Tag:

clinical signs

Functional neurological disorders
Clinical diagnosis and communication in functional neurological disorders: a survey among Italian neurologists

by myneuronews July 29, 2025

by myneuronews July 29, 2025

Understanding Functional Neurological Disorders Functional Neurological Disorders (FND) represent a group of conditions where patients …

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Functional neurological disorders
Childhood-Onset Neurodegeneration With Progressive Microcephaly (CONPM) due to a DTYMK Homozygous Pathogenic Variant: Outlining the Phenotype of an Ultra-Rare Disease

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Clinical Features of CONPM Childhood-Onset Neurodegeneration With Progressive Microcephaly (CONPM) is a rare genetic condition …

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Traumatic brain injury
Bedside Ultrasonographic Measurement of Optic Nerve Sheath Diameter for Assessing Increased Intracranial Pressure: An Observational Study

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Study Overview The research explored the feasibility and effectiveness of utilizing bedside ultrasonography to measure …

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Headaches
Comparing patient-reported symptoms and structured clinician documentation in electronic health records

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Symptom Reporting Comparisons Research into the differences between symptoms reported by patients and those documented …

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Traumatic brain injury
Bedside Ultrasonographic Measurement of Optic Nerve Sheath Diameter for Assessing Increased Intracranial Pressure: An Observational Study

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Study Overview The study investigated the effectiveness of bedside ultrasonography in measuring the diameter of …

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Dementia
Creutzfeldt-Jakob Disease in South Texas: A Case Series of Three Hispanic Patients

by myneuronews July 11, 2025

by myneuronews July 11, 2025

Study Overview This study examines a rare and debilitating neurodegenerative disorder, Creutzfeldt-Jakob Disease (CJD), as …

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Traumatic brain injury
Neurobiomarkers for Traumatic Brain Injury: Comparison of Serum Values Within 24 Hours of Injury With Glasgow Coma Scale (GCS) Scores in a Prospective Cohort Trial

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Neurobiomarkers in Traumatic Brain Injury Neurobiomarkers represent measurable indicators located in the body, which provide …

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Traumatic brain injury
Adaptive trial for the treatment of depressive symptoms associated with concussion using accelerated intermittent theta burst stimulation (ADEPT): rationale, design and methods

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Study Overview The ADEPT trial is designed to investigate the effectiveness of accelerated intermittent theta …

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Functional neurological disorders
Dynamic electro-clinical features in Guanidinoacetate N-methyltransferase deficiency: A familial case series

by myneuronews June 21, 2025

by myneuronews June 21, 2025

Clinical Presentation and Genetic Findings The study highlights the varied clinical presentations associated with Guanidinoacetate …

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Traumatic brain injury
Impact of anticoagulant therapy on delayed intracranial haemorrhage after traumatic brain injury: A study on the role of repeat CT scans and extended observation

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Background and Rationale Anticoagulant therapy is widely used in clinical practice to prevent thromboembolic events, …

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Cerebral Amyloid Angiopathy-Related Inflammation: Clinical Characteristics and Treatment Experience
Clinical Characteristics Cerebral Amyloid Angiopathy-Related Inflammation (CAA-RI) manifests through a variety of clinical symptoms that…
Collaborative Community Support for People Impacted by Dementia: A Social Return on Investment Analysis
Study Overview This research focuses on understanding the impact of a community-based support program designed…
A cognitive energy crisis: A systematic review & meta-analysis of effective interventions for pediatric cognitive fatigue post-acquired brain injury
Cognitive Fatigue in Pediatric Populations Cognitive fatigue is a significant concern in pediatric populations, particularly…
Investigating the Role of Gut-Derived Neurotoxin TMAO in PTSD Risk Following Traumatic Brain Injury
Study Overview This research investigates the connection between gut-derived neurotoxin trimethylamine N-oxide (TMAO) and the…
ENIGMA’s advanced guide for parcellation error identification (EAGLE-I): An implementation in the context of brain lesions
Study Overview The study focuses on enhancing the accuracy of brain lesion parcellation, a crucial…

Substrate-selective COX-2 inhibition by IMMA attenuates posttraumatic headache via endocannabinoid modulation and neuroinflammatory suppression
CONCLUSION: IMMA effectively attenuates neuroinflammation and pain hypersensitivity in the acute phase of PTH through a distinct mechanism that preserves endocannabinoid tone without suppressing physiological prostaglandins. While these results highlight its promise as a novel therapeutic strategy, further studies are warranted to determine its efficacy during the chronic phase of PTH and across anatomically targeted […]
Sensory integration processes characterize concussed athletes with balance deficits
Impaired postural control constitutes a major symptom after mild traumatic brain injuries (mTBI/sport-related concussions (SRC)). In order to uphold cognition and behavior during pathological situations, individuals may be characterized by neuronal upregulation. Because postural control necessitates the integration of sensory information within somatosensory (/parietal) cortices, we investigated the hypothesis that athletes with ongoing symptoms after […]
Intensive exposure therapy for individuals with persistent concussion symptoms following concussion: a replicated single-case experimental design (SCED) study
CONCLUSIONS: The findings of this study further confirmed the efficacy for this intensive exposure therapy for PCS, adding further evidence for exposure therapy in this patient population. Replication in other samples is needed.
Methods of humane killing of laboratory fish: FELASA Working Group recommendations
As commissioned by the Federation of European Laboratory Animal Science Associations, these working group recommendations define the requirements to achieve the humane killing of fish, compare methods of killing, recommend methods of killing depending on context, and detail protocols leading to good practice. With a review of current practices in a fish laboratory and available […]
A cognitive energy crisis: A systematic review & meta-analysis of effective interventions for pediatric cognitive fatigue post-acquired brain injury
Acquired Brain Injuries (ABIs) cause long-term disruption to young individuals' development. Persistent cognitive fatigue is a commonly reported sequela following pediatric ABI. Currently, there are no evidence-based interventions targeting cognitive fatigue post-ABI amongst pediatric patients. The current systematic review and meta-analysis aimed to review research on the efficacy of pharmacological and non-pharmacological interventions for cognitive […]