Tag:

cognitive impairment

Functional neurological disorders
Gene replacement therapy to restore polyamine metabolism in a Snyder-Robinson syndrome mouse model

by myneuronews May 17, 2025

by myneuronews May 17, 2025

Restoration of Polyamine Metabolism The restoration of polyamine metabolism represents a pivotal intervention in the …

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Functional neurological disorders
Unveiling diverse clinical symptom patterns and neural activity profiles in major depressive disorder subtypes

by myneuronews May 16, 2025

by myneuronews May 16, 2025

Clinical Symptom Patterns in Major Depressive Disorder In the realm of mental health, Major Depressive …

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Dementia
Olfaction and Plasma Biomarkers of Alzheimer Disease and Neurodegeneration in the Atherosclerosis Risk in Communities Study

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Link Between Olfaction and Neurodegeneration The sense of smell, or olfaction, has been increasingly recognized …

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Functional neurological disorders
Revealing heterogeneity in mild cognitive impairment based on individualized structural covariance network

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Understanding Mild Cognitive Impairment Heterogeneity Mild cognitive impairment (MCI) is a clinical condition that marks …

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Traumatic brain injury
Sensory driven neurophysiological mechanisms of concussion: a parsimonious and falsifiable theory

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Overview of Neurophysiological Mechanisms Understanding the neurophysiological mechanisms underlying concussion involves delving into the complex …

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Functional neurological disorders
Association of APOC1 with cortical atrophy during conversion to Alzheimer’s disease

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Association of Apolipoprotein C1 and Cognitive Decline The relationship between apolipoprotein C1 (APOC1) and cognitive …

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Traumatic brain injury
Longitudinal assessment of post-concussion driving reaction time

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Background and Rationale Understanding the effects of concussive injuries on cognitive and motor skills is …

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Functional neurological disorders
Association of APOC1 with cortical atrophy during conversion to Alzheimer’s disease

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Association of Apoc1 with Alzheimer’s Disease Recent research has underscored the significance of the apolipoprotein …

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Functional neurological disorders
Research Progress on BDNF and Depression

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Understanding BDNF in Depression Brain-Derived Neurotrophic Factor (BDNF) is a crucial protein that supports the …

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Traumatic brain injury
Correction: Cerebral Haemodynamic Assessment Following Sport-related Concussion (Mild Traumatic Brain Injury) in Youth and Amateur Rugby Union Players

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Cerebral haemodynamics in concussion Cerebral haemodynamics refers to the dynamics of blood flow within the …

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Midlife plasma proteomic profiles indicate altered amyloid and tau processing in former elite rugby players
CONCLUSIONS: Ex-players showed distinctive plasma biomarker changes, more prominently in ex-forwards, possibly reflecting greater RHI exposure. Plasma KLK6, an endothelial serine protease, was reduced across the ex-player group, with potential diagnostic or prognostic utility in future. Reduced GFAP and SNAP25 in ex-forwards has an uncertain basis, while elevated p-tau-(181) more so than p-tau(217) points towards […]
A Guide to the Interpretation and Reliability of Annual Collegiate ImPACT Baselines by Sex
CONCLUSIONS: This study found sex differences on ImPACT performance, suggesting that sex-specific MDC values are needed to evaluate significant changes in ImPACT scores. Additionally, this study found several ImPACT subtest scores to be unreliable, suggesting only moderate to good scores be used in clinical evaluation.
<em>Taking Control of Your Functional Cognitive Symptoms: Workbook</em>-A Novel Intervention
CONCLUSIONS: This promising new multimodality behavioral health intervention can be considered to be in stage 1 (i.e., intervention generation, refinement, modification, adaptation, and pilot testing). Further pilot testing is being conducted and will need to be followed by traditional efficacy testing (in stage 2).
Hemodynamic Oscillations in Mild TBI During Postural Change: An fNIRS Pilot Study
We demonstrate that low-frequency oscillations (LFOs) in cerebral hemodynamics, measured by frequency-domain functional near-infrared spectroscopy (FD-fNIRS), reflect altered cerebral hemodynamic oscillations in mild traumatic brain injury (mTBI). In a pilot study of two mTBI and 13 healthy subjects undergoing head-of-bed positional changes, we analyzed total hemoglobin concentration (THC), oxyhemoglobin (HbO), and deoxyhemoglobin (Hb) dynamics using […]
Normative Data for Single- and Dual-Task Tandem Gait Performance in Collegiate Athletes
CONCLUSION: Our results provide robust normative data for single- and dual-task tandem gait stratified by relevant patient factors that can be immediately used by clinicians and future researchers. Future research should compare the use of individual baseline versus normative data for acute concussion tracking.