Tag:

clinical management

Traumatic brain injury
Clinical Evaluation of the TBI Assay in a Representative Emergency Department Cohort

by myneuronews October 22, 2025

by myneuronews October 22, 2025

Study Overview The evaluation centered on the efficacy and reliability of the TBI Assay within …

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Traumatic brain injury
Pre-injury sleep disturbance as a moderator of cognitive functioning in children and adolescents with mild traumatic brain injury

by myneuronews October 22, 2025

by myneuronews October 22, 2025

Study Overview The research investigates the complex interplay between pre-injury sleep disturbances and cognitive outcomes …

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Headaches
First detection of echovirus 18 associated with aseptic meningitis in a child in Niger Republic, 2024: a case report

by myneuronews October 22, 2025

by myneuronews October 22, 2025

Background of Echovirus 18 Echovirus 18, part of the Enterovirus genus within the Picornaviridae family, …

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Traumatic brain injury
Diagnostic and prognostic role of serum/plasma and CSF amyloid beta peptide levels in traumatic brain injury: a systematic review and meta-analysis

by myneuronews October 11, 2025

by myneuronews October 11, 2025

Background and Rationale Traumatic brain injury (TBI) represents a significant public health issue, with far-reaching …

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Traumatic brain injury
CONCUSS randomised clinical trial of vergence/accommodative therapy for concussion-related symptomatic convergence insufficiency

by myneuronews October 1, 2025

by myneuronews October 1, 2025

Study Overview The CONCUSS trial was designed as a randomized clinical study to evaluate the …

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Traumatic brain injury
Application of Machine Learning in the Diagnosis and Prognosis of Mild Traumatic Brain Injury Using Diffusion Tensor Imaging: A Systematic Review

by myneuronews September 30, 2025

by myneuronews September 30, 2025

Study Overview The exploration of mild traumatic brain injury (mTBI) has gained significant traction in …

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Traumatic brain injury
Sex-differences in catecholamine transporter expression in the rodent prefrontal cortex following repetitive mild traumatic brain injury and methylphenidate treatment

by myneuronews September 22, 2025

by myneuronews September 22, 2025

Study Overview The research investigates the impact of repetitive mild traumatic brain injury (mTBI) on …

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Traumatic brain injury
Concussion Disrupts Sleep in Adolescents: A Systematic Review and Meta-Analysis

by myneuronews September 22, 2025

by myneuronews September 22, 2025

Study Overview The objective of this systematic review and meta-analysis was to explore the impact …

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Traumatic brain injury
Spautin-1 alleviates depression-like behaviors in mice after traumatic brain injury by inhibiting MMP3 expression in microglia in the Hippocampal CA1 region

by myneuronews September 12, 2025

by myneuronews September 12, 2025

Study Overview The research in question investigates the effects of Spautin-1, a compound known for …

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Traumatic brain injury
Quantifying Longitudinal Microstructural Changes in Mild Traumatic Brain Injury Patients with Mean Apparent Propagator MRI

by myneuronews September 10, 2025

by myneuronews September 10, 2025

Study Overview This study investigates the microstructural changes in brain tissue associated with mild traumatic …

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Head injuries in intimate partner violence: cognitive, motor, and psychiatric symptoms
CONCLUSION: IPV groups reported more health issues than controls, and those with IPV-HI had the greatest rates of general health, cognitive, psychiatric, and neurobehavioral difficulties. These findings provide novel insight into IPV and IPV-related head injury outcomes.
Predictors of two consecutive knockout losses in ultimate fighting championship athletes
CONCLUSIONS: Among UFC athletes during this 8-year period, 23% sustained two knockout losses in a row. Predictors of two consecutive knockouts were older age, male sex, heavier weight class, and prior KO history, with prior KO history the only independent predictor. Recognizing prior knockout exposure as a key risk factor may help coaches and sports […]
The exercise and concussion health study (TECHS): Pilot and feasibility protocol
Mild traumatic brain injury (mTBI) is a prevalent neurological condition, affecting millions worldwide, and frequently resulting in persistent cognitive impairment that significantly impacts daily functioning. Current clinical management and recommendations lack evidence based therapeutic interventions, with treatment approaches limited to symptom monitoring and activity modification. Non-pharmaceutical interventions are needed to promote cognitive recovery and mitigate […]
Investigating associations between serum inflammatory cytokines at the time of second mild traumatic brain injury with acute neurological signs, axonal injury and behavioural outcomes in male Sprague-Dawley rats
Mild traumatic brain injury is a risk factor to sustaining future mild traumatic brain injuries and increased symptom severity and duration following a second mild traumatic brain injury. Inflammation during neurobiological recovery is hypothesized to influence susceptibility to poorer outcomes after repetitive mild traumatic brain injury. Here, we investigated whether the inflammatory response during neurobiological […]
Quantifying Mechanical Strain-Induced Membrane Damage in Early Neuronal Cells Using an In Vitro Traumatic Brain Injury Model
This protocol describes a reproducible workflow for modeling in vitro impact-induced traumatic brain injury (TBI) using a mechanical stretch system applied to differentiated SH-SY5Y human neuroblastoma cells cultured on polydimethylsiloxane (PDMS) substrates. The protocol integrates three primary components: (1) fabrication and surface modification of deformable PDMS chambers to support cellular adhesion, (2) partial differentiation of […]