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diagnosis

Functional neurological disorders
Genetic Sketch of Parkinson’s Disease in India

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Genetic Factors in Parkinson’s Disease Parkinson’s Disease (PD) is a multifactorial neurological disorder, with both …

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Functional neurological disorders
Improvement of functional paralysis following unexpected comatose states

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Overview of Functional Paralysis Functional paralysis, often categorized under Functional Neurological Disorder (FND), presents as …

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Functional neurological disorders
A functional seizure case in Wilson’s disease

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Case Presentation In this case, we assess a 30-year-old female who presented to the neurology …

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Functional neurological disorders
GWAS by Subtraction to Disentangle RBD Genetic Background from α-Synucleinopathies

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Background and Rationale The study of genetic factors influencing neurological conditions has gained momentum in …

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Functional neurological disorders
Choosing the right treatment for degenerative cervical myelopathy

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Understanding degenerative cervical myelopathy Degenerative cervical myelopathy (DCM) is a condition characterized by the gradual …

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Functional neurological disorders
A functional seizure case in Wilson’s disease

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Case Presentation This case involves a 25-year-old woman with a history of Wilson’s disease, a …

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Functional neurological disorders
Choosing the right treatment for degenerative cervical myelopathy

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Overview of Degenerative Cervical Myelopathy Degenerative cervical myelopathy (DCM) is a progressive condition characterized by …

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Dementia
Temporal transcriptomic changes in the THY-Tau22 mouse model of tauopathy display cell type- and sex-specific differences

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview The study investigates the temporal changes in gene expression occurring in the brains …

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Traumatic brain injury
Using baseline MRI radiomic features to predict the efficacy of repetitive transcranial magnetic stimulation in Alzheimer’s patients

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Study Overview This study investigates the potential of baseline MRI radiomic features to forecast the …

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Traumatic brain injury
Moving Sounds Increase Postural Visual Dependence in Adults With Chronic Traumatic Brain Injury

by myneuronews May 7, 2025

by myneuronews May 7, 2025

Impact of Moving Sounds on Postural Control In recent studies, the relationship between auditory stimuli …

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Exo70 Protects Against Memory and Synaptic Impairments Following Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI), a leading cause of disability in young adults, often results from external forces that damage the brain. Cellularly, mTBI induces oxidative stress, characterized by excessive reactive oxygen species (ROS) and diminished antioxidant capacity. This redox imbalance disrupts hippocampal glutamatergic transmission and synaptic plasticity, where NMDA receptors (NMDARs) are crucial. The […]
Neurocognitive Outcomes After Extracranial Surgery and General Anesthesia in Patients with a History of Mild-to-Moderate Traumatic Brain Injury: Systemic Review and Meta-Analysis
Accelerated neurocognitive decline associated with surgeries under general anesthesia (GA), a phenomenon referred to as postoperative neurocognitive disorder (PND), is a significant public health concern. It not only poses inherent risks but may also contribute to the development of other neurodegenerative disorders. We systematically searched five databases for studies examining cognitive function in patients with […]
The Diagnostic and Prognostic Role of Biomarkers in Mild Traumatic Brain Injury: An Umbrella Meta-Analysis
CONCLUSIONS: The findings underscore the clinical promise of fluid biomarkers in the management of mTBI. S100B and GFAP are particularly valuable as screening and confirmatory markers, respectively. Nonetheless, further standardization of biomarker thresholds and additional longitudinal studies are necessary to validate the roles of UCH-L1, NfL, and Tau protein. The integration of these biomarkers into […]
Mechanisms Underlying Hyperexcitability: Combining Mossy Fiber Sprouting and Mossy Cell Loss in Neural Network Model of the Dentate Gyrus
Background/Objectives: A concussive head injury increases the likelihood of temporal lobe epilepsy through mechanisms that are not entirely understood. This study aimed to investigate how two key histopathological features shared by both TLE (temporal lobe epilepsy) and head injury-mossy fiber sprouting and hilar excitatory cell loss-contribute to the modulation of dentate gyrus excitability. Methods: A […]
Neurobiology of Chronic Pain, Posttraumatic Stress Disorder, and Mild Traumatic Brain Injury
CONCLUSIONS: Common therapeutic processes, such as focusing on sensitization, might be helpful for these conditions. As for causal mechanisms related to sensitization in the causality of psychological injuries, the major ones hypothesized relate to the biopsychosocial model, psychological control, and activation-inhibition coordination.