Tag:

brain function

Functional neurological disorders
The adjunct role of pharmacotherapy in multimodal treatment of paediatric functional neurological disorder

by myneuronews August 1, 2025

by myneuronews August 1, 2025

Overview of Functional Neurological Disorder Functional Neurological Disorder (FND) represents a complex spectrum of symptoms …

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Functional neurological disorders
Spreading depolarisation (SD): a potential underlying mechanism in functional neurological disorder (FND)

by myneuronews August 1, 2025

by myneuronews August 1, 2025

Overview of Spreading Depolarisation Spreading depolarisation (SD) is a dynamic electrophysiological phenomenon characterized by a …

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Functional neurological disorders
Malignant catatonia in an adolescent with pogo transposable element derived with zinc finger domain (POGZ) gene mutation: case report

by myneuronews August 1, 2025

by myneuronews August 1, 2025

Case Presentation In this case, we present a 16-year-old adolescent who exhibited symptoms consistent with …

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Functional neurological disorders
Brain structural MRI marker for predicting conversion to Parkinson’s disease in individuals with prodromal symptoms

by myneuronews July 31, 2025

by myneuronews July 31, 2025

Brain Imaging Techniques Brain imaging plays a pivotal role in understanding neurological conditions, particularly in …

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Traumatic brain injury
Time-course responses following sports-related concussion:A multi-modality study

by myneuronews July 31, 2025

by myneuronews July 31, 2025

Study Overview The investigation into sports-related concussions addresses a significant and growing public health concern, …

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Functional neurological disorders
Investigating the role of a novel hemizygous FAAH2 variant in neurological and metabolic disorders

by myneuronews July 31, 2025

by myneuronews July 31, 2025

Role of FAAH2 in Neurological Disorders FAAH2, or fatty acid amide hydrolase 2, is an …

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Functional neurological disorders
Hyperuniform Networks of Active Magnetic Robotic Spinners

by myneuronews July 31, 2025

by myneuronews July 31, 2025

Network Characteristics of Magnetic Spinners The study of active magnetic robotic spinners offers fascinating insights …

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Functional neurological disorders
Post-Concussion Syndrome and Functional Neurological Disorder: Diagnostic Interfaces, Risk Mechanisms, and the Functional Overlay Model

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Clinical Features of Post-Concussion Syndrome Post-Concussion Syndrome (PCS) manifests through a variety of clinical features …

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Functional neurological disorders
Pyruvate Dehydrogenase Kinase 4 Underlies the Metabolic Disorder of Cardiomyocytes in Patients With Hypertrophic Cardiomyopathy From Hypertrophy to Heart Failure

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Metabolic Alterations in Cardiomyocytes In the realm of cardiology, understanding the changes that occur in …

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Functional neurological disorders
GSAformer: Group sparse attention transformer for functional brain network analysis

by myneuronews July 27, 2025

by myneuronews July 27, 2025

Methodology Overview The study introduced GSAformer, a novel model designed to improve the analysis of …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]