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    Overview of Classification Systems and Diagnostic Criteria for Traumatic Brain Injury Syndromes

    by Ioannis Mavroudis February 13, 2024
    by Ioannis Mavroudis February 13, 2024

    This article presents a comprehensive overview of the classification systems for traumatic brain injuries (TBI) …

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  • Vestibular migraine vs. migraine only: integrated transcriptome-clinical profiling reveals shared inflammation and divergent metabolic pathways for targeted therapy
    Study Overview This research investigates the similarities and differences between vestibular migraine and typical migraine…
  • Concurrent detection of cognitive impairment and amyloid positivity with a multimodal machine learning-enabled digital cognitive assessment
    Cognitive Impairment Detection Cognitive impairment represents a spectrum of conditions that affect an individual’s cognitive…
  • Diagnostic delay and associated clinical factors in a sample of South African patients with functional seizures
    Clinical Characteristics of Functional Seizures Functional seizures, also referred to as non-epileptic seizures, present a…
  • Differential DNA Methylation of the Brain-Derived Neurotrophic Factor Gene is Observed after Pediatric Traumatic Brain Injury Compared with Orthopedic Injury
    Study Overview This study investigates the changes in DNA methylation of the brain-derived neurotrophic factor…
  • Patterns, severity, and outcomes of traumatic brain injury in a regional referral hospital in Kenya: a retrospective cohort study
    Patterns of Traumatic Brain Injury Traumatic brain injury (TBI) is a significant public health challenge,…

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  • Patterns, severity, and outcomes of traumatic brain injury in a regional referral hospital in Kenya: a retrospective cohort study
    CONCLUSION: The study highlights the high burden of preventable TBI from RTAs and assaults in this setting. The high assault rate, low imaging access, and limited neurosurgical intervention capacity are major concerns. While the findings are limited to admitted patients and short-term outcomes, they underscore the urgent need for targeted road safety initiatives, improved access […]
  • Differential DNA Methylation of the Brain-Derived Neurotrophic Factor Gene is Observed after Pediatric Traumatic Brain Injury Compared with Orthopedic Injury
    Pediatric traumatic brain injury (TBI) triggers biological changes that may differ from those observed in non-brain injuries. Brain-derived neurotrophic factor (BDNF) DNA methylation (DNAm) may serve as a novel, dynamic biomarker of the brain's response and help identify TBI-specific epigenetic patterns relevant to later recovery. Therefore, the purpose of this study was to examine whether […]
  • Efficacy and safety of exosomes from Wharton's Jelly-derived mesenchymal stem cells in traumatic brain injury
    CONCLUSION: MSCdE therapy is safe and effective in improving motor function, cognition, and quality of life in TBI patients. Larger, controlled trials are needed to further validate these findings and optimize MSCdE therapy for TBI treatment.
  • Traumatic Brain Injury Across the Lifespan and in Conflict Zones
    Traumatic brain injury is increasingly recognized as a chronic, age-dependent and context-dependent neurological condition rather than being just a singular event. Its incidence, mechanisms, and outcomes may vary across the lifespan, with children, adults, and older adults exhibiting distinct clinical trajectories. These injuries can lead to long-term cognitive, behavioral, and psychosocial challenges that may only […]
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