PTSD and Audio Vestibular Symptoms: A Two-Way Street Driven by the Amygdala A Speculative Hypothesis
Understanding The Amygdala’s Role The amygdala, a small almond-shaped cluster of nuclei located deep within the temporal lobes of the […]
Pontine pathology mediates common symptoms of blast-induced chronic mild traumatic brain injury
Pontine Pathology and Symptoms The pontine region of the brainstem plays a crucial role in numerous functions, including the regulation
Update on the Pathophysiology and Management of Tics
Pathophysiology of Tics Tics are characterized by sudden, repetitive movements or sounds that are involuntary, arising from a complex interplay
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The NERD model: reflex circuit dysfunction as a systems-level driver of persistent post-concussion symptoms
Reflex Circuit Dysfunction in Post-Concussion Symptoms Following a concussion, some individuals experience persistent symptoms that may be attributed to dysfunction
The NERD model: reflex circuit dysfunction as a systems-level driver of persistent post-concussion symptoms
Reflex Circuit Dysfunction Reflex circuits play a crucial role in the central nervous system, integrating sensory inputs and generating appropriate
Herpes simplex virus associated rhomboencephalitis mimicking demyelination: a case report
Study Overview This case report focuses on a unique instance of rhomboencephalitis, an inflammation of the brain that can present
Microsurgical Management of Anterior Inferior Cerebellar Artery Aneurysms: Case Series and Review of Advanced Imaging and Cranial Base Approaches
Background and Significance Aneurysms associated with the anterior inferior cerebellar artery (AICA) are relatively rare but carry significant risks, including
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury
Distinct Clinical Phenotypes Chronic traumatic brain injury (TBI) presents a spectrum of clinical phenotypes, each exhibiting unique behavioral, cognitive, and
Widespread and cell-type-specific transcriptomic reorganization following mild traumatic brain injury
Transcriptomic Changes Induced by Injury Mild traumatic brain injury (mTBI) triggers significant changes in the brain’s transcriptome, the complete set
Understanding “Internal Fake News”: The Link Between Concussion, Sensory Alterations, and Emotional Health
Concussions and post-concussion symptoms significantly impact the brain’s ability to process and integrate sensory information, leading to a phenomenon termed “internal fake news.” This occurs when altered sensory perceptions distort internal models, affecting decision-making and leading to a cascade of negative consequences including chronic stress, anxiety, and depression. The cerebellum’s role in integrating multisensory information is crucial for updating these internal models accurately. Disruptions in this process, commonly seen in concussion patients, result in a vicious cycle of emotional disturbances. Early intervention and a multidisciplinary approach are essential for mitigating these effects and supporting recovery.