Tag:

diagnosis

Traumatic brain injury
Characterising Postural Orthostatic Tachycardia Syndrome (POTS) triggered by a viral illness compared to concussion or trauma

by myneuronews June 21, 2025

by myneuronews June 21, 2025

Understanding POTS and Its Triggers Postural Orthostatic Tachycardia Syndrome (POTS) is a form of dysautonomia …

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Functional neurological disorders
Dynamic electro-clinical features in Guanidinoacetate N-methyltransferase deficiency: A familial case series

by myneuronews June 21, 2025

by myneuronews June 21, 2025

Clinical Presentation and Symptoms Patients with Guanidinoacetate N-methyltransferase (GAMT) deficiency often exhibit a complex array …

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Dementia
Identification of diagnostic DNA methylation markers in the blood of Japanese Alzheimer’s disease patients using methylation capture sequencing

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Study Overview The research aimed to uncover specific DNA methylation markers present in the blood …

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Movement Disorders
Identifying kinematic biomarkers of the dystrophic phenotype in a zebrafish model of Duchenne muscular dystrophy

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Kinematic Biomarkers Identification Identifying kinematic biomarkers in the context of Duchenne muscular dystrophy (DMD) is …

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Headaches
Observational quality control study: insourcing multi-PCR-impact on the use of anti-infectives for patients with pleocytosis

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Study Overview The study investigates the effects of transitioning to an insourced multi-polymerase chain reaction …

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Traumatic brain injury
High-definition transcranial direct current stimulation improved dynamic postural control in patients with concussion: A randomised crossover trial

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Study Overview The investigation aimed to evaluate the impact of high-definition transcranial direct current stimulation …

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Traumatic brain injury
High-definition transcranial direct current stimulation improved dynamic postural control in patients with concussion: A randomised crossover trial

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Study Overview This research aimed to investigate the effects of high-definition transcranial direct current stimulation …

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Functional neurological disorders
Clinical progression and genetic pathways in body-first and brain-first Parkinson’s disease

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Clinical Features of Body-first and Brain-first Parkinson’s Disease Parkinson’s disease (PD) is a complex neurodegenerative …

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Functional neurological disorders
Investigating Resting-State Brain Activity in Adolescents with High-Functioning Autism Spectrum Disorder: Linking Fractional Amplitude of Low-Frequency Fluctuation to Clinical Symptoms

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Resting-State Brain Activity in Adolescents Resting-state brain activity in adolescents, particularly those diagnosed with high-functioning …

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Functional neurological disorders
Long-Term Survival in Brown-Vialetto-Van Laere Syndrome: A Case Report Highlighting Respiratory Care

by myneuronews June 20, 2025

by myneuronews June 20, 2025

Long-Term Outcomes in Brown-Vialetto-Van Laere Syndrome Brown-Vialetto-Van Laere Syndrome (BVVLS) is a rare neurological condition …

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The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
Assessment of White Matter Changes Using Quantitative T1rho Mapping in an Open-Field Low-Intensity Blast Mouse Model of Mild Traumatic Brain Injury (mTBI)
Blast-induced mild traumatic brain injury (mTBI) occurs when shock waves travel through blood vessels and cerebrospinal fluid, leading to cerebral demyelination, which results in cognitive impairments and neuropsychiatric issues that impact quality of life. This study aims to evaluate myelin changes in white matter in mice with mTBI induced by an open-field low-intensity blast (LIB) […]