Tag:

diagnosis

Headaches
Diagnostic Yield of CT Myelography for the Identification of CSF Leaks in Patients with Post Dural Puncture Headache

by myneuronews November 24, 2025

by myneuronews November 24, 2025

Study Overview This research focuses on assessing the diagnostic efficacy of CT myelography in identifying …

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Traumatic brain injury
A Clinical Practice Guideline for Adults With Concussion/Mild TBI: We Can’t Wait Until 2042

by myneuronews November 24, 2025

by myneuronews November 24, 2025

Background and Rationale To understand the importance of addressing concussion and mild traumatic brain injury …

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Traumatic brain injury
Interpreting Scores from Adolescents with Attention-Deficit/Hyperactivity Disorder on Sway Medical System Balance and Cognitive Modules

by myneuronews November 24, 2025

by myneuronews November 24, 2025

Background and Rationale The increasing prevalence of Attention-Deficit/Hyperactivity Disorder (ADHD) among adolescents has led to …

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Traumatic brain injury
Comment on Mavroudis et al. Post-Traumatic Epilepsy After Mild and Moderate Traumatic Brain Injury: A Narrative Review and Development of a Clinical Decision Tool. Reports 2025, 8, 193

by myneuronews November 24, 2025

by myneuronews November 24, 2025

Study Overview The article by Mavroudis et al. presents a comprehensive evaluation of post-traumatic epilepsy …

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Dementia
Single-nucleus and spatial transcriptomic profiling of human temporal cortex and white matter reveals key associations with AD pathology

by myneuronews November 24, 2025

by myneuronews November 24, 2025

Study Overview This study centers on the intricate relationships between cellular profiles in the human …

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Functional neurological disorders
Chronic pain in Functional Neurological Disorders: clinical outcomes from an inpatient rehabilitation program

by myneuronews November 22, 2025

by myneuronews November 22, 2025

Clinical Outcomes of Rehabilitation Recent studies have highlighted the significant impact that rehabilitation programs have …

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Functional neurological disorders
Chronic pain in Functional Neurological Disorders: clinical outcomes from an inpatient rehabilitation program

by myneuronews November 22, 2025

by myneuronews November 22, 2025

Clinical Characteristics of Chronic Pain Chronic pain is a prevalent issue among individuals with Functional …

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Functional neurological disorders
Chronic pain in Functional Neurological Disorders: clinical outcomes from an inpatient rehabilitation program

by myneuronews November 22, 2025

by myneuronews November 22, 2025

Chronic Pain Assessment in FND Chronic pain is a significant issue for many individuals with …

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Functional neurological disorders
Prepulse inhibition of the blink reflex in functional neurological disorder and fibromyalgia

by myneuronews November 21, 2025

by myneuronews November 21, 2025

Prepulse Inhibition Mechanisms Prepulse inhibition (PPI) is a neurological phenomenon whereby a weak stimulus (the …

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Functional neurological disorders
Prepulse inhibition of the blink reflex in functional neurological disorder and fibromyalgia

by myneuronews November 21, 2025

by myneuronews November 21, 2025

Clinical Significance of PPI in FND and Fibromyalgia The study of prepulse inhibition (PPI) provides …

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Incretin Mimetics as Potential Therapeutics for Concussion and Traumatic Brain Injury: A Narrative Review
Traumatic brain injury (TBI) represents a significant health concern, with an estimated 70 million annual cases worldwide. Mild brain trauma (concussions) is the most common TBI (81%), followed by moderate (11%) and severe (8%). Cytokine release and neuroinflammation after TBI may cause blood-brain barrier and tissue damage, triggering unfavorable outcomes, including disabilities and mortality. Current […]
N-Stearidonoylethanolamine Restores CA1 Synaptic Integrity and Reduces Astrocytic Reactivity After Mild Traumatic Brain Injury
Mild traumatic brain injury (mTBI) disrupts hippocampal network function through coordinated alterations in glial reactivity, synaptic integrity, and adult neurogenesis. Effective therapeutic approaches targeting these interconnected processes remain limited. Lipid-derived molecules capable of modulating these mTBI-induced disturbances are emerging as promising neuroprotective candidates. Here, we investigated the effects of N-stearidonylethanolamine (SDEA), an ω-3 ethanolamide, in […]
Effects of persistent post-concussion symptoms on neurocognitive, motor, and neurophysiological outcomes
CONCLUSION: The PPCS group demonstrated greater symptom reporting and severity, worse neurocognitive performance, worse balance and gait performance, and altered neurophysiology. Further, females with PPCS demonstrated worse balance and gait performance compared to all other groups.
Injury-environment interaction: microglial priming by mTBI creates vulnerability to subsequent stress via the HMGB1-RAGE axis
CONCLUSION: Our study untangles a "priming-triggering" mechanism of injury-environment interaction, identifying the HMGB1-RAGE axis as its key molecular mediator. This finding not only enhances our understanding of how latent vulnerability transitions into overt neuropsychiatric disease, but also provides a promising target for preventive intervention.
Relationship between illness perceptions, coping style and post-concussion symptoms after systemic traumatic injury: A comparison of those with and without mild traumatic brain injury
Research has reported variable findings when investigating the relationship between outcome and coping style and illness perceptions after mild traumatic brain injury (mTBI). The present study investigated 138 individuals who had been admitted to hospital after suffering a traumatic systemic injury, with 91 of these individuals also fulfilling criteria for mTBI and 47 comprising a […]