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"Insights into mTBI, PCS, and FND — One Synapse at a Time" A bit more creative, nodding to neuroscience roots while covering your full range.
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brain health

  • Functional neurological disorders

    Pharmaco-psychiatry and gut microbiome: a systematic review of effects of psychotropic drugs for bipolar disorder

    by myneuronews June 18, 2025
    by myneuronews June 18, 2025

    Pharmaco-psychiatric Mechanisms The intricate relationship between psychotropic medications and neuropsychiatric outcomes has attracted significant interest …

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  • Traumatic brain injury

    The Acute Effects of Non-concussive Head Impacts on Brain Microstructure, Chemistry and Function in Male Soccer Players: A Pilot Randomised Controlled Trial

    by myneuronews June 18, 2025
    by myneuronews June 18, 2025

    Study Overview This pilot randomized controlled trial set out to investigate the immediate effects of …

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  • Traumatic brain injury

    The Acute Effects of Non-concussive Head Impacts on Brain Microstructure, Chemistry and Function in Male Soccer Players: A Pilot Randomised Controlled Trial

    by myneuronews June 18, 2025
    by myneuronews June 18, 2025

    Study Overview The research explores the immediate impacts of non-concussive head impacts on the brains …

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  • Functional neurological disorders

    Altered Microglial Plasticity in the Periaqueductal Grey of Pre-Symptomatic Mecp2-Heterozygous Mice Following Early-Life Stress

    by myneuronews June 17, 2025
    by myneuronews June 17, 2025

    Microglial Plasticity Changes Microglia, the immune cells of the central nervous system, play a crucial …

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  • Traumatic brain injury

    Neuroimaging of Mild Traumatic Injury

    by myneuronews June 17, 2025
    by myneuronews June 17, 2025

    Neuroimaging Techniques Neuroimaging plays a pivotal role in the assessment and understanding of mild traumatic …

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  • Functional neurological disorders

    Insights into insulin signalling and oxidative stress in the Tg2576 mouse model of familial Alzheimer’s disease: effects of chronic oral galactose administration

    by myneuronews June 16, 2025
    by myneuronews June 16, 2025

    Insulin Signalling Pathways in Alzheimer’s Disease Insulin signalling pathways play a crucial role in numerous …

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  • Functional neurological disorders

    Insights into insulin signalling and oxidative stress in the Tg2576 mouse model of familial Alzheimer’s disease: effects of chronic oral galactose administration

    by myneuronews June 16, 2025
    by myneuronews June 16, 2025

    Insulin Signalling Pathways in Alzheimer’s Disease The role of insulin signalling pathways in Alzheimer’s disease …

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  • Functional neurological disorders

    Brain-Specific Gata4 Downregulation in Greywick Female Mice Models the Metabolic Subtype of Polycystic Ovary Syndrome

    by myneuronews June 14, 2025
    by myneuronews June 14, 2025

    Brain-Specific Gata4 Function in Metabolism Gata4 is a transcription factor known for its critical roles …

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  • Dementia

    Retinal degeneration as an initial manifestation in a patient with neuronal intranuclear inclusion disease

    by myneuronews June 14, 2025
    by myneuronews June 14, 2025

    Background of Retinal Degeneration Retinal degeneration encompasses a range of conditions characterized by the progressive …

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  • Traumatic brain injury

    Understanding Beliefs and Perceptions of Parents, Coaches, and Organizational Leaders toward Non-concussive Head Impact Exposure in Youth American Football

    by myneuronews June 13, 2025
    by myneuronews June 13, 2025

    Understanding Head Impact Exposure In youth American football, the term “head impact exposure” refers to …

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  • Sildenafil provokes headache but not migraine in men with migraine without aura: a randomized, placebo-controlled crossover trial
    Study Overview The research aimed to investigate the effects of sildenafil, a phosphodiesterase type 5…
  • Associations of Lifetime Cumulative Estrogen Exposure with Lifecourse Social Exposures, Cognitive Decline, and Dementia Risk Among Postmenopausal White, Black, and Latina Women
    Lifetime Estrogen Exposure and Cognitive Health Lifetime estrogen exposure has emerged as a significant factor…
  • Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
    Incretin Mimetics Mechanism of Action Incretin mimetics are agents that are designed to mimic the…
  • N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
    Study Overview This investigation focuses on the effects of N-stearidonoylethanolamine (NSE) in addressing synaptic deficits…
  • Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
    Study Overview This study investigates the long-term effects of persistent post-concussion symptoms (PPCS) on various…

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Research

  • Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
    Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
  • N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
    Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
  • Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
    CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
  • Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
    CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
  • Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
    Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]

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