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decision-making

Traumatic brain injury
Early Venous Thromboembolism Prophylaxis in Brain Injury Guidelines 1 and Brain Injury Guidelines 2 Traumatic Brain Injury Patients: A 5-Year Analysis

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Background and Rationale Traumatic brain injury (TBI) represents a significant public health concern, with a …

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Traumatic brain injury
Clinical Characteristics and Outcomes of Pediatric Traumatic Brain Injury Patients in a Tertiary Regional Trauma Center in the Philippines

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Patient Demographics and Injury Mechanisms The study cohort comprised pediatric patients who sustained traumatic brain …

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Traumatic brain injury
On-Field Diagnosis and Management of Sports-Related Concussion in Pediatric Athletes

by myneuronews May 1, 2025

by myneuronews May 1, 2025

Understanding Concussion in Pediatric Athletes Concussions are a form of traumatic brain injury that occur …

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Functional neurological disorders
Mechanical stress contributes to ligamentum flavum hypertrophy by inducing local inflammation and myofibroblast transition in the innovative surgical rabbit model

by myneuronews April 30, 2025

by myneuronews April 30, 2025

Mechanisms of Ligamentum Flavum Hypertrophy The study delves into the complex changes that occur in …

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Traumatic brain injury
Early Pupil Abnormality Frequency Predicts Poor Outcomes and Enhances International Mission for Prognosis and Analysis of Clinical Trials in Traumatic Brain Injury (IMPACT) Model Prognostication in Traumatic Brain Injury

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Early Pupil Abnormality and Its Significance Pupil abnormalities, such as asymmetry or non-reactivity to light, …

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Traumatic brain injury
Single-Quantum Sodium MRI at 3T for the Separation of Mono- and Bi-T2 Sodium Signals

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Study Overview The study investigates an innovative approach to magnetic resonance imaging (MRI) aimed at …

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Functional neurological disorders
Silencer variants are key drivers of gene upregulation in Alzheimer’s disease

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Silencer Variants and Gene Regulation Recent advancements in genetic research have shed light on the …

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Functional neurological disorders
Regulation of chronic neuroinflammation through dietary herbal products

by myneuronews April 29, 2025

by myneuronews April 29, 2025

Role of Dietary Herbal Products in Neuroinflammation Dietary herbal products have garnered significant interest in …

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Functional neurological disorders
Imbalanced goal-directed and habitual control in individuals with internet gaming disorder

by myneuronews April 28, 2025

by myneuronews April 28, 2025

Understanding Internet Gaming Disorder Internet Gaming Disorder (IGD) has emerged as a significant concern in …

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Functional neurological disorders
MTHFR Gene Polymorphisms: A Single Gene with Wide-Ranging Clinical Implications-A Review

by myneuronews April 26, 2025

by myneuronews April 26, 2025

Clinical Significance of MTHFR Polymorphisms The MTHFR gene encodes the enzyme methylenetetrahydrofolate reductase, which plays …

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Real-world assessment of current migraine prophylaxis in Egypt: a multicenter national study
Study Overview The research conducted aimed to evaluate the existing practices regarding migraine prophylaxis across…
Treatment of Alzheimer’s disease from gut-brain interactions based on theory of “spleen deficiency leading to obstruction of nine orifices”
Understanding Gut-Brain Interactions The relationship between the gut and the brain is increasingly recognized as…
Update on functional vestibular and gait disorders
Current Understanding of Vestibular and Gait Disorders Vestibular and gait disorders have increasingly garnered attention…
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
Study Overview The investigation focused on the relationship between brain creatine concentrations and both sex…
Anti-Inflammatory Potential of Stearidonic Acid Ethanolamide in a Model of Mild Traumatic Brain Injury in Mice
Study Overview This study investigates the effects of stearidonic acid ethanolamide (SDA-EA) on inflammation following…

Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]
Injury-induced CTE-like pathology emerges in a human multicellular in vitro brain model and reveals mitochondrial and neurovascular regulation
Chronic traumatic encephalopathy (CTE) is a progressive neurodegenerative disease linked to repetitive mild head impacts, but no human-based experimental system exists to study injury-induced CTE-like pathology. Here, we establish a long-lived, human multicellular in vitro brain platform in which controlled mechanical injury induces key cellular features of CTE-like pathology. Injured cultures developed persistent tau phosphorylation, […]
Explosive shock wave exposure leads to age-accelerated motor and sensory decline in C. elegans
CONCLUSIONS: Defined shock wave exposure is sufficient to provoke long-term neuronal functional decline in C. elegans , accompanied by structural deterioration and premature neurodegeneration. This tractable model enables lifelong phenotyping and mechanistic dissection of how an acute shock wave insult progresses to chronic neuronal dysfunction, and provides a scalable platform for identifying molecular and pharmacological […]
Management of the paediatric patient with acute head trauma
Acute head trauma (AHT) leading to traumatic brain injury is an important cause of paediatric morbidity and mortality. Injury severity depends on the mechanism of trauma and age of the child. The vast majority of childhood AHT cases are mild, require no therapy, and leave no long-term sequelae. However, it is important to identify individuals […]
Brain creatine concentrations are associated with sex and symptom severity after concussion: a cross-sectional MR-spectroscopy investigation of adolescents with concussion
CONCLUSION: Post-concussion sex differences in creatine concentrations were detected, as higher creatine levels moderately correlated with patient-reported outcomes. Creatine may reflect altered energy dynamics in the brain. The absence of a non-injured control group limits determination of whether these differences are concussion-specific or reflective of baseline physiology.