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clinical management

Functional neurological disorders
Seizures and Functional Deficits across Mendelian Disorders of Epigenetic Machinery: Differential Effects as a Function of Epigenetic Modifications

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Understanding Mendelian Disorders Mendelian disorders are genetic conditions resulting from mutations in a single gene …

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Functional neurological disorders
Connectogram-COH: A Coherence-Based Time-Graph Representation for EEG-Based Alzheimer’s Disease Detection

by myneuronews June 13, 2025

by myneuronews June 13, 2025

Coherence-Based Time-Graph Representation The study introduces an innovative approach for representing and analyzing EEG data …

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Headaches
A neglected zoonotic helminth-Hymenolepis nana, fatal in the pediatric population-an incidental finding

by myneuronews June 9, 2025

by myneuronews June 9, 2025

Understanding Hymenolepis nana Hymenolepis nana, commonly referred to as the dwarf tapeworm, is a small …

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Headaches
Long-term outcomes in leucine-rich glioma inactivated-1 autoimmune encephalitis and associated biomarkers of inflammation and neuronal and glial injury

by myneuronews June 5, 2025

by myneuronews June 5, 2025

Long-term outcomes Long-term outcomes in patients with leucine-rich glioma inactivated-1 (LGI1) autoimmune encephalitis are a …

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Traumatic brain injury
Spontaneous postpartum recovery of mild traumatic brain injury induced growth hormone deficiency

by myneuronews June 3, 2025

by myneuronews June 3, 2025

Study overview This research investigates the phenomenon of spontaneous recovery from growth hormone deficiency (GHD) …

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Functional neurological disorders
Alterations in Cortical Microstructure, Morphology, and Intrinsic Local Function in Spiking Tissue in Patients With Focal Epilepsy

by myneuronews June 3, 2025

by myneuronews June 3, 2025

Cortical Microstructure Alterations Cortical microstructure alterations in individuals with focal epilepsy involve complex changes in …

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Traumatic brain injury
Abstracts of the 5th Annual Meeting of the Canadian Concussion Network/Reseau Canadien des Commotions (CCN-RCC)

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Study Overview The 5th Annual Meeting of the Canadian Concussion Network (CCN-RCC) gathered researchers, healthcare …

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Functional neurological disorders
Microglia-drive IRF8 upregulates complement pathway in Parkinson’s disease

by myneuronews June 2, 2025

by myneuronews June 2, 2025

Microglia and Parkinson’s Disease Microglia are the primary immune cells of the central nervous system, …

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Traumatic brain injury
Factors affecting mortality risk in pediatric head injuries in Africa: a meta-analysis

by myneuronews May 31, 2025

by myneuronews May 31, 2025

Overview of Pediatric Head Injuries in Africa Pediatric head injuries represent a significant public health …

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Headaches
Human Herpesvirus-6 Infectious Meningitis With Lymphadenitis in an Immunocompetent Adult

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Study Overview This research explored a case involving Human Herpesvirus-6 (HHV-6) leading to infectious meningitis …

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Carotid and Vertebral Artery Dissections
Epidemiology and Risk Factors Carotid and vertebral artery dissections are relatively uncommon vascular injuries characterized…
The CSF Levels of Mitochondrial Phosphoenolpyruvate Carboxykinase 2 as a Novel Biomarker in Alzheimer’s Disease
Study Overview The research focuses on the role of mitochondrial phosphoenolpyruvate carboxykinase 2 (PEPCK-M) levels…
Complex dissociation following maternal suicide attempt in a 17-year-old female: a case report
Case Presentation In this case, we explore a 17-year-old female who was brought to the…
Motor stereotypies, Dhat syndrome, and gaming disorder: A masquerading presentation of Wilson’s disease
Wilson’s Disease Overview Wilson’s disease is a rare genetic disorder that results in excessive copper…
Clinical Outcomes in the Patient With Traumatic Brain Injury and Comorbid Obesity: A Scoping Review
Clinical Outcomes in Traumatic Brain Injury Traumatic brain injury (TBI) represents a significant challenge in…

Clinical Outcomes in the Patient With Traumatic Brain Injury and Comorbid Obesity: A Scoping Review
Very few studies exist examining the effects of mild traumatic brain injury (mTBI) in patients with obesity, which is notable given that mTBI represents ~80% of all recorded TBIs. Given that approximately 40% of US adults have an obese body mass index (with predictions that this proportion will continue to increase), it would be prudent […]
Reaching Underserved Communities in Partnership with Outreach Athletic Trainers
INTRODUCTION: Outreach athletic trainers (ATs) are a novel community-clinical linkage who connect high school students and family medicine practices. Our study quantitatively explored the relationship between students and ATs.
Targeted complement inhibition ameliorates the pathological and cognitive outcomes in repetitive mild closed head injury
Repeated mild closed head injury (rmCHI) is a significant public health concern, and this type of repetitive injury is garnering increasing attention, not least because of its increasing incidence in sports. The underlying neuroimmune mechanisms secondary to trauma that link rmCHI to cognitive impairment remain to be elucidated, and the contribution of the complement system […]
MSC-Exosomes alleviate cognitive impairment after mild traumatic brain injury by inhibiting ferroptosis via PI3K/AKT/mTOR-mediated upregulation of GPX4
Mild traumatic brain injury (mTBI) is a prevalent condition accounting for over 70% of all traumatic brain injury (TBI) cases, and it is a major cause of posttraumatic cognitive impairment. Ferroptosis, a form of regulated cell death characterized by iron-dependent lipid peroxidation, has been implicated in the pathophysiology of mTBI. However, its precise role in […]
2Innate immune signaling mediates differential acute and long-term outcomes of repeated vs. single TBI in Drosophila
Traumatic brain injuries (TBIs) are a global source of hospitalization, long-term disability, and death. However, age, sex, and other demographics differ widely among patients and the variable characteristics of TBIs further obscure injury outcomes. Here, we used Drosophila melanogaster to assess the effects of mild, repeated TBI (multi-day, MD) compared to single, severe TBI (single-day, […]