Tag:

brain health

Dementia
Estimated Glucose Disposal Rate and Risk of Stroke and Dementia in Nondiabetics: A UK Biobank Prospective Cohort Study

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Study Overview The investigation centered around the relationship between glucose disposal rate and the risk …

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Traumatic brain injury
CD300f enables microglial damage sensing, efferocytosis, and apoptotic cell metabolization after brain injury

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Microglial Function in Brain Injury Microglia, the primary immune cells of the central nervous system, …

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Traumatic brain injury
Boston University Alzheimer’s Disease Research Center Clinical Core: Infrastructure to facilitate research on post-traumatic Alzheimer’s disease and related dementias

by myneuronews September 9, 2025

by myneuronews September 9, 2025

Research Objectives The primary aim of the Boston University Alzheimer’s Disease Research Center’s Clinical Core …

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Traumatic brain injury
Progressive lifespan modifications in the corpus callosum following a single concussion in juvenile male mice monitored by diffusion MRI

by myneuronews September 9, 2025

by myneuronews September 9, 2025

Study Overview The investigation aimed to explore the long-term impacts of a single concussion on …

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Traumatic brain injury
Retinal Layer Thickness and Volume Measurements in Traumatic Brain Injury

by myneuronews September 8, 2025

by myneuronews September 8, 2025

Retinal Layer Measurements in Brain Injury In the context of traumatic brain injury (TBI), understanding …

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Dementia
Association Between Dietary Biotin Intake and Dementia Risk, Including Alzheimer’s Disease: A Prospective Study of 122 959 UK Biobank Participants

by myneuronews September 7, 2025

by myneuronews September 7, 2025

Background and Objectives The relationship between nutrition and cognitive health has garnered increasing attention in …

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Dementia
Enriched Environment Alleviate AD Pathological Progression by Reducing Microglia Complement Signaling in Aged Male APP/PS1 Mice

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Study Overview This research investigates the impact of enriched environments on Alzheimer’s disease (AD) progression …

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Traumatic brain injury
The Role of MRI in Debunking the Fallacy of “Mild” Traumatic Brain Injury

by myneuronews September 5, 2025

by myneuronews September 5, 2025

The Importance of MRI in TBI Assessment Magnetic Resonance Imaging (MRI) plays a pivotal role …

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Traumatic brain injury
Longitudinal Effects of Mild Traumatic Brain Injury on the Gut Microbiome and Acoustic Startle Response in Male and Female Rats

by myneuronews September 3, 2025

by myneuronews September 3, 2025

Study Overview This research investigates the consequences of mild traumatic brain injury (mTBI) on both …

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Traumatic brain injury
Reduced Masseter Muscle Area Predicts the 6-Month Outcome After Mild Traumatic Brain Injury in Older Adults

by myneuronews September 2, 2025

by myneuronews September 2, 2025

Background and Rationale Mild traumatic brain injury (mTBI), often referred to as a concussion, is …

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A sensor-based gait measure for identifying invalid performance in simulated mTBI: an experimental proof of concept
CONCLUSIONS: Findings offer preliminary support for the ability of an automated gait-based measure to capture invalid performance and inform investigations regarding effort. These experimental findings represent a first step in exploring the potential clinical utility of the BKG as a measure of performance validity.
The clinical and cost-effectiveness of sertraline in preventing depression in adults following a traumatic brain injury (STOP-D): study protocol for a multi-centre randomised controlled trial
BACKGROUND: Traumatic brain injury (TBI) is a common presentation in emergency departments worldwide. Approximately 1.4 million adults present with TBI in England and Wales annually. Post-TBI depression (PTD) is a common neuropsychiatric consequence, affecting up to 50% of patients within two years, and is associated with adverse functional outcomes. PTD remains underdiagnosed and undertreated. Sertraline, […]
The Relationship of Prior Concussion and Contact Sport Exposure With Cortical Macro and Microstructure
Changes in cortical gray matter are a key feature of neurodegenerative diseases that have been linked with concussion and repetitive head impacts (RHIs). Prior evidence implicates prior concussion and RHI in reduced cortical thickness or volume in temporal and frontal regions, with results largely restricted to older retired contact sport athletes. Fewer studies have investigated […]
Impact of Modified Brain Injury Guideline Incorporating Neurosurgical Consultation on Resource Utilization and Follow-Up Care in Complicated Mild Traumatic Brain Injury
CONCLUSION: Implementation of a resource utilization-focused protocol at our trauma center incorporating neurosurgery consultation for patients with complicated mTBI led to higher rates of direct discharges from the ED and to home without compromising TBI-related follow-up care. Results demonstrate that adoption of a modified BIG protocol that includes neurosurgical collaboration can translate to more efficient […]
Timing of definitive fracture fixation in patients with concomitant traumatic brain injuries - A systematic review of the literature by the IMPACT group
CONCLUSIONS: Early definitive fracture fixation within 24 h should be attempted in polytrauma patients with concomitant mild TBI under specific conditions, which were previously defined by the IMPACT group. Furthermore, current evidence suggests that this approach is both safe and beneficial in a carefully selected patient population. In cases of moderate and severe TBI, decision-making […]