CD300f enables microglial damage sensing, efferocytosis, and apoptotic cell metabolization after brain injury
Microglial Function in Brain Injury Microglia, the primary immune cells of the central nervous system, play a crucial role in […]
Boston University Alzheimer’s Disease Research Center Clinical Core: Infrastructure to facilitate research on post-traumatic Alzheimer’s disease and related dementias
Research Objectives The primary aim of the Boston University Alzheimer’s Disease Research Center’s Clinical Core is to advance our understanding
Progressive lifespan modifications in the corpus callosum following a single concussion in juvenile male mice monitored by diffusion MRI
Study Overview The investigation aimed to explore the long-term impacts of a single concussion on the corpus callosum in juvenile
Retinal Layer Thickness and Volume Measurements in Traumatic Brain Injury
Retinal Layer Measurements in Brain Injury In the context of traumatic brain injury (TBI), understanding the structural changes that occur
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Association Between Dietary Biotin Intake and Dementia Risk, Including Alzheimer’s Disease: A Prospective Study of 122 959 UK Biobank Participants
Background and Objectives The relationship between nutrition and cognitive health has garnered increasing attention in recent years, particularly as the
Enriched Environment Alleviate AD Pathological Progression by Reducing Microglia Complement Signaling in Aged Male APP/PS1 Mice
Study Overview This research investigates the impact of enriched environments on Alzheimer’s disease (AD) progression in aged male APP/PS1 mice,
The Role of MRI in Debunking the Fallacy of “Mild” Traumatic Brain Injury
The Importance of MRI in TBI Assessment Magnetic Resonance Imaging (MRI) plays a pivotal role in the evaluation of traumatic
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Longitudinal Effects of Mild Traumatic Brain Injury on the Gut Microbiome and Acoustic Startle Response in Male and Female Rats
Study Overview This research investigates the consequences of mild traumatic brain injury (mTBI) on both the gut microbiome and the
Reduced Masseter Muscle Area Predicts the 6-Month Outcome After Mild Traumatic Brain Injury in Older Adults
Background and Rationale Mild traumatic brain injury (mTBI), often referred to as a concussion, is a significant public health issue,
Recurrent spaced concussions in adolescent rats disrupt cortical dopaminergic markers and induce behavioral hyperactivity and impaired object location memory
Study Overview The study investigates the effects of recurrent concussions on brain chemistry and behavior in adolescent rats. Concussions, particularly