Tag:

consciousness

Functional neurological disorders
Functional connectome integration observed after antispastic epidural cervical spinal cord stimulation in a patient with TBI-induced disorder of consciousness: a case report

by myneuronews July 7, 2025

by myneuronews July 7, 2025

Functional Connectome Changes The research presented valuable insights into the alterations in functional connectivity within …

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Functional neurological disorders
Functional connectome integration observed after antispastic epidural cervical spinal cord stimulation in a patient with TBI-induced disorder of consciousness: a case report

by myneuronews July 7, 2025

by myneuronews July 7, 2025

Functional Connectome Integration Recent advances in neuroimaging have enhanced our understanding of how different brain …

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Traumatic brain injury
Comparative analysis of plasma and salivary S100B as predictors of traumatic brain injury severity according to GCS and MAIS/head

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview The research investigates the efficacy of two biological markers, S100B protein levels in …

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Traumatic brain injury
Letter to the Editor: The importance of using validated case definitions in the epidemiology of concussion

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Importance of Validated Case Definitions Validated case definitions are crucial in the field of concussion …

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Traumatic brain injury
Comparative analysis of plasma and salivary S100B as predictors of traumatic brain injury severity according to GCS and MAIS/head

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview This research investigates the roles of plasma and salivary concentrations of S100B protein …

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Traumatic brain injury
Linked alterations in structure and autoimmunity biomarkers in remote mild-to-moderate TBI: A multi-modal brain imaging study

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Study Overview This research focused on the relationship between structural brain alterations and autoimmunity biomarkers …

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Traumatic brain injury
Plasma levels of biomarkers associated with vasodilation and neuroinflammation in pediatric patients with head trauma and their relationship with clinical characteristics of patients

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Biomarkers of Vasodilation and Neuroinflammation In recent studies focusing on pediatric patients with head trauma, …

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Traumatic brain injury
Neurobiomarkers for Traumatic Brain Injury: Comparison of Serum Values Within 24 Hours of Injury With Glasgow Coma Scale (GCS) Scores in a Prospective Cohort Trial

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Neurobiomarkers in Traumatic Brain Injury Neurobiomarkers represent measurable indicators located in the body, which provide …

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Traumatic brain injury
Correlation between bispectral index values and the Glasgow Coma Scale in traumatic brain injury patients: a prospective observational study

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Study Overview This study investigates the relationship between the bispectral index (BIS) and the Glasgow …

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Traumatic brain injury
Distinct clinical phenotypes and their neuroanatomic correlates in chronic traumatic brain injury

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Clinical Phenotypes In chronic traumatic brain injury (TBI), individuals often manifest a variety of clinical …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]