Tag:

clinical signs

Functional neurological disorders
Childhood-Onset Neurodegeneration With Progressive Microcephaly (CONPM) due to a DTYMK Homozygous Pathogenic Variant: Outlining the Phenotype of an Ultra-Rare Disease

by myneuronews July 23, 2025

by myneuronews July 23, 2025

Clinical Features of CONPM Childhood-Onset Neurodegeneration With Progressive Microcephaly (CONPM) is a rare genetic condition …

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Traumatic brain injury
Bedside Ultrasonographic Measurement of Optic Nerve Sheath Diameter for Assessing Increased Intracranial Pressure: An Observational Study

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Study Overview The research explored the feasibility and effectiveness of utilizing bedside ultrasonography to measure …

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Headaches
Comparing patient-reported symptoms and structured clinician documentation in electronic health records

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Symptom Reporting Comparisons Research into the differences between symptoms reported by patients and those documented …

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Traumatic brain injury
Bedside Ultrasonographic Measurement of Optic Nerve Sheath Diameter for Assessing Increased Intracranial Pressure: An Observational Study

by myneuronews July 18, 2025

by myneuronews July 18, 2025

Study Overview The study investigated the effectiveness of bedside ultrasonography in measuring the diameter of …

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Dementia
Creutzfeldt-Jakob Disease in South Texas: A Case Series of Three Hispanic Patients

by myneuronews July 11, 2025

by myneuronews July 11, 2025

Study Overview This study examines a rare and debilitating neurodegenerative disorder, Creutzfeldt-Jakob Disease (CJD), as …

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Traumatic brain injury
Neurobiomarkers for Traumatic Brain Injury: Comparison of Serum Values Within 24 Hours of Injury With Glasgow Coma Scale (GCS) Scores in a Prospective Cohort Trial

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Neurobiomarkers in Traumatic Brain Injury Neurobiomarkers represent measurable indicators located in the body, which provide …

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Traumatic brain injury
Adaptive trial for the treatment of depressive symptoms associated with concussion using accelerated intermittent theta burst stimulation (ADEPT): rationale, design and methods

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Study Overview The ADEPT trial is designed to investigate the effectiveness of accelerated intermittent theta …

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Functional neurological disorders
Dynamic electro-clinical features in Guanidinoacetate N-methyltransferase deficiency: A familial case series

by myneuronews June 21, 2025

by myneuronews June 21, 2025

Clinical Presentation and Genetic Findings The study highlights the varied clinical presentations associated with Guanidinoacetate …

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Traumatic brain injury
Impact of anticoagulant therapy on delayed intracranial haemorrhage after traumatic brain injury: A study on the role of repeat CT scans and extended observation

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Background and Rationale Anticoagulant therapy is widely used in clinical practice to prevent thromboembolic events, …

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Functional neurological disorders
Diagnostic Challenges in Creutzfeldt-Jakob Disease: A Case Report of an Atypical Presentation

by myneuronews June 17, 2025

by myneuronews June 17, 2025

Atypical Clinical Presentation Creutzfeldt-Jakob Disease (CJD), a rare and progressively fatal neurodegenerative disorder, is primarily …

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Interventional Treatment Strategies for Headache and Facial Pain
Interventional Techniques and Approaches Interventional techniques for managing headache and facial pain involve various procedures…
Systematic post-translational modification genome wide identifies therapeutic targets for Alzheimer’s disease: evidence from multi-cohort analysis
Identifying Therapeutic Targets In recent years, identifying therapeutic targets for Alzheimer’s disease (AD) has gained…
Functional Connectivity Gradients Reveal Altered Hierarchical Cortical Organization in Functional Neurological Disorder
Functional Connectivity Analysis Functional connectivity analysis has emerged as a pivotal method for understanding how…
An Intervention to Improve Emotion Regulation in Individuals With Traumatic Brain Injury: A Randomized Controlled Trial
Study Overview This research focused on assessing the effectiveness of a targeted intervention aimed at…
Evolution of Axonal Injury in the Closed Head Impact Model of Engineered Rotational Acceleration in Adult Ferrets
Study Overview This research examines the impact of engineered rotational acceleration on axonal injury in…

SaVeBRAIN.Kids-study protocol for a cluster-randomized stepped-wedge trial to reduce hospitalizations for mild traumatic brain injury in children in Germany
BACKGROUND: Traumatic brain injury (TBI) is one of the most important pediatric conditions worldwide. In Germany, hospitalization rates for mild TBI drastically exceed hospitalization rates from similar healthcare systems.
An Intervention to Improve Emotion Regulation in Individuals With Traumatic Brain Injury: A Randomized Controlled Trial
CONCLUSIONS: Evidence supports the efficacy of Online EmReg to improve ER following TBI.
Evolution of Axonal Injury in the Closed Head Impact Model of Engineered Rotational Acceleration in Adult Ferrets
Concussion-related symptoms, such as impaired balance, slower processing speed, attention deficits, memory dysfunction, and irritability, are thought to result from diffuse axonal injury (DAI), characterized by selective damage to white matter axons. Axons subjected to this mechanical stretch injury exhibit diverse pathological changes, including disruption of axonal transport, neurofilament compaction and degradation, myelin sheath disruption, […]
Brain Injury Within Intimate Partner Violence: What Are the Cognitive Effects?
Intimate partner violence (IPV) is a worldwide health concern with devastating implications for physical, mental, and cognitive health. IPV-associated brain injuries (IPV-BIs) induced through impacts to the head (e.g., mild traumatic brain injury [mTBI]) and non-fatal strangulation (NFS; i.e., a hypoxic-ischemic injury) have long been overlooked among IPV victim-survivors. Identifying their presence and consequences is […]
Specific alterations of reactive species interactome markers reflect recovery after mild traumatic brain injury
Recovery from mild traumatic brain injury (mTBI) is believed to be mediated by the secondary injury response with oxidative stress (OS) playing a central role. Previous studies have largely examined isolated OS markers, yielding inconsistent results. This study adopts a more integrated approach by investigating various components of the reactive species interactome (RSI), a conceptual […]