Tag:

brain health

Dementia
The biomarker and clinical changes across the Alzheimer’s continuum study (BCAS): rationale, design, and baseline characteristics of the first 1,013 participants

by myneuronews December 23, 2025

by myneuronews December 23, 2025

Study Overview The BCAS study focuses on understanding the progression of Alzheimer’s disease through a …

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Traumatic brain injury
Neuronal and Glial Biomarkers in Urine of Athletes with Different Risks of Head Trauma to Monitor Sports-Related Concussions

by myneuronews December 19, 2025

by myneuronews December 19, 2025

Biomarkers in Sports-Related Concussions Sports-related concussions (SRC) represent a significant public health concern, particularly among …

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Traumatic brain injury
Neuronal and Glial Biomarkers in Urine of Athletes with Different Risks of Head Trauma to Monitor Sports-Related Concussions

by myneuronews December 19, 2025

by myneuronews December 19, 2025

Biomarkers in Urine The detection of biomarkers in urine has emerged as a promising method …

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Traumatic brain injury
Mechanisms of Concussions Among High-School Athletes in School-Sponsored Sports: Implications for Safety

by myneuronews December 19, 2025

by myneuronews December 19, 2025

Concussion Mechanisms in High-School Athletes The mechanisms underlying concussions among high-school athletes are multifaceted and …

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Traumatic brain injury
Ultra-high contrast MRI: a new technique for recognizing secondary changes to the brain in patients with persistent symptoms following traumatic brain injury

by myneuronews December 16, 2025

by myneuronews December 16, 2025

Ultra-high Contrast MRI Technique The development of ultra-high contrast magnetic resonance imaging (MRI) represents a …

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Traumatic brain injury
A comprehensive review on adaptive plasticity and recovery mechanisms post-acquired brain injury

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Adaptive Plasticity Mechanisms Adaptive plasticity refers to the brain’s ability to reorganize itself in response …

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Traumatic brain injury
A study on the association of apolipoprotein E with oxidative stress markers, neurological function, and cognitive impairment following traumatic brain injury

by myneuronews December 15, 2025

by myneuronews December 15, 2025

Association of Apolipoprotein E and Oxidative Stress Apolipoprotein E (ApoE) plays a crucial role in …

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Traumatic brain injury
Differential DNA Methylation of the Brain-Derived Neurotrophic Factor Gene is Observed after Pediatric Traumatic Brain Injury Compared with Orthopedic Injury

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Study Overview This study investigates the changes in DNA methylation of the brain-derived neurotrophic factor …

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Dementia
Concurrent detection of cognitive impairment and amyloid positivity with a multimodal machine learning-enabled digital cognitive assessment

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Cognitive Impairment Detection Cognitive impairment represents a spectrum of conditions that affect an individual’s cognitive …

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Traumatic brain injury
Traumatic Brain Injury Across the Lifespan and in Conflict Zones

by myneuronews December 11, 2025

by myneuronews December 11, 2025

Traumatic Brain Injury in Different Age Groups Traumatic brain injury (TBI) manifests distinctively across various …

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Macrophages and iNOS contribute to the effects of dural prolactin and repeated stress in mouse migraine models
Study Overview The investigation into the interplay between macrophages, inducible nitric oxide synthase (iNOS), and…
The biomarker and clinical changes across the Alzheimer’s continuum study (BCAS): rationale, design, and baseline characteristics of the first 1,013 participants
Study Overview The BCAS study focuses on understanding the progression of Alzheimer’s disease through a…
Women’s Issues and Female-specific Factors in Functional Neurological Disorder
Women’s Unique Experiences in FND Women facing Functional Neurological Disorder (FND) often encounter a unique…
Sex differences in the clinical characteristics of South African patients with functional seizures in a public and a private hospital
Sex Differences in Functional Seizures Research has increasingly highlighted the importance of sex differences in…
Developing Topics
Topic Identification In the early stages of research, selecting a compelling and relevant topic is…

Basic Science and Pathogenesis
CONCLUSION: Young amateur contact sports players are at risk for structural and microstructural brain injuries, including enlarged ventricles, cavum septum pellucidum, microvascular injury, blood-brain barrier breach, interface astrocytosis, and glymphatic remodeling. Future studies are needed to clarify the association between these early structural injuries after RHI and risk for CTE.
Interaction of Obese Body Mass Index and Comorbidities on Inflammatory Profiles and Clinical Outcomes After Traumatic Brain Injury: A TRACK-TBI Study
CONCLUSIONS: Obesity and comorbidity profiles are associated with an inflammatory response with the potential to impact recovery; consideration of systemic health at the time of injury could improve recovery.
Basic Science and Pathogenesis
CONCLUSION: These data identify sex differences in the extent of axonal pathologies in brain white matter acutely after TBI, which appears related to sex differences in axon diameter. Notably, these findings further shed light on insights that damaged and degenerating axons following TBI may provide a rich source of APP/Aβ as pathologic substrate contributing to […]
Extracranial Hemodynamic Responses to a Noxious Cold Pressor Task Differ Between Persistent Post-Traumatic Headache and Healthy Controls
Background/Objectives: Headache after a traumatic brain injury (TBI) is one of the most common post-concussive symptoms and is associated with altered pain processing and elevated disability levels. Understanding physiologic correlates of nociception in individuals with persistent post-traumatic headache (pPTH) may help identify novel treatment targets for pain-related disability. The objective of this case-control study was […]
The relationship between dispositional mindfulness and psychological, cognitive, and functional outcomes following mild traumatic brain injury
Background: Most individuals who sustain a mild uncomplicated Traumatic Brain Injury (mTBI) recover within 1-3 months. However, a significant proportion consistently report ongoing cognitive, psychological, and somatic sequelae, which can be functionally disabling and hinder active participation in society following injury. The present study examined dispositional mindfulness as a targetable protective factor as it pertains […]