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  • Traumatic brain injury

    Understanding White Matter Deformation: Insights into Brain Mechanics and Injury Prevention

    by Ioannis Mavroudis April 23, 2025
    by Ioannis Mavroudis April 23, 2025

    Introduction Traumatic brain injury (TBI) remains a significant public health concern, affecting millions globally each …

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  • Cognitive impairmentTraumatic brain injury

    Cognition After Traumatic Brain Injury: Rethinking Recovery, Complexity, and Hope

    by Ioannis Mavroudis April 13, 2025
    by Ioannis Mavroudis April 13, 2025

    Today, we’re delving into a topic that touches millions of lives but is still too …

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  • Diagnostic CriteriaTraumatic brain injury

    A Comparative Analysis of the ACRM Diagnostic Criteria and Mayo Classification System for Traumatic Brain Injury: Strengths, Limitations, and Clinical Accuracy

    by Ioannis Mavroudis March 14, 2025
    by Ioannis Mavroudis March 14, 2025

    Introduction Traumatic brain injuries (TBIs) remain a significant public health challenge, affecting millions worldwide each …

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  • Traumatic brain injury

    Oral Health and Concussions: An Overlooked Connection

    by Ioannis Mavroudis March 9, 2025
    by Ioannis Mavroudis March 9, 2025

    Introduction Concussions, or mild traumatic brain injuries (mTBI), have long been studied in the context …

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  • Chronic Traumatic EncephalopathyTraumatic brain injury

    Exploring the Complex Impact of Repeated Head Trauma in Contact Sports: Beyond CTE

    by Ioannis Mavroudis November 6, 2024
    by Ioannis Mavroudis November 6, 2024

    The connection between repeated head trauma and long-term health issues has gained significant attention in …

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  • Traumatic brain injury

    Charles Bonnet Syndrome (CBS) and Its Relationship with Concussion

    by Ioannis Mavroudis November 6, 2024
    by Ioannis Mavroudis November 6, 2024

    Charles Bonnet Syndrome (CBS) is a condition where individuals with significant vision loss experience visual …

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  • ResearchTraumatic brain injury

    The Impact of Tau Pathology in Chronic Traumatic Encephalopathy: Key Insights into Cognitive, Functional, and Neuropsychiatric Decline

    by Ioannis Mavroudis October 1, 2024
    by Ioannis Mavroudis October 1, 2024

    Recent research has shown significant connections between chronic traumatic encephalopathy (CTE) pathology and a variety …

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  • Traumatic brain injury

    The Role of the IMPACT Test in Concussion Screening and Treatment Planning

    by Ioannis Mavroudis September 28, 2024
    by Ioannis Mavroudis September 28, 2024

    Mild Traumatic Brain Injury (mTBI), commonly referred to as a concussion, has been a growing …

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  • Post traumatic headacheTraumatic brain injury

    Risk Factors for Post-Traumatic Headache (PTH)

    by Ioannis Mavroudis September 21, 2024
    by Ioannis Mavroudis September 21, 2024

    Post-traumatic headache (PTH) is a common and often debilitating condition that can develop after traumatic …

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  • Traumatic brain injury

    Is Post-Concussion Syndrome a Functional Disorder?

    by Ioannis Mavroudis September 14, 2024
    by Ioannis Mavroudis September 14, 2024

    Post-Concussion Syndrome (PCS) is a complex and often misunderstood condition that can arise after a …

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  • The effectiveness of physiotherapy for chronic headaches in patients with temporomandibular disorders: a systematic review
    Study Overview This systematic review focuses on the role of physiotherapy in treating chronic headaches…
  • Culturally Responsive Approaches to Brain Health and Dementia Education for American Indian, Alaska Native, and Native Hawaiian Communities
    Culturally Relevant Frameworks In addressing brain health and dementia education within American Indian, Alaska Native,…
  • Long-Term Follow-Up of Patients with Mass Social Media-Induced Illness Presenting with Functional Tic-like Behaviors
    Understanding Social Media’s Impact on Health Social media platforms have transformed the way individuals express…
  • Performance of GFAP and UCH-L1 compared to S100B in detecting intracranial injury: influence of age, hemolysis, neurodegenerative diseases, and extracranial fractures in a prospective cohort of over 1,000 patients
    Study Overview This study examined the efficacy of three biomarkers—GFAP (Glial Fibrillary Acidic Protein), UCH-L1…
  • Retired contact sports athletes with cognitive concerns: promoting lifelong brain health
    Understanding Cognitive Concerns in Retired Athletes Cognitive concerns in retired athletes, particularly those involved in…

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Research

  • Autologous bone marrow mononuclear cell administration for neurological sequelae after traumatic brain injury: a matched control study
    Neurological sequelae after traumatic brain injury impair motor and behavioural functions, imposing a heavy burden on patients and society. Traditional treatments show limited efficacy, highlighting the need for advanced therapies. This study evaluated the safety and efficacy of intrathecal administration of bone marrow mononuclear cells for treating these sequelae. A matched control clinical trial was […]
  • Concussion Classification in a Multicenter Patient Cohort: The Updated ACRM Diagnostic Criteria and Concordance With Physician Impression of Injury
    CONCLUSION: Use of the ACRM criteria clinically to determine if an injury qualifies as mTBI may be less susceptible to bias from ongoing symptom reporting than the physician impression of the injury.
  • Performance of GFAP and UCH-L1 compared to S100B in detecting intracranial injury: influence of age, hemolysis, neurodegenerative diseases, and extracranial fractures in a prospective cohort of over 1,000 patients
    CONCLUSIONS: S100B and the GFAP/UCH-L1 combination demonstrated very high sensitivities, close to 100 %, with specificities of approximately 30 % for the diagnosis of intracranial lesions. Age-adjusted thresholds improve specificity in older patients, supporting their clinical implementation. This study also provides the first evidence that hemolysis significantly elevates UCH-L1 concentrations from 400 mg/L of hemoglobin.
  • Retired contact sports athletes with cognitive concerns: promoting lifelong brain health
    There is widespread concern among former athletes about the link between head injury and dementia. Neurologists are increasingly assessing ex-contact sports athletes with cognitive and behavioural issues following repetitive head impacts and traumatic brain injury. Their assessment and management can be challenging due to the broad differential diagnosis, including psychiatric issues, trauma-related impairment and, in […]
  • Visible signs of possible concussion at the FIFA World Cup Qatar 2022: Independent review and inter-rater reliability
    CONCLUSIONS: Visible signs of concussion categorized as "red flags" were infrequent, resulting in uncertain reliability. The frequency and reliability of visible signs categorized as "yellow flags" and "other signs" varied, with the visible signs "clutching of the head" and "slow to get up" occurring so frequently that their utility for identifying possible concussion in football […]

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