Tag:

brain function

Traumatic brain injury
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Clinical Phenotypes In chronic traumatic brain injury (TBI), individuals often manifest a variety of clinical …

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Functional neurological disorders
Fecal Microbiota Transplantation from Noni Fruit Phenolic-Rich Extract Intervention Mouse Donors Ameliorates Lipid Metabolism Disorder by Regulating the FXR-FGF15 Pathway in a Gut Microbiota-Dependent Manner

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Effects of Noni Fruit Extract on Gut Microbiota The study presented intriguing findings on how …

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Functional neurological disorders
Orbitofrontal Thickness and Network Associations as Transdiagnostic Signature of Amotivation Along the Bipolar-Schizophrenia Spectrum

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Transdiagnostic Framework In recent years, the understanding of mental health disorders has evolved to embrace …

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Functional neurological disorders
Lesion distribution and network mapping in dyskinetic cerebral palsy

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Lesion characteristics in dyskinetic cerebral palsy Dyskinetic cerebral palsy (CP) is a complex condition characterized …

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Traumatic brain injury
Application of Electroencephalography (EEG) in Combat Sports-Review of Findings, Perspectives, and Limitations

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Application of EEG in Combat Sports Electroencephalography (EEG) has emerged as a pivotal tool in …

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Traumatic brain injury
Assessment of White Matter Changes Using Quantitative T1rho Mapping in an Open-Field Low-Intensity Blast Mouse Model of Mild Traumatic Brain Injury (mTBI)

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Study Overview The study investigates the impact of mild traumatic brain injury (mTBI) on white …

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Functional neurological disorders
Correlation of Positive Signs of Functional Neurological Disorder With Headache Severity: A Prospective Cross-Sectional Study

by myneuronews June 26, 2025

by myneuronews June 26, 2025

Background on Functional Neurological Disorder Functional Neurological Disorder (FND) is a complex and often misunderstood …

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Functional neurological disorders
Managing functional neurological disorder: treatment recommendations for health professionals in Australia

by myneuronews June 24, 2025

by myneuronews June 24, 2025

Understanding Functional Neurological Disorder Functional Neurological Disorder (FND) presents a spectrum of neurological symptoms that …

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Functional neurological disorders
Investigating Resting-State Brain Activity in Adolescents with High-Functioning Autism Spectrum Disorder: Linking Fractional Amplitude of Low-Frequency Fluctuation to Clinical Symptoms

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Resting-State Brain Activity in Adolescents Resting-state brain activity refers to the spontaneous brain fluctuations that …

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Traumatic brain injury
Outcomes of recombinant growth hormone therapy in the traumatic brain injury population: A scoping review

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Study Overview The investigation focuses on the effects of recombinant growth hormone (rhGH) therapy in …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]