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clinical challenges

Functional neurological disorders
Aggressive and Refractory Attack of AQP4-IgG-Positive Neuromyelitis Optica Spectrum Disorder Treated With Ravulizumab: A Case Report

by myneuronews May 22, 2025

by myneuronews May 22, 2025

Clinical Presentation and Diagnosis In this case report, the patient presented with symptoms characteristic of …

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Functional neurological disorders
Distinguishing Functional Neurological Disorder from Malingering or Feigning

by Ioannis Mavroudis April 21, 2024

by Ioannis Mavroudis April 21, 2024

Functional Neurological Disorder (FND) presents a frontier of exploration in neurological and psychiatric disciplines, where …

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Development of chronic subdural haematoma from mild head injury: A case report and review of current Malaysian guidelines on traumatic brain injury
Delayed chronic subdural haematoma (cSDH) is a common but potentially serious complication following traumatic brain injury (TBI). Mild TBIs are commonly managed by primary care providers (PCPs), particularly in large, resource-limited settings such as Malaysia, where access to tertiary neurosurgical services may be delayed. Early identification of red-flag signs and symptoms and timely referrals are […]
Cognitive Proficiency after Traumatic Brain Injury in Children
Fifty-five children and adolescents with complicated mild-severe traumatic brain injury (TBI) completed the Wechsler Intelligence Scale for Children-Fifth Edition (WISC-V; Wechsler, 2014) within 1 to 12 months post-injury. Compared with demographically matched neurologically healthy controls, selected from the WISC-V standardization sample, participants with TBI demonstrated statistically significantly lower scores across WISC-V indices. The working memory, […]
Implementing Goal Attainment Scaling as a Person-Centered Measurement Tool to Direct Care and Evaluate Outcomes in Neurorehabilitation Settings
The purpose of this Special Communication is to describe barriers and facilitators to implementing goal attainment scaling (GAS) as a patient-centered measurement tool in neurorehabilitation settings. The experiences of three distinct neurorehabilitation settings that implemented GAS to enhance person-centered care and measure person-centered goal attainment are described: a neurorehabilitation service at an inpatient rehabilitation facility; […]
Construct Validity of the Tower of London Test: Generating a Construct Specification Equation Relating Problem Characteristics to Problem Difficulty in a Sample of Veterans with Mild Traumatic Brain Injury
The Tower of London (TOL) is a set of problem-solving tasks that are commonly used to measure cognition. No studies have developed construct specification equations (CSEs) to mathematically quantify how the characteristics of test problems relate to the difficulty of the problem in the TOL. We aimed to investigate the relationship between TOL problem characteristics […]
Vibrational spectroscopy methods reveal biochemical changes associated with the glial scar formation after traumatic brain injury
Traumatic brain injury (TBI) is a serious clinical and social problem. Millions of TBI cases, that require hospitalization and consequently burden social security systems, are reported each year. Analysis of the time course of changes that occur in the brain after primary injury may help indicate therapeutic goals and treatment directions that will minimize severe […]

clinical challenges

Aggressive and Refractory Attack of AQP4-IgG-Positive Neuromyelitis Optica Spectrum Disorder Treated With Ravulizumab: A Case Report

Distinguishing Functional Neurological Disorder from Malingering or Feigning