cognitive disorder (FCD) is an under-studied yet likely prevalent subtype of functional neurological disorder (FND), with neural mechanisms that remain poorly understood. While studies of other FND subtypes have revealed structural and functional brain alterations across several large-scale brain networks, no study to date has investigated neural alterations in FCD. Here, we examined structural […]
Long-term health outcomes of adolescent mTBI: a scoping review
CONCLUSION: This review provides insight into the potential long-term concerns of adolescent mTBI and highlights areas needing further research for more robust conclusions. The review identifies critical considerations for health professionals when assessing adolescents with mTBI and creating recovery plans to promote full recovery with limited long-term impact.
Exploring sports-related concussion awareness and response amongst teenage grassroots soccer players in the UK: a qualitative study
CONCLUSIONS: Effective SRC management requires tailored education programs to overcome barriers and promote safety within grassroots youth soccer. Addressing gender norms and enhancing education can foster a culture of support and accountability, safeguarding the well-being of young athletes. There is a need for better awareness and more precautionary behaviors among all stakeholders in grassroots soccer.
Motion Sickness and Psychological and Vestibular Symptom Burden After Concussion
Given the potential interplay of psychological symptoms following pediatric concussion and vestibular dysfunction, we conducted a prospective cohort study of participants ages 8 to 19 ≤72 hours of injury from the emergency department to assess the association between motion sickness and outcomes. Participants completed visio-vestibular testing and symptom-based surveys at enrollment, with outcome assessment at […]