Tag:

brain function

Dementia
Enriched Environment Alleviate AD Pathological Progression by Reducing Microglia Complement Signaling in Aged Male APP/PS1 Mice

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Study Overview This research investigates the impact of enriched environments on Alzheimer’s disease (AD) progression …

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Functional neurological disorders
Therapeutic education for patients with functional neurological disorders

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Overview of Functional Neurological Disorders Functional Neurological Disorders (FND) are characterized by the presence of …

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Functional neurological disorders
Therapeutic education for patients with functional neurological disorders

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Understanding Functional Neurological Disorders Functional Neurological Disorders (FND) represent a group of conditions characterized by …

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Functional neurological disorders
Functional neurological disorders: history and current situation

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Current Understanding of Functional Neurological Disorders Functional Neurological Disorders (FND) represent a complex interplay between …

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Functional neurological disorders
Therapeutic education for patients with functional neurological disorders

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Therapeutic Approaches for FND Functional neurological disorders (FND) encompass a range of neurological symptoms that …

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Functional neurological disorders
Functional neurological disorders: history and current situation

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Historical Perspective on FND Functional neurological disorders (FND) have a rich and complex history that …

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Functional neurological disorders
Therapeutic education for patients with functional neurological disorders

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Understanding Functional Neurological Disorders Functional neurological disorders (FND) encompass a range of conditions where patients …

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Functional neurological disorders
Functional neurological disorders: history and current situation

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Overview of Functional Neurological Disorders Functional neurological disorders (FND) comprise a range of neurological symptoms …

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Functional neurological disorders
Mechanisms of motor dysfunction in functional neurological disorder: A narrative review

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Mechanisms of Motor Dysfunction Motor dysfunction in functional neurological disorder (FND) arises from a complex …

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Traumatic brain injury
The Role of MRI in Debunking the Fallacy of “Mild” Traumatic Brain Injury

by myneuronews September 5, 2025

by myneuronews September 5, 2025

The Importance of MRI in TBI Assessment Magnetic Resonance Imaging (MRI) plays a pivotal role …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]