Tag:

cognitive impairment

Traumatic brain injury
Diffusion Tensor Image Analysis Along the Perivascular Space in Former Professional Athletes with Repetitive Mild Traumatic Brain Injury History

by myneuronews May 3, 2025

by myneuronews May 3, 2025

Study Overview This research focuses on the implications of repetitive mild traumatic brain injuries (mTBI) …

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Functional neurological disorders
Randomised controlled feasibility trial of online group acceptance and commitment therapy for functional cognitive disorder

by myneuronews May 2, 2025

by myneuronews May 2, 2025

Background and Objectives Functional Cognitive Disorder (FCD) stands at the intersection of cognitive function and …

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Dementia
Telehealth coaching in older adults, behavior change, and impacts of the COVID-19 pandemic: analyses from The Brain Health Champion Study

by myneuronews May 2, 2025

by myneuronews May 2, 2025

Telehealth Coaching Overview Telehealth coaching has emerged as a pivotal tool in promoting health and …

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Traumatic brain injury
Enhancing Sport-Related Concussion Return-to-Play Protocols for Non-Professional Athletes

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Background on Sport-Related Concussions Sport-related concussions are a form of mild traumatic brain injury that …

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Traumatic brain injury
Associations of Collegiate Football Career and Incident Concussion with Players’ Health: A Longitudinal Study from the CARE Consortium

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Background and Rationale In recent years, the growing concern surrounding sports-related concussions has prompted educators, …

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Dementia
Association of Alzheimer’s Disease and Related Dementias (ADRD) With Days at Home Among Medicare Beneficiaries After a Heart Failure Hospitalization

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Association With Days at Home The amount of time spent at home after a hospitalization …

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Traumatic brain injury
Effects of Subanesthetic Intravenous Ketamine Infusion on Stress Hormones and Synaptic Density in Rats with Mild Closed-Head Injury

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Effects of Ketamine on Stress Hormones Research on the impact of ketamine, particularly in its …

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Dementia
FOXG1 Improves Cognitive Function in Alzheimer’s Disease by Promoting Endogenous Neurogenesis

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Impact of FOXG1 on Neurogenesis The role of FOXG1 in neurogenesis is increasingly being recognized …

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Traumatic brain injury
The role of cardiovascular response as a predictor of neurologic disability in children with brain injury – a pilot study

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Background and Rationale The interaction between the cardiovascular system and the brain is complex and …

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Functional neurological disorders
Striato-cortical connectivity patterns predict clinical profiles in Huntington’s disease

by myneuronews April 25, 2025

by myneuronews April 25, 2025

Striato-Cortical Connectivity in Huntington’s Disease The study systematically examined the intricacies of striato-cortical connectivity in …

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Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus
Background/Objectives: A concussive head injury increases the likelihood of temporal lobe epilepsy through mechanisms that are not entirely understood. This study aimed to investigate how two key histopathological features shared by both TLE (temporal lobe epilepsy) and head injury-mossy fiber sprouting and hilar excitatory cell loss-contribute to the modulation of dentate gyrus excitability. Methods: A […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.