Tag:

clinical symptoms

Functional neurological disorders
A 2025 update on treatment strategies for the Alzheimer’s disease spectrum

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Current Treatment Approaches The treatment landscape for Alzheimer’s disease has evolved considerably, reflecting a multifaceted …

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Headaches
Human Herpesvirus-6 Infectious Meningitis With Lymphadenitis in an Immunocompetent Adult

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Study Overview This research explored a case involving Human Herpesvirus-6 (HHV-6) leading to infectious meningitis …

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Traumatic brain injury
Post-Concussion Changes in the Functional Brain Connectome Relative to Pre-Injury Baseline: A Prospective Observational Study

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Study Overview This research investigates alterations in the functional connectivity of the brain before and …

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Functional neurological disorders
Advances in Diagnostic Approaches for Alzheimer’s Disease: From Biomarkers to Deep Learning Technology

by myneuronews May 30, 2025

by myneuronews May 30, 2025

Advancements in Biomarker Identification Recent developments in the field of Alzheimer’s disease diagnostics have centered …

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Functional neurological disorders
Phosphoribosylformylglycinamidine Synthase (PFAS) Deficiency: Clinical, Genetic and Metabolic Characterisation of a Novel Defect in Purine de Novo Synthesis

by myneuronews May 27, 2025

by myneuronews May 27, 2025

Clinical Presentation and Symptoms Phosphoribosylformylglycinamidine synthase (PFAS) deficiency presents a complex array of clinical symptoms …

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Functional neurological disorders
Immune inflammatory regulation in Anti-NMDAR encephalitis: insights from transcriptome analysis

by myneuronews May 26, 2025

by myneuronews May 26, 2025

Immune Mechanisms in Anti-NMDAR Encephalitis Anti-NMDAR encephalitis is characterized by the presence of antibodies that …

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Functional neurological disorders
Comprehensive Neuropsychological Assessment of Confirmed Xeroderma Pigmentosum a Variant with Neurological Manifestations: Case Report

by myneuronews May 25, 2025

by myneuronews May 25, 2025

Clinical Presentation and Symptoms The case of a patient with xeroderma pigmentosum (XP) confirmed the …

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Functional neurological disorders
Penetrance of neurodevelopmental copy number variants is associated with variations in cortical morphology

by myneuronews May 25, 2025

by myneuronews May 25, 2025

Neurodevelopmental Variants and Penetrance Neurodevelopmental copy number variants (CNVs) represent significant alterations in an individual’s …

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Functional neurological disorders
Biochemical investigation of pathogenic missense mutations of human 4-amino butyrate aminotransferase towards the understanding of the molecular pathogenesis of GABA transaminase deficiency

by myneuronews May 25, 2025

by myneuronews May 25, 2025

Biochemical Characterization of Mutant 4-Aminobutyrate Aminotransferase In this detailed study, researchers focused on the biochemical …

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Functional neurological disorders
Developing a disease-specific accessible transcriptional signature as a biomarker for ataxia with oculomotor apraxia type 2

by myneuronews May 24, 2025

by myneuronews May 24, 2025

Background of Ataxia with Oculomotor Apraxia Type 2 Ataxia with oculomotor apraxia type 2 (AOA2) …

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Unsophisticated AI coaching does not improve performance on symptom and performance validity tests in a Romanian sample of experimental feigners
The present study aimed to investigate the ability of symptom and performance validity indicators to detect experimental feigning with symptom-coaching vs. AI assistance. Fifty-nine undergraduates and community members (45 females, M(Age)=22.6, SD(Age)=2.1; M(Education)=14.5, SD(Education)=1.4) were randomized into three experimental groups: controls (n = 20), symptom-coached feigners (n = 20), and AI-coached feigners (n = 19). […]
Factors affecting mortality risk in pediatric head injuries in Africa: a meta-analysis
CONCLUSION: Our study emphasizes RTA and seizures at presentation as key risk factors for mortality. We recommend early preventive measures, such as infrastructure improvements, to enhance road safety and reduce mortality.
Nonsteroid Anti-Inflammatory Drug Use in Female Elite Ice Hockey Players With and Without Previous Concussions and Musculoskeletal Injuries
Ice hockey is a high-intensity sport with high rates of concussions and musculoskeletal injuries. To manage pain, players may (over) use nonsteroid anti-inflammatory drugs (NSAIDs) which can have adverse health effects. In 2022, the Swedish Women's Elite League (SDHL) became the first women's league to introduce body checking, potentially increasing injury risks and NSAID use. […]
Single-nucleus and spatial signatures of the brainstem in normal brain and mild traumatic brain injury in male mice
The mammalian brainstem is particularly vulnerable to mild traumatic brain injury (mTBI), which is associated with prolonged autonomic dysfunction and coma. The spatial cellular connections within the brainstem or the mechanisms underlying its response to injury have been underestimated. Here, we performed single-nucleus RNA sequencing with spatial transcriptome sequencing in both normal and mTBI brainstems […]
Post-Concussion Changes in the Functional Brain Connectome Relative to Pre-Injury Baseline: A Prospective Observational Study
There is growing concern about the long-term health consequences of concussion, stemming from its high incidence and evidence of post-injury sequelae. This has raised critical questions about clinical assessments of concussion recovery, and whether brain function has fully recovered at medical clearance. The major knowledge gap is only partly addressed by conventional cross-sectional neuroimaging studies, […]