Tag:

dementia

Stroke
Olfaction and Plasma Biomarkers of Alzheimer Disease and Neurodegeneration in the Atherosclerosis Risk in Communities Study

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Study Overview The research focused on the relationship between olfactory function and Alzheimer’s disease (AD), …

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Dementia
Olfaction and Plasma Biomarkers of Alzheimer Disease and Neurodegeneration in the Atherosclerosis Risk in Communities Study

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Link Between Olfaction and Neurodegeneration The sense of smell, or olfaction, has been increasingly recognized …

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Functional neurological disorders
Association of APOC1 with cortical atrophy during conversion to Alzheimer’s disease

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Association of Apolipoprotein C1 and Cognitive Decline The relationship between apolipoprotein C1 (APOC1) and cognitive …

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Dementia
Validating the Amyloid Cascade Through the Revised Criteria of Alzheimer’s Association Workgroup 2024 for Alzheimer Disease

by myneuronews May 13, 2025

by myneuronews May 13, 2025

Amyloid Cascade Hypothesis and Alzheimer Disease The Amyloid Cascade Hypothesis is a prominent concept in …

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Dementia
Intranasal Delivery of BACE1 siRNA and Berberine via Engineered Stem Cell Exosomes for the Treatment of Alzheimer’s Disease

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Treatment Strategy Overview In recent years, the exploration of innovative approaches to treat Alzheimer’s disease …

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Functional neurological disorders
Apolipoprotein E (APOE) and Alzheimer’s disease risk in a Ugandan population: A pilot case-control study

by myneuronews May 12, 2025

by myneuronews May 12, 2025

Apolipoprotein E Genotypes and Alzheimer’s Disease The study investigated the relationship between different genotypes of …

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Dementia
Unraveling sex differences in Alzheimer’s disease and related endophenotypes with brain proteomes

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Research Context The study of Alzheimer’s disease (AD) has gained considerable momentum as researchers explore …

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Movement Disorders
The prodromal individuals’ perspective on active recruitment for early detection of α-synucleinopathies

by myneuronews May 9, 2025

by myneuronews May 9, 2025

Perspective of Prodromal Individuals The perspective of individuals in the prodromal stage of α-synucleinopathies sheds …

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Dementia
Temporal transcriptomic changes in the THY-Tau22 mouse model of tauopathy display cell type- and sex-specific differences

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview The study investigates the temporal changes in gene expression occurring in the brains …

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Functional neurological disorders
GWAS by Subtraction to Disentangle RBD Genetic Background from α-Synucleinopathies

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Overview of RBD and α-Synucleinopathies As research into neurodegenerative disorders continues to evolve, it becomes …

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Impact of knowledge and attitude on inappropriate post-concussion behaviors in competitive cyclists
CONCLUSIONS: An association was found between concussion knowledge and return to competition without a period of rest post-injury, as well as between attitude toward concussion and return to competition with symptoms. Therefore, these findings can contribute to concussion education among cyclists.
Living in the Shadows: My Personal Perspective With Mental Health After a Concussion
CONCLUSION: This narrative highlights the anxiety and depressive symptoms experienced after concussion. By incorporating mental health nurses within concussion care, mental health issues can be addressed in a timely and approriate manner.
Knockout of indoleamine 2,3-dioxygenase 1 gene expression improves depressive and anxiety-like phenotypes in a murine model of mild traumatic brain injury
CONCLUSION: IDO deficiency prevented mTBI-induced anxiety- and depressive-like behaviors and altered neurotrophic factor levels regionally. These findings implicate IDO in post-mTBI behavioral and neurotrophic responses, warranting further study of kynurenine pathway metabolites and downstream signaling to clarify the mechanism underlying the role of IDO in mTBI outcomes.
Interpreting Change in Sport Concussion Assessment Tool-5th Edition (SCAT5) Scores in National Rugby League Women's Premiership Players
CONCLUSION: SCAT5 scores had low to moderate test-retest reliability across a one-year period. Reliable change scores for the SCAT5 were developed in this study for use with professional women rugby league players. When evaluating post-injury SCAT5 scores, it can be helpful to consider both what the score means compared to normative reference values and compared […]
An update on paediatric traumatic brain injury in the emergency department: a narrative review
Traumatic brain injury (TBI) affects an estimated 330,000 to 500,000 children annually in England and Wales and represents a significant burden on healthcare systems. Presentations range from mild to severe, and each case presents unique challenges to the Emergency Department (ED) clinicians. Most paediatric TBIs are mild, and several validated clinical decision rules (CDRs) such […]