Tag:

clinical symptoms

Dementia
Identification of expanded and interrupted ATXN2 repeat expansions in Parkinson’s disease and Lewy Body Dementia cohorts

by myneuronews November 27, 2025

by myneuronews November 27, 2025

Study Overview This research investigates the presence and significance of expanded and interrupted repeat expansions …

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Functional neurological disorders
Epidemiology of functional neurological disorder – The clinical spectrum

by myneuronews November 25, 2025

by myneuronews November 25, 2025

Epidemiological Trends in Functional Neurological Disorder The epidemiology of functional neurological disorder (FND) reveals several …

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Headaches
Efficacy and safety of mirikizumab in paediatric participants with moderately-to-severely active ulcerative colitis (SHINE-1): a multicentre, open-label, non-randomised phase 2 trial

by myneuronews November 21, 2025

by myneuronews November 21, 2025

Study Overview The study aimed to evaluate the effectiveness and safety of mirikizumab, a monoclonal …

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Functional neurological disorders
Prepulse inhibition of the blink reflex in functional neurological disorder and fibromyalgia

by myneuronews November 21, 2025

by myneuronews November 21, 2025

Mechanisms of Prepulse Inhibition Prepulse inhibition (PPI) is a phenomenon where a weak stimulus (the …

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Functional neurological disorders
Motor stereotypies, Dhat syndrome, and gaming disorder: A masquerading presentation of Wilson’s disease

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Clinical Presentation of Wilson’s Disease Wilson’s disease is a genetic disorder characterized by abnormal copper …

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Functional neurological disorders
Complex dissociation following maternal suicide attempt in a 17-year-old female: a case report

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Clinical Presentation The case study centers around a 17-year-old female who experienced complex dissociation following …

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Functional neurological disorders
Complex dissociation following maternal suicide attempt in a 17-year-old female: a case report

by myneuronews November 19, 2025

by myneuronews November 19, 2025

Case Presentation In this case, we explore a 17-year-old female who was brought to the …

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Functional neurological disorders
Treatments for Functional Neurological Disorder: A Practical Guide for Program Development

by myneuronews November 17, 2025

by myneuronews November 17, 2025

Treatment Approaches for FND Treatment for Functional Neurological Disorder (FND) requires a nuanced approach that …

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Traumatic brain injury
Metabolomics of cerebrospinal fluid following traumatic brain injury: Exploration of biomarkers for secondary injuries and severity

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Biomarkers in cerebrospinal fluid analysis Cerebrospinal fluid (CSF) serves as a crucial medium for assessing …

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Functional neurological disorders
Multisite, Multiancestry Genome-Wide Association Study Meta-Analysis of Functional Seizure Disorder in a Hospital Sample of 675,680 Patients

by myneuronews November 14, 2025

by myneuronews November 14, 2025

Study Design and Population The study utilized a robust multisite, multiancestry design, involving a comprehensive …

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Herpes simplex virus associated rhomboencephalitis mimicking demyelination: a case report
Study Overview This case report focuses on a unique instance of rhomboencephalitis, an inflammation of…
Assessing the health-related quality of life in informal caregivers of Alzheimer’s Disease: evidence from Malaysia
Health-Related Quality of Life in Caregivers The health-related quality of life (HRQoL) among informal caregivers…
Using Genetics to Shed Light on the Scientific Gray Zone of Functional Seizures
Genetic Factors in Functional Seizures Recent studies have begun to uncover the genetic underpinnings that…
2025 guideline update to acute treatment of migraine for adults in the emergency department: The American Headache Society evidence assessment of parenteral pharmacotherapies
Study Overview This comprehensive review focuses on the advances in the management of acute migraine…
Knee Biomechanics in Individuals With a Recent Concussion During Jump-Landing Tasks
Background and Rationale The relationship between concussions and subsequent physical performance, particularly in biomechanical tasks,…

MRI investigation of orientation-dependent changes in microstructure and function in a mouse model of mild traumatic brain injury
While neuroimaging studies have revealed notable white matter damage following mild traumatic brain injury (mTBI), the specific tracts and brain regions affected vary widely across studies. Here, we explored whether the spatial orientation of white matter tracts influences susceptibility to repeated mTBI, predicting that tracts oriented orthogonal to the axis of rotation of the head […]
Impulse Dyscontrol Symptoms Are Related to Amyloid Beta in Patients With Subjective Cognitive Decline and Mild Cognitive Impairment
CONCLUSION: The study identified a significant correlation between domain C of the MBI-C and CSF beta-amyloid peptide analysing Brazilian patients with SCD and MCI. The results reinforce the hypothesis of the relationship between impulsivity symptoms and amyloid pathology. Further studies involving the correlations between MBI and neuropsychiatric symptoms with AD CSF biomarkers are necessary.
2025 guideline update to acute treatment of migraine for adults in the emergency department: The American Headache Society evidence assessment of parenteral pharmacotherapies
CONCLUSIONS: Prochlorperazine IV and GONB must be offered to eligible adults presenting to the ED with a migraine attack for treatment of headache requiring parenteral therapy (level A - must offer) in those without contraindications, while hydromorphone IV must not be offered (level A - must not offer). Treatments that should be offered when appropriate […]
Knee Biomechanics in Individuals With a Recent Concussion During Jump-Landing Tasks
CONCLUSIONS: The concussion history group demonstrated similar knee biomechanical profiles to the healthy reference group during landing even with added cognitive demands in jump-landing tasks. Elevated lower extremity musculoskeletal injury risk postconcussion may not be detectable through jump-landing biomechanics.
Effect of anticoagulation on isolated traumatic brain injury mortality using TQIP database: a propensity score analysis stratified by head injury severity
INTRODUCTION: The impact of anticoagulation (AC) on traumatic brain injury (TBI) outcomes remains varied in the literature. Previous studies often relied on single-center data, small sample sizes, or lacked adjustments for key confounding variables. This study used the population-based Trauma Quality Improvement Program (TQIP) database to analyze the effect of AC on isolated TBI mortality, […]