Tag:

brain trauma

Traumatic brain injury
Inhibition of microglia priming by NLRP3 reduces the impact of early life stress and mild TBI

by myneuronews July 17, 2025

by myneuronews July 17, 2025

Study Overview The objective of the research was to investigate how inhibiting the activation of …

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Traumatic brain injury
MILD TRAUMATIC BRAIN INJURY IMPAIRS EPISODIC MEMORY IN RATS

by myneuronews July 14, 2025

by myneuronews July 14, 2025

Study Overview The research investigates how mild traumatic brain injury (mTBI) affects episodic memory in …

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Traumatic brain injury
Aldehydic load as an objective imaging biomarker of mild traumatic brain injury

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Aldehydic Load Measurement The measurement of aldehydic load plays a crucial role in understanding the …

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Traumatic brain injury
Proposed Reformulation of Brain Injury Criteria (BrIC) Using Head Rotation-Induced Brain Injury Thresholds Simulated and Derived Directly from A Subhuman Primate Finite Element Model

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview The investigation presented in this study focuses on redefining the criteria for brain …

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Traumatic brain injury
Biomarker evidence of neurodegeneration in mid-life former rugby players

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Neurodegeneration Biomarkers Biomarkers indicative of neurodegeneration are crucial for understanding the underlying processes affecting brain …

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Traumatic brain injury
Differential DNA Methylation of the Brain-Derived Neurotrophic Factor Gene is Observed after Pediatric Traumatic Brain Injury Compared to Orthopedic Injury

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Study Overview The study investigates the differential methylation patterns of the brain-derived neurotrophic factor (BDNF) …

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Traumatic brain injury
Pituitary Dysfunction Following Mild Traumatic Brain Injury in Female Athletes: Neuropsychological and Psychological Findings

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Study Overview The investigation focuses on the impact of mild traumatic brain injuries (mTBI) on …

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Traumatic brain injury
Exercise plasma improves traumatic brain injury outcomes in mice

by myneuronews May 23, 2025

by myneuronews May 23, 2025

Effects of Exercise Plasma on Brain Injury Research has shown that exercise can have profound …

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Traumatic brain injury
Single-Cell RNA and Transcriptome Sequencing to Analyze the Role of Lactate Metabolism in Traumatic Brain Injury Astrocytes

by myneuronews May 21, 2025

by myneuronews May 21, 2025

Role of Lactate Metabolism in Astrocytes Lactate metabolism plays a pivotal role in cellular energy …

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Traumatic brain injury
Genome-wide analysis of lncRNA m6A methylation in the mouse cortex after repetitive mild traumatic brain injury

by myneuronews May 20, 2025

by myneuronews May 20, 2025

Background on lncRNA and m6A Methylation Long non-coding RNAs (lncRNAs) are an intriguing class of …

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Autologous bone marrow mononuclear cell administration for neurological sequelae after traumatic brain injury: a matched control study
Neurological sequelae after traumatic brain injury impair motor and behavioural functions, imposing a heavy burden on patients and society. Traditional treatments show limited efficacy, highlighting the need for advanced therapies. This study evaluated the safety and efficacy of intrathecal administration of bone marrow mononuclear cells for treating these sequelae. A matched control clinical trial was […]
Concussion Classification in a Multicenter Patient Cohort: The Updated ACRM Diagnostic Criteria and Concordance With Physician Impression of Injury
CONCLUSION: Use of the ACRM criteria clinically to determine if an injury qualifies as mTBI may be less susceptible to bias from ongoing symptom reporting than the physician impression of the injury.
Immediate Postoperative Virtual Reality Therapy for Phantom Limb Pain in Multiextremity Amputees: A Report of 3 Cases
CONCLUSION: These cases demonstrate that VR can be safely and effectively implemented postoperatively following multiextremity amputation, suggesting potential for expanded use even in similarly complex cases.
Elastin-like polypeptide delivery of an NF-kB inhibitor for treatment of juvenile mild TBI complicated by high-fat diet consumption
Juveniles are at increased risk for mild traumatic brain injury (mTBI) due to recreational activities, domestic violence, and vulnerabilities of the developing skull. In industrialized nations, adolescents often consume high-sugar, high-fat diets (HFD), which can impair CNS health and exacerbate mTBI outcomes. Secondary injury following mTBI is characterized by prolonged neuroinflammation, with nuclear factor kappa […]
Exercise-induced molecular modulation following mTBI: A multi-omics study in male mice
Mild traumatic brain injury (mTBI) poses a significant clinical challenge, often resulting in persistent cognitive and neurological impairments. This study investigates the therapeutic effects of a 17-day running protocol on mTBI recovery in male mice. Using a weight-drop mTBI model, proteomics and RNA-sequencing analyses were conducted at acute (19 days post-injury) and chronic (47 days […]