Tag:

clinical evaluation

Traumatic brain injury
Optimal Diagnostic Strategies for Concussion-Related Vision Disorders: A Review

by myneuronews May 19, 2025

by myneuronews May 19, 2025

Understanding Concussion-Related Vision Disorders Concussion-related vision disorders encompass a range of visual symptoms that can …

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Dementia
Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer’s Disease

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Treatment Strategy Overview In recent years, the exploration of innovative approaches to treat Alzheimer’s disease …

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Traumatic brain injury
No Association Between Fencing Response After Concussion and Recovery Time, Concussion Severity, or Clinical Outcomes in Professional American Football Players

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview This research investigates the relationship between the fencing response observed in athletes following …

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Headaches
Efficacy, safety, and tolerability of chenodeoxycholic acid (CDCA) in adult patients with cerebrotendinous xanthomatosis (RESTORE): a randomized withdrawal, double-blind, placebo-controlled, crossover phase 3 study

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Efficacy of Chenodeoxycholic Acid Chenodeoxycholic acid (CDCA) has emerged as a critical therapeutic option for …

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Medical professionals Traumatic brain injury
Latest guidelines for mild traumatic brain injury assessment

by Ioannis Mavroudis April 28, 2025

by Ioannis Mavroudis April 28, 2025

Mild traumatic brain injury, commonly known as concussion, involves subtle yet significant disruptions to brain …

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Traumatic brain injury
Computed Tomography Findings of Children Under 3 Years of Age with Mild Traumatic Brain Injury (TBI) and No Neurological Focal Signs

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Computed Tomography Characteristics Computed tomography (CT) plays a crucial role in evaluating pediatric patients with …

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Traumatic brain injury
Clinical manifestations and treatment of hypopituitarism due to traumatic brain injury

by myneuronews April 25, 2025

by myneuronews April 25, 2025

Understanding Hypopituitarism Hypopituitarism is a condition characterized by the insufficient production of one or more …

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Traumatic brain injury
Differentiating Between Concussion, Psychological Symptoms, and Malingering Using the ImPACT Test

by Ioannis Mavroudis June 25, 2024

by Ioannis Mavroudis June 25, 2024

The Immediate Post-Concussion Assessment and Cognitive Testing (ImPACT) is a vital tool in the assessment …

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National and subnational burden of neurological disorders in Iran, 1990 to 2021: results from the global burden of disease study 2021
Burden of Neurological Disorders in Iran The landscape of neurological disorders in Iran presents a…
Nuclear membrane disruption in neurodegenerative diseases: Emerging perspectives
Nuclear membrane function in neuronal health The nuclear membrane, or nuclear envelope, is a critical…
Cognitive impairment and altered structural connectivity after mild traumatic brain injury: A longitudinal study based on generalized q-sampling imaging
Cognitive Impairment Assessment The assessment of cognitive impairment following mild traumatic brain injury (mTBI) is…
Prevalence and Risk of Anxiety and Depression after Concussion: A TRANSCENDENT Study
Study Overview The investigation focused on the prevalence and risk factors associated with anxiety and…
Inhibition of p38 MAPK after repetitive mTBI ameliorates immune signaling and functional deficits
Study Overview This study investigates the effects of inhibiting p38 MAPK (mitogen-activated protein kinase) following…

Severity of physical, emotional, and cognitive symptoms is associated with future persistence of acute post-traumatic headache attributed to mild traumatic brain injury
AimPost-traumatic headache (PTH) attributed to mild traumatic brain injury (mTBI) frequently co-occurs with other physical, cognitive, and emotional symptoms. This study assessed associations between PTH improvement and these symptoms in individuals with acute headaches (APTH) and compared symptoms between those who had recently developed persistent PTH (PPTH) to those who had long-standing PPTH.MethodsThis study included […]
NSAID Use Is Not Associated With Persisting Symptoms in Adolescent Concussion
CONCLUSIONS: In adolescents, NSAID use was associated with more severe symptoms but not PSaC. To optimize clinical guidance, future research should further evaluate the role of NSAIDs in concussion recovery.
Systemic inflammation and its associations in acute moderate-severe Traumatic Brain Injury: a cross-sectional study
Traumatic Brain Injury (TBI) triggers an acute systemic inflammatory response, which may impact outcomes. This response may interact with pre-existing factors linked to inflammation, such as age, to influence outcomes. Previous studies have typically measured few cytokines, but high-dimensional proteomic approaches can sensitively detect a broad range of inflammatory markers, to better characterise post-TBI inflammation. […]
Reduced cortical excitability is associated with head impact severity and cognitive symptoms in adolescent football players
American tackle football is associated with high rates of concussion, leading to neurophysiological disturbances and debilitating clinical symptoms, but previous investigations have largely ignored aperiodic neurophysiological activity. In this study, we use pre- and post-season resting-state magnetoencephalography (MEG) to examine whether concussion during a season of football is related to changes in neurophysiology and whether […]
Sex hormone dysregulation after traumatic brain injury: interactions with sleep disturbances and seizure susceptibility
Each year, approximately 2.9 million people in the United States sustain a traumatic brain injury (TBI), many of whom go on to experience chronic secondary complications such as post-traumatic epilepsy (PTE) and sleep-wake disturbances. These outcomes arise from complex secondary injury processes, including neuroinflammation, oxidative stress, and disruptions in neuroendocrine signaling. While inflammatory and excitotoxic […]