Tag:

brain function

Functional neurological disorders
Microglia-drive IRF8 upregulates complement pathway in Parkinson’s disease

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Microglia and Parkinson’s Disease Microglia, the resident immune cells of the brain, play a crucial …

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Functional neurological disorders
Perturbations in gut microbiota in autism spectrum disorder: a systematic review

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Gut Microbiota Alterations in Autism The gut microbiota consists of a diverse community of microorganisms …

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Functional neurological disorders
Microglia-drive IRF8 upregulates complement pathway in Parkinson’s disease

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Microglia and Parkinson’s Disease Pathophysiology Microglia, the resident immune cells of the central nervous system, …

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Functional neurological disorders
Loss of CD98HC phosphorylation by ATM impairs antiporter trafficking and drives glutamate toxicity in Ataxia telangiectasia

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Loss of CD98HC Phosphorylation and Its Effects The research highlights the critical role of CD98HC, …

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Functional neurological disorders
Microglia-drive IRF8 upregulates complement pathway in Parkinson’s disease

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Microglia and Parkinson’s Disease Microglia are the primary immune cells of the central nervous system, …

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Traumatic brain injury
Abstracts of the 5th Annual Meeting of the Canadian Concussion Network/Reseau Canadien des Commotions (CCN-RCC)

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Study Overview The 5th Annual Meeting of the Canadian Concussion Network (CCN-RCC) gathered researchers, healthcare …

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Traumatic brain injury
Sex-dependent blood-brain barrier alterations following repeated mild blast traumatic brain injury at varying inter-injury intervals

by myneuronews June 1, 2025

by myneuronews June 1, 2025

Study Overview The investigation focused on the impact of repeated mild blast traumatic brain injuries …

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Functional neurological disorders
A multicenter cross-sectional study to elucidate altered resting-state functional connectivity of the insular cortex in anorexia nervosa, segmented by functional localization

by myneuronews May 31, 2025

by myneuronews May 31, 2025

Functional Connectivity Assessment The assessment of functional connectivity in this study was intricately structured to …

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Stroke
Association of Life’s Crucial 9 with cognitive function and stroke risk: insights from the NHANES 2011-2014 study

by myneuronews May 31, 2025

by myneuronews May 31, 2025

Association of Life’s Crucial 9 and Cognitive Function Life’s Crucial 9 encompasses a set of …

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Functional neurological disorders
A 2025 update on treatment strategies for the Alzheimer’s disease spectrum

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Current Treatment Approaches The treatment landscape for Alzheimer’s disease has evolved considerably, reflecting a multifaceted …

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Aldehydic load as an objective imaging biomarker of mild traumatic brain injury
Mild traumatic brain injury (mTBI) is neurological impairment induced by biomechanical forces without structural brain damage, currently without an objective diagnostic tool. Downstream injury stems from oxidative damage leading to the production of neurotoxic aldehydes. A collagen-based 3D corticomimetic in vitro model of concussion was developed, confirming aldehyde production following impact. Total aldehyde levels were […]
Advancing next-generation brain organoid platforms for investigating traumatic brain injury from repeated blast exposures
Service members and law enforcement personnel are frequently exposed to blast overpressure during training and combat due to the use of heavy weaponry such as large-caliber rifles, explosives, and ordnance. The cumulative effects of these repeated low-level (
Plasma levels of biomarkers associated with vasodilation and neuroinflammation in pediatric patients with head trauma and their relationship with clinical characteristics of patients
CONCLUSION: Evaluation of pediatric patients with head trauma together with these neuropeptides may provide great benefits in deciding whether to perform radiography such as CT. However, due to the relatively low sensitivities in ROC analysis and small sample size, further studies are warranted before they may be used as a screening test to distinguish CT-positive […]
Trajectories of fear avoidance behavior and recovery after mild traumatic brain injury: Findings from the Toronto Concussion Study
CONCLUSION: Early fear avoidance behavior often decreases, but when it does not, it is associated with worse recovery from mTBI. These findings may inform the timing and design of interventions targeting fear avoidance behavior in patients with mTBI. (PsycInfo Database Record (c) 2025 APA, all rights reserved).
Proposed Reformulation of Brain Injury Criteria (BrIC) Using Head Rotation-Induced Brain Injury Thresholds Simulated and Derived Directly from A Subhuman Primate Finite Element Model
Recent studies have found that Brain Injury Criteria (BrIC) grossly overpredicts instances of real-world, severe traumatic brain injury (TBI). However, as it stands, BrIC is the leading candidate for a rotational head kinematics-based brain injury criteria for use in automotive regulation and general safety standards. This study attempts to understand why BrIC overpredicts the likelihood […]