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dementia

Functional neurological disorders
Human PrP E219K: a new and promising substrate for robust RT-QuIC amplification of human prions with potential for strain discrimination

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Overview of Prion Amplification Techniques Prion diseases are a group of progressive neurodegenerative disorders characterized …

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Functional neurological disorders
Insights into the Diagnosis, Treatment, and Management of Prion Diseases

by myneuronews July 10, 2025

by myneuronews July 10, 2025

Understanding Prion Diseases Prion diseases, a unique category of neurodegenerative disorders, are caused by misfolded …

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Dementia
Discrepancies between CSF biomarker and PET determinations of elevated brain amyloid and their prognostic significance

by myneuronews July 9, 2025

by myneuronews July 9, 2025

Study Overview The ongoing challenge of accurately diagnosing Alzheimer’s disease and other neurodegenerative conditions has …

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Dementia
Early outpatient clinical experience with xanomeline and trospium chloride for schizophrenia: a case report

by myneuronews July 7, 2025

by myneuronews July 7, 2025

Study Overview This article presents a detailed examination of the early outpatient clinical experiences involving …

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Dementia
Machine-learning based strategy identifies a robust protein biomarker panel for Alzheimer’s disease in cerebrospinal fluid

by myneuronews July 4, 2025

by myneuronews July 4, 2025

Study Overview The study examines the potential for machine-learning techniques to identify a reliable protein …

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Dementia
Metabolic changes in the one-carbon metabolism-related amino acids during etoposide-induced cellular senescence of neuronal cells

by myneuronews July 3, 2025

by myneuronews July 3, 2025

Metabolic Alterations in Neuronal Cells Metabolic changes in neuronal cells, particularly during cellular senescence, play …

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Functional neurological disorders
A dynamic prediction model for predicting the time at which patients with MCI progress to AD based on time-dependent covariates

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Dynamic Prediction Model Overview The study introduces a dynamic prediction model aimed at forecasting the …

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Traumatic brain injury
Brain health concerns in former rugby players: clinical and cognitive phenotypes

by myneuronews July 2, 2025

by myneuronews July 2, 2025

Context of Brain Health in Rugby The discussion around brain health in former rugby players …

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Dementia
Knowledge and attitudes towards Alzheimer’s disease among adult residents in Jiulongpo, Chongqing, China: A cross-sectional survey

by myneuronews June 30, 2025

by myneuronews June 30, 2025

Study Overview This research aimed to explore the awareness and perceptions regarding Alzheimer’s disease among …

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Dementia
Uncovering Putative Causal Non-Coding RNAs in Acute and Chronic Myeloid Leukemia: A Genome-Wide Mendelian Randomization Study

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The investigation aimed to explore the role of non-coding RNAs in the development …

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Controversies in the diagnosis of chronic inflammatory demyelinating polyneuropathy
Understanding Chronic Inflammatory Demyelinating Polyneuropathy Chronic Inflammatory Demyelinating Polyneuropathy (CIDP) is characterized by a progressive…
Interferon alfa and beta receptor confers resistance against Neospora caninum infection in mice
Study Overview This investigation focuses on the interaction between interferon-alfa and -beta receptors and their…
Advances and challenges in experimental models of posttraumatic epilepsy for therapeutic interventions
Experimental Models of Posttraumatic Epilepsy Research into posttraumatic epilepsy (PTE) has benefited significantly from various…
Anti-NMDA receptor encephalitis following SARS-CoV-2 infection in children
Study Overview The study investigates the neurological complications associated with anti-NMDA receptor encephalitis in pediatric…
Insights From a Mixed Methods Analysis of 3 Health Technologies Used in Patients With Parkinson Disease: Mixed Methods Study
Study Overview The research presented a comprehensive examination of three distinct health technologies utilized by…

Impact of knowledge and attitude on inappropriate post-concussion behaviors in competitive cyclists
CONCLUSIONS: An association was found between concussion knowledge and return to competition without a period of rest post-injury, as well as between attitude toward concussion and return to competition with symptoms. Therefore, these findings can contribute to concussion education among cyclists.
Living in the Shadows: My Personal Perspective With Mental Health After a Concussion
CONCLUSION: This narrative highlights the anxiety and depressive symptoms experienced after concussion. By incorporating mental health nurses within concussion care, mental health issues can be addressed in a timely and approriate manner.
Knockout of indoleamine 2,3-dioxygenase 1 gene expression improves depressive and anxiety-like phenotypes in a murine model of mild traumatic brain injury
CONCLUSION: IDO deficiency prevented mTBI-induced anxiety- and depressive-like behaviors and altered neurotrophic factor levels regionally. These findings implicate IDO in post-mTBI behavioral and neurotrophic responses, warranting further study of kynurenine pathway metabolites and downstream signaling to clarify the mechanism underlying the role of IDO in mTBI outcomes.
Interpreting Change in Sport Concussion Assessment Tool-5th Edition (SCAT5) Scores in National Rugby League Women's Premiership Players
CONCLUSION: SCAT5 scores had low to moderate test-retest reliability across a one-year period. Reliable change scores for the SCAT5 were developed in this study for use with professional women rugby league players. When evaluating post-injury SCAT5 scores, it can be helpful to consider both what the score means compared to normative reference values and compared […]
An update on paediatric traumatic brain injury in the emergency department: a narrative review
Traumatic brain injury (TBI) affects an estimated 330,000 to 500,000 children annually in England and Wales and represents a significant burden on healthcare systems. Presentations range from mild to severe, and each case presents unique challenges to the Emergency Department (ED) clinicians. Most paediatric TBIs are mild, and several validated clinical decision rules (CDRs) such […]