Tag:

depression

Traumatic brain injury
Spautin-1 alleviates depression-like behaviors in mice after traumatic brain injury by inhibiting MMP3 expression in microglia in the Hippocampal CA1 region

by myneuronews September 12, 2025

by myneuronews September 12, 2025

Study Overview The research in question investigates the effects of Spautin-1, a compound known for …

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Traumatic brain injury
The prognostic value of a screening tool for psychological risk factors after mild traumatic brain injury: prospective studies in Canada and New Zealand

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Screening Tool Development The creation of a robust screening tool for identifying psychological risk factors …

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Traumatic brain injury
Concussive injuries induce neuronal stress-dependent tau mislocalization to dendritic spines with acrolein and functional network alteration in TBI-on-a-chip

by myneuronews September 11, 2025

by myneuronews September 11, 2025

Study Overview This research focuses on the cellular mechanisms involved in concussive injuries, specifically examining …

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Traumatic brain injury
Influences on the mental health and well-being of retired professional athletes from high contact team sports: a mixed methods systematic review

by myneuronews September 10, 2025

by myneuronews September 10, 2025

Study Overview This systematic review focuses on understanding the mental health and well-being of retired …

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Traumatic brain injury
Acute effects of sport-related concussion among adolescents with a self-reported history of treatment for anxiety or depression

by myneuronews September 9, 2025

by myneuronews September 9, 2025

Study Overview The investigation focuses on the immediate impacts of sport-related concussions in adolescents who …

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Traumatic brain injury
An Occurrence of Mass Psychogenic Illness: LeRoy, New York

by myneuronews September 8, 2025

by myneuronews September 8, 2025

Occurrence of Symptoms In late 2011, a series of unusual symptoms began to manifest among …

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Functional neurological disorders
An Occurrence of Mass Psychogenic Illness: LeRoy, New York

by myneuronews September 8, 2025

by myneuronews September 8, 2025

Mass Psychogenic Illness Overview Mass psychogenic illness, often referred to as mass hysteria, represents a …

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Functional neurological disorders
Mechanisms of motor dysfunction in functional neurological disorder: A narrative review

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Mechanisms of Motor Dysfunction Motor dysfunction in functional neurological disorder (FND) can be attributed to …

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Functional neurological disorders
Therapeutic education for patients with functional neurological disorders

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Therapeutic Approaches for FND Functional neurological disorders (FND) encompass a range of neurological symptoms that …

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Functional neurological disorders
Functional neurological disorders: history and current situation

by myneuronews September 6, 2025

by myneuronews September 6, 2025

Historical Perspective on FND Functional neurological disorders (FND) have a rich and complex history that …

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Macrophages and iNOS contribute to the effects of dural prolactin and repeated stress in mouse migraine models
Study Overview The investigation into the interplay between macrophages, inducible nitric oxide synthase (iNOS), and…
The biomarker and clinical changes across the Alzheimer’s continuum study (BCAS): rationale, design, and baseline characteristics of the first 1,013 participants
Study Overview The BCAS study focuses on understanding the progression of Alzheimer’s disease through a…
Women’s Issues and Female-specific Factors in Functional Neurological Disorder
Women’s Unique Experiences in FND Women facing Functional Neurological Disorder (FND) often encounter a unique…
Sex differences in the clinical characteristics of South African patients with functional seizures in a public and a private hospital
Sex Differences in Functional Seizures Research has increasingly highlighted the importance of sex differences in…
Developing Topics
Topic Identification In the early stages of research, selecting a compelling and relevant topic is…

Basic Science and Pathogenesis
CONCLUSION: These data identify sex differences in the extent of axonal pathologies in brain white matter acutely after TBI, which appears related to sex differences in axon diameter. Notably, these findings further shed light on insights that damaged and degenerating axons following TBI may provide a rich source of APP/Aβ as pathologic substrate contributing to […]
Basic Science and Pathogenesis
CONCLUSION: Young amateur contact sports players are at risk for structural and microstructural brain injuries, including enlarged ventricles, cavum septum pellucidum, microvascular injury, blood-brain barrier breach, interface astrocytosis, and glymphatic remodeling. Future studies are needed to clarify the association between these early structural injuries after RHI and risk for CTE.
The relationship between dispositional mindfulness and psychological, cognitive, and functional outcomes following mild traumatic brain injury
Background: Most individuals who sustain a mild uncomplicated Traumatic Brain Injury (mTBI) recover within 1-3 months. However, a significant proportion consistently report ongoing cognitive, psychological, and somatic sequelae, which can be functionally disabling and hinder active participation in society following injury. The present study examined dispositional mindfulness as a targetable protective factor as it pertains […]
Interaction of Obese Body Mass Index and Comorbidities on Inflammatory Profiles and Clinical Outcomes After Traumatic Brain Injury: A TRACK-TBI Study
CONCLUSIONS: Obesity and comorbidity profiles are associated with an inflammatory response with the potential to impact recovery; consideration of systemic health at the time of injury could improve recovery.
Multimodal Canonical Correlation Analysis with Joint Independent Component Analysis (mCCA+jICA) of IVIM and ASL MRI Reveals Perfusion and Diffusion Abnormalities in mTBI-A Pilot Study
Mild traumatic brain injury (mTBI) frequently causes subtle brain changes that are difficult to detect with conventional diagnostic approaches. In this exploratory pilot study, we combined tri-exponential intravoxel incoherent motion (IVIM) and pseudocontinuous arterial spin labeling (pCASL) MRI with Multimodal Canonical Correlation Analysis and joint independent component analysis (mCCA+jICA) to identify imaging signatures distinguishing mTBI […]