Tag:

diagnosis

Functional neurological disorders
Unveiling diverse clinical symptom patterns and neural activity profiles in major depressive disorder subtypes

by myneuronews May 16, 2025

by myneuronews May 16, 2025

Clinical Symptom Patterns in Major Depressive Disorder In the realm of mental health, Major Depressive …

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Movement Disorders
Associations Between Changes in Levels of Phosphorylated Tau and Severity of Cognitive Impairment in Early Alzheimer Disease

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Research Objectives The primary aim of this study is to explore the relationship between fluctuations …

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Headaches
Neurological complications of orthopoxvirus infections: neurotropism and neurovirulence

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Neurological Manifestations in Orthopoxvirus Infection Orthopoxvirus infections are associated with a variety of neurological manifestations …

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Stroke
Olfaction and Plasma Biomarkers of Alzheimer Disease and Neurodegeneration in the Atherosclerosis Risk in Communities Study

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Study Overview The research focused on the relationship between olfactory function and Alzheimer’s disease (AD), …

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Functional neurological disorders
Revealing heterogeneity in mild cognitive impairment based on individualized structural covariance network

by myneuronews May 15, 2025

by myneuronews May 15, 2025

Understanding Mild Cognitive Impairment Heterogeneity Mild cognitive impairment (MCI) is a clinical condition that marks …

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Functional neurological disorders
Fluid Biomarkers in Demyelinating Spectrum Disorders: Past, Present, and Prospects

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Fluid Biomarker Applications in Demyelinating Disorders Fluid biomarkers play a crucial role in the diagnosis …

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Traumatic brain injury
Characteristics of pediatric patients with sports-related concussions: A single site retrospective review

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Patient Demographics In the examination of pediatric patients with sports-related concussions, understanding the demographics of …

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Traumatic brain injury
Longitudinal assessment of post-concussion driving reaction time

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Background and Rationale Understanding the effects of concussive injuries on cognitive and motor skills is …

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Functional neurological disorders
Association of APOC1 with cortical atrophy during conversion to Alzheimer’s disease

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Association of Apoc1 with Alzheimer’s Disease Recent research has underscored the significance of the apolipoprotein …

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Functional neurological disorders
Progress in the Management of Mediastinal Ectopic Parathyroid Adenomas: The Role of Minimally Invasive Surgery

by myneuronews May 14, 2025

by myneuronews May 14, 2025

Advancements in Minimally Invasive Techniques In recent years, there has been an impressive evolution in …

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The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
Assessment of White Matter Changes Using Quantitative T1rho Mapping in an Open-Field Low-Intensity Blast Mouse Model of Mild Traumatic Brain Injury (mTBI)
Blast-induced mild traumatic brain injury (mTBI) occurs when shock waves travel through blood vessels and cerebrospinal fluid, leading to cerebral demyelination, which results in cognitive impairments and neuropsychiatric issues that impact quality of life. This study aims to evaluate myelin changes in white matter in mice with mTBI induced by an open-field low-intensity blast (LIB) […]