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brain injury

Traumatic brain injury
Concussive injuries induce neuronal stress-dependent tau mislocalization to dendritic spines with acrolein and functional network alteration in TBI-on-a-chip

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Study Overview This research focuses on the cellular mechanisms involved in concussive injuries, specifically examining …

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Traumatic brain injury
Quantifying Longitudinal Microstructural Changes in Mild Traumatic Brain Injury Patients with Mean Apparent Propagator MRI

by myneuronews September 10, 2025

by myneuronews September 10, 2025

Study Overview This study investigates the microstructural changes in brain tissue associated with mild traumatic …

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Traumatic brain injury
Burden of Intracranial Hypertension and Patterns of Brain Injury on MRI: Secondary Analysis of the 2014-2017 “Approaches and Decisions for Acute Pediatric TBI” Study

by myneuronews September 10, 2025

by myneuronews September 10, 2025

Burden of Intracranial Hypertension Intracranial hypertension, characterized by elevated pressure within the skull, presents a …

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Dementia
Boston University Alzheimer’s Disease Research Center Clinical Core: Infrastructure to facilitate research on post-traumatic Alzheimer’s disease and related dementias

by myneuronews September 9, 2025

by myneuronews September 9, 2025

Research Objectives The primary aim of the Boston University Alzheimer’s Disease Research Center Clinical Core …

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Traumatic brain injury
A machine learning approach to concussive group classification using discrete outcome measures from a low-cost movement-based assessment system

by myneuronews September 9, 2025

by myneuronews September 9, 2025

Overview of Concussive Classification Concussion, a type of traumatic brain injury, poses significant challenges for …

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Traumatic brain injury
Progressive lifespan modifications in the corpus callosum following a single concussion in juvenile male mice monitored by diffusion MRI

by myneuronews September 9, 2025

by myneuronews September 9, 2025

Study Overview The investigation aimed to explore the long-term impacts of a single concussion on …

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Traumatic brain injury
Sensory processing patterns in pediatric mild traumatic brain injury: A longitudinal study

by myneuronews September 9, 2025

by myneuronews September 9, 2025

Study Overview The research focused on how sensory processing patterns change over time in children …

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Traumatic brain injury
Boston University Alzheimer’s Disease Research Center Clinical Core: Infrastructure to facilitate research on post-traumatic Alzheimer’s disease and related dementias

by myneuronews September 9, 2025

by myneuronews September 9, 2025

Research Objectives The primary aim of the Boston University Alzheimer’s Disease Research Center’s Clinical Core …

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Traumatic brain injury
Retinal Layer Thickness and Volume Measurements in Traumatic Brain Injury

by myneuronews September 8, 2025

by myneuronews September 8, 2025

Retinal Layer Measurements in Brain Injury In the context of traumatic brain injury (TBI), understanding …

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Traumatic brain injury
A prolyl oligopeptidase ligand blocks memory deficit in a repeated mild traumatic brain injury model

by myneuronews September 8, 2025

by myneuronews September 8, 2025

Study Overview This research investigates the role of a prolyl oligopeptidase (POP) ligand in the …

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Non-invasive vagus nerve stimulation is associated with the reduction in persistent post-concussion symptoms: an observational study
INTRODUCTION: Traumatic brain injury (TBI) remains a major public health challenge, with mild TBI (mTBI) frequently resulting in persistent cognitive, affective, and somatic symptoms. Non-invasive vagus nerve stimulation (nVNS) has demonstrated potential in reducing neuroinflammation and promoting recovery in preclinical TBI models. This retrospective, observational study assessed the impact of adjunctive nVNS on postconcussive symptoms […]
Spautin-1 alleviates depression-like behaviors in mice after traumatic brain injury by inhibiting MMP3 expression in microglia in the Hippocampal CA1 region
CONCLUSIONS: Spautin-1 alleviates depression-like behaviors in mice following mild TBI by inhibiting the MMP3 signaling pathway in microglia within the CA1 region of the hippocampus, indicating a potential therapeutic strategy for addressing post-TBI depression.
Concussive injuries induce neuronal stress-dependent tau mislocalization to dendritic spines with acrolein and functional network alteration in TBI-on-a-chip
Traumatic brain injuries (TBIs) are a risk factor for Alzheimer's disease (AD), and share several important pathological features including the development of neurofibrillary tangles (NFT) of tau protein. While this association is well established, the underlying pathogenesis is poorly defined and current treatment options remain limited, necessitating novel methods and approaches. In response we developed […]
Detecting mild traumatic brain injury with MEG scan data: One-vs-K-sample tests
Magnetoencephalography (MEG) scanner has been shown to be more accurate than other medical devices in detecting mild traumatic brain injury (mTBI). However, MEG scan data in certain spectrum ranges can be skewed, multimodal, and heterogeneous which can mislead the conventional case-control analysis that requires the data to be homogeneous and normally distributed within the control […]
Risk of Mortality Among Adult Females Diagnosed with Traumatic Brain Injury in an Academic Medical System
The objective of this retrospective cohort study was to evaluate mortality risk over five years among 6,432 female patients with a health care encounter diagnosis of TBI from hospitals and outpatient clinics within a university health system. We used TBI severity, defined by the Centers for Disease Control and Department of Defense/Veterans Affairs: mild, moderate/severe/penetrating, […]