Tag:

brain injury

Traumatic brain injury
Sex-dependent blood-brain barrier alterations following repeated mild blast traumatic brain injury at varying inter-injury intervals

by myneuronews June 1, 2025

by myneuronews June 1, 2025

Study Overview The investigation focused on the impact of repeated mild blast traumatic brain injuries …

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Traumatic brain injury
Single-nucleus and spatial signatures of the brainstem in normal brain and mild traumatic brain injury in male mice

by myneuronews May 31, 2025

by myneuronews May 31, 2025

Study Overview This investigation delves into the complexities of brainstem alterations in male mice, specifically …

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Traumatic brain injury
Single-nucleus and spatial signatures of the brainstem in normal brain and mild traumatic brain injury in male mice

by myneuronews May 31, 2025

by myneuronews May 31, 2025

Study Overview The research investigates the brainstem’s cellular and molecular properties in male mice, specifically …

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Dementia
Study of the Spectrum of Treatable Dementias: Insights from a Large South Asian Cohort (TREAT-Dem Study)

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Overview of Treatable Dementias Dementia encompasses a variety of cognitive impairments caused by different medical …

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Stroke
Research status and future perspectives of IL-27 in the treatment of stroke (Review)

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Current Understanding of IL-27 in Stroke Interleukin-27 (IL-27) is a cytokine that belongs to the …

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Traumatic brain injury
Epidemiology of Traumatic brain injury in Ethiopia: A systematic review and meta-analysis of prevalence, mechanisms, and outcomes

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Epidemiological Context The burden of traumatic brain injury (TBI) in Ethiopia represents a significant public …

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Traumatic brain injury
Post-Concussion Changes in the Functional Brain Connectome Relative to Pre-Injury Baseline: A Prospective Observational Study

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Study Overview This research investigates alterations in the functional connectivity of the brain before and …

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Traumatic brain injury
Combination Therapy of Estrogen and Progesterone Attenuates Behavioral Impairments and Autophagy via circLrp1b/miR-27a-3p/Dram2 Pathway After Traumatic Brain Injury

by myneuronews May 29, 2025

by myneuronews May 29, 2025

Study Overview The research investigates the effects of combination therapy involving estrogen and progesterone in …

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Traumatic brain injury
Elevation of C-reactive protein and homocysteine levels as reliable biomarkers for assessing injury severity and prognosis in traumatic brain injury

by myneuronews May 29, 2025

by myneuronews May 29, 2025

Biomarkers in Traumatic Brain Injury In the context of traumatic brain injury (TBI), biomarkers serve …

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Traumatic brain injury
Combination Therapy of Estrogen and Progesterone Attenuates Behavioral Impairments and Autophagy via circLrp1b/miR-27a-3p/Dram2 Pathway After Traumatic Brain Injury

by myneuronews May 29, 2025

by myneuronews May 29, 2025

Study Overview The research investigates the effects of combination therapy involving estrogen and progesterone on …

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Understanding factors influencing the return to physical activity, perspectives of adults with concussion/mild traumatic brain injury: A qualitative study
Understanding the factors that influence the return to physical activity can help to modify behaviour to enhance the recovery of symptoms and physical activity. We conducted 14 semi-structured interviews to explore the barriers and facilitators to returning to physical activity in adults following a mild traumatic brain injury (TBI). The study design was informed by […]
Clinical Utility of the Sport Concussion Office Assessment Tool 6 (SCOAT6) and Other Select Multidomain Assessments for Subacute Sport-Related Concussion
CONCLUSIONS: The PCSI, timed tandem gait, and mVOMS components of the SCOAT6 were useful in identifying sport-related concussion. However, verbal cognitive tests, orthostatic vital signs, and clinical balance components were not useful for this purpose. The CP Screen, additional items from the full version of the VOMS, and ImPACT memory and processing speed were also […]
Persistent Post-concussion syndrome: pathophysiology, diagnosis, current and evolving treatment strategies
INTRODUCTION: Persistent post-concussion syndrome (PCS) following mild traumatic brain injury (mTBI) represents a growing global health challenge that significantly impacts patients' quality of life. Despite advances in acute concussion management, there remains a critical need for effective, evidence-based treatments for chronic PCS, as current interventions show limited success in addressing both symptoms and underlying pathophysiology.
Time-limited association between plasma transfusion and mortality in pediatric traumatic brain injury
CONCLUSION: This study reports a significant association between early plasma administration and a lower risk of 4-hour mortality among children with severe TBI that does not persist at or beyond 24 hours. While these data suggest that plasma resuscitation may extend the window for lifesaving intervention, additional prospective data are needed.
Comparing the sensitivity and specificity of novel motor assessments for traumatic brain injury
CONCLUSION: MMC-mediated tests are sensitive and specific (compared to traditional clinical tests) and have potential to fill a gap in clinical care of TBI.