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dementia

Dementia
Uncovering Putative Causal Non-Coding RNAs in Acute and Chronic Myeloid Leukemia: A Genome-Wide Mendelian Randomization Study

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Study Overview The investigation aimed to explore the role of non-coding RNAs in the development …

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Traumatic brain injury
The national football league concussion settlement race-norming incident in context

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Concussion Settlement Overview The settlement resulting from the NFL’s concussion litigation, which emerged from concerns …

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Dementia
Depression exacerbates AD pathology through lactate-dependent activation of microglial Kv1.3 to promote Aβ-containing exosome spreading

by myneuronews June 27, 2025

by myneuronews June 27, 2025

Background and Rationale The intersection of depression and Alzheimer’s disease (AD) has garnered increasing attention …

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Dementia
Transplants of fresh and cryopreserved autologous adipose tissue improve reintegrative phenomena in newly formed muscle tissue in the reconstruction of muscle volume loss: A histological evaluation

by myneuronews June 25, 2025

by myneuronews June 25, 2025

Study Overview The research investigates the impact of transplanting both fresh and cryopreserved autologous adipose …

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Functional neurological disorders
Biotechnological Advances in L-DOPA Biosynthesis and Production

by myneuronews June 23, 2025

by myneuronews June 23, 2025

Advancements in L-DOPA Production Techniques The development of novel techniques for producing L-DOPA has seen …

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Functional neurological disorders
Regional structural differences in the brain related to high blood pressure

by myneuronews June 23, 2025

by myneuronews June 23, 2025

Regional Brain Changes Associated with Hypertension High blood pressure, or hypertension, has been shown to …

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Dementia
Stem Cell-Derived, Fully Differentiated Islets for Type 1 Diabetes

by myneuronews June 22, 2025

by myneuronews June 22, 2025

Background and Rationale The advancement of regenerative medicine has brought to the forefront the potential …

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Dementia
Identification of diagnostic DNA methylation markers in the blood of Japanese Alzheimer’s disease patients using methylation capture sequencing

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Study Overview The research aimed to uncover specific DNA methylation markers present in the blood …

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Dementia
Crossing the ‘Cookie Theft’ Corpus Chasm: Applying what BERT Learns from Outside Data to the ADReSS Challenge Dementia Detection Task

by myneuronews June 19, 2025

by myneuronews June 19, 2025

Study Overview The study investigates the intersection between artificial intelligence and dementia detection by utilizing …

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Dementia
Pharmacist-Driven Deprescribing to Reduce Anticholinergic Burden in Veterans With Dementia

by myneuronews June 18, 2025

by myneuronews June 18, 2025

Study Overview The investigation aimed to address the impact of pharmacist-led deprescribing initiatives in veterans …

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Impact of knowledge and attitude on inappropriate post-concussion behaviors in competitive cyclists
CONCLUSIONS: An association was found between concussion knowledge and return to competition without a period of rest post-injury, as well as between attitude toward concussion and return to competition with symptoms. Therefore, these findings can contribute to concussion education among cyclists.
Living in the Shadows: My Personal Perspective With Mental Health After a Concussion
CONCLUSION: This narrative highlights the anxiety and depressive symptoms experienced after concussion. By incorporating mental health nurses within concussion care, mental health issues can be addressed in a timely and approriate manner.
Knockout of indoleamine 2,3-dioxygenase 1 gene expression improves depressive and anxiety-like phenotypes in a murine model of mild traumatic brain injury
CONCLUSION: IDO deficiency prevented mTBI-induced anxiety- and depressive-like behaviors and altered neurotrophic factor levels regionally. These findings implicate IDO in post-mTBI behavioral and neurotrophic responses, warranting further study of kynurenine pathway metabolites and downstream signaling to clarify the mechanism underlying the role of IDO in mTBI outcomes.
Interpreting Change in Sport Concussion Assessment Tool-5th Edition (SCAT5) Scores in National Rugby League Women's Premiership Players
CONCLUSION: SCAT5 scores had low to moderate test-retest reliability across a one-year period. Reliable change scores for the SCAT5 were developed in this study for use with professional women rugby league players. When evaluating post-injury SCAT5 scores, it can be helpful to consider both what the score means compared to normative reference values and compared […]
An update on paediatric traumatic brain injury in the emergency department: a narrative review
Traumatic brain injury (TBI) affects an estimated 330,000 to 500,000 children annually in England and Wales and represents a significant burden on healthcare systems. Presentations range from mild to severe, and each case presents unique challenges to the Emergency Department (ED) clinicians. Most paediatric TBIs are mild, and several validated clinical decision rules (CDRs) such […]